1,265 research outputs found

    An examination of the verbal behaviour of intergroup discrimination

    Get PDF
    This thesis examined relationships between psychological flexibility, psychological inflexibility, prejudicial attitudes, and dehumanization across three cross-sectional studies with an additional proposed experimental study. Psychological flexibility refers to mindful attention to the present moment, willing acceptance of private experiences, and engaging in behaviours congruent with one’s freely chosen values. Inflexibility, on the other hand, indicates a tendency to suppress unwanted thoughts and emotions, entanglement with one’s thoughts, and rigid behavioural patterns. Study 1 found limited correlations between inflexibility and sexism, racism, homonegativity, and dehumanization. Study 2 demonstrated more consistent positive associations between inflexibility and prejudice. And Study 3 controlled for right-wing authoritarianism and social dominance orientation, finding inflexibility predicted hostile sexism and racism beyond these factors. While showing some relationships, particularly with sexism and racism, psychological inflexibility did not consistently correlate with varied prejudices across studies. The proposed randomized controlled trial aims to evaluate an Acceptance and Commitment Therapy intervention to reduce sexism through enhanced psychological flexibility. Overall, findings provide mixed support for the utility of flexibility-based skills in addressing complex societal prejudices. Research should continue examining flexibility integrated with socio-cultural approaches to promote equity

    LIPIcs, Volume 251, ITCS 2023, Complete Volume

    Get PDF
    LIPIcs, Volume 251, ITCS 2023, Complete Volum

    The Individual And Their World

    Get PDF

    Using machine learning to predict pathogenicity of genomic variants throughout the human genome

    Get PDF
    Geschätzt mehr als 6.000 Erkrankungen werden durch Veränderungen im Genom verursacht. Ursachen gibt es viele: Eine genomische Variante kann die Translation eines Proteins stoppen, die Genregulation stören oder das Spleißen der mRNA in eine andere Isoform begünstigen. All diese Prozesse müssen überprüft werden, um die zum beschriebenen Phänotyp passende Variante zu ermitteln. Eine Automatisierung dieses Prozesses sind Varianteneffektmodelle. Mittels maschinellem Lernen und Annotationen aus verschiedenen Quellen bewerten diese Modelle genomische Varianten hinsichtlich ihrer Pathogenität. Die Entwicklung eines Varianteneffektmodells erfordert eine Reihe von Schritten: Annotation der Trainingsdaten, Auswahl von Features, Training verschiedener Modelle und Selektion eines Modells. Hier präsentiere ich ein allgemeines Workflow dieses Prozesses. Dieses ermöglicht es den Prozess zu konfigurieren, Modellmerkmale zu bearbeiten, und verschiedene Annotationen zu testen. Der Workflow umfasst außerdem die Optimierung von Hyperparametern, Validierung und letztlich die Anwendung des Modells durch genomweites Berechnen von Varianten-Scores. Der Workflow wird in der Entwicklung von Combined Annotation Dependent Depletion (CADD), einem Varianteneffektmodell zur genomweiten Bewertung von SNVs und InDels, verwendet. Durch Etablierung des ersten Varianteneffektmodells für das humane Referenzgenome GRCh38 demonstriere ich die gewonnenen Möglichkeiten Annotationen aufzugreifen und neue Modelle zu trainieren. Außerdem zeige ich, wie Deep-Learning-Scores als Feature in einem CADD-Modell die Vorhersage von RNA-Spleißing verbessern. Außerdem werden Varianteneffektmodelle aufgrund eines neuen, auf Allelhäufigkeit basierten, Trainingsdatensatz entwickelt. Diese Ergebnisse zeigen, dass der entwickelte Workflow eine skalierbare und flexible Möglichkeit ist, um Varianteneffektmodelle zu entwickeln. Alle entstandenen Scores sind unter cadd.gs.washington.edu und cadd.bihealth.org frei verfügbar.More than 6,000 diseases are estimated to be caused by genomic variants. This can happen in many possible ways: a variant may stop the translation of a protein, interfere with gene regulation, or alter splicing of the transcribed mRNA into an unwanted isoform. It is necessary to investigate all of these processes in order to evaluate which variant may be causal for the deleterious phenotype. A great help in this regard are variant effect scores. Implemented as machine learning classifiers, they integrate annotations from different resources to rank genomic variants in terms of pathogenicity. Developing a variant effect score requires multiple steps: annotation of the training data, feature selection, model training, benchmarking, and finally deployment for the model's application. Here, I present a generalized workflow of this process. It makes it simple to configure how information is converted into model features, enabling the rapid exploration of different annotations. The workflow further implements hyperparameter optimization, model validation and ultimately deployment of a selected model via genome-wide scoring of genomic variants. The workflow is applied to train Combined Annotation Dependent Depletion (CADD), a variant effect model that is scoring SNVs and InDels genome-wide. I show that the workflow can be quickly adapted to novel annotations by porting CADD to the genome reference GRCh38. Further, I demonstrate the integration of deep-neural network scores as features into a new CADD model, improving the annotation of RNA splicing events. Finally, I apply the workflow to train multiple variant effect models from training data that is based on variants selected by allele frequency. In conclusion, the developed workflow presents a flexible and scalable method to train variant effect scores. All software and developed scores are freely available from cadd.gs.washington.edu and cadd.bihealth.org

    A robotic platform for precision agriculture and applications

    Get PDF
    Agricultural techniques have been improved over the centuries to match with the growing demand of an increase in global population. Farming applications are facing new challenges to satisfy global needs and the recent technology advancements in terms of robotic platforms can be exploited. As the orchard management is one of the most challenging applications because of its tree structure and the required interaction with the environment, it was targeted also by the University of Bologna research group to provide a customized solution addressing new concept for agricultural vehicles. The result of this research has blossomed into a new lightweight tracked vehicle capable of performing autonomous navigation both in the open-filed scenario and while travelling inside orchards for what has been called in-row navigation. The mechanical design concept, together with customized software implementation has been detailed to highlight the strengths of the platform and some further improvements envisioned to improve the overall performances. Static stability testing has proved that the vehicle can withstand steep slopes scenarios. Some improvements have also been investigated to refine the estimation of the slippage that occurs during turning maneuvers and that is typical of skid-steering tracked vehicles. The software architecture has been implemented using the Robot Operating System (ROS) framework, so to exploit community available packages related to common and basic functions, such as sensor interfaces, while allowing dedicated custom implementation of the navigation algorithm developed. Real-world testing inside the university’s experimental orchards have proven the robustness and stability of the solution with more than 800 hours of fieldwork. The vehicle has also enabled a wide range of autonomous tasks such as spraying, mowing, and on-the-field data collection capabilities. The latter can be exploited to automatically estimate relevant orchard properties such as fruit counting and sizing, canopy properties estimation, and autonomous fruit harvesting with post-harvesting estimations.Le tecniche agricole sono state migliorate nel corso dei secoli per soddisfare la crescente domanda di aumento della popolazione mondiale. I recenti progressi tecnologici in termini di piattaforme robotiche possono essere sfruttati in questo contesto. Poiché la gestione del frutteto è una delle applicazioni più impegnative, a causa della sua struttura arborea e della necessaria interazione con l'ambiente, è stata oggetto di ricerca per fornire una soluzione personalizzata che sviluppi un nuovo concetto di veicolo agricolo. Il risultato si è concretizzato in un veicolo cingolato leggero, capace di effettuare una navigazione autonoma sia nello scenario di pieno campo che all'interno dei frutteti (navigazione interfilare). La progettazione meccanica, insieme all'implementazione del software, sono stati dettagliati per evidenziarne i punti di forza, accanto ad alcuni ulteriori miglioramenti previsti per incrementarne le prestazioni complessive. I test di stabilità statica hanno dimostrato che il veicolo può resistere a ripidi pendii. Sono stati inoltre studiati miglioramenti per affinare la stima dello slittamento che si verifica durante le manovre di svolta, tipico dei veicoli cingolati. L'architettura software è stata implementata utilizzando il framework Robot Operating System (ROS), in modo da sfruttare i pacchetti disponibili relativi a componenti base, come le interfacce dei sensori, e consentendo al contempo un'implementazione personalizzata degli algoritmi di navigazione sviluppati. I test in condizioni reali all'interno dei frutteti sperimentali dell'università hanno dimostrato la robustezza e la stabilità della soluzione con oltre 800 ore di lavoro sul campo. Il veicolo ha permesso di attivare e svolgere un'ampia gamma di attività agricole in maniera autonoma, come l'irrorazione, la falciatura e la raccolta di dati sul campo. Questi ultimi possono essere sfruttati per stimare automaticamente le proprietà più rilevanti del frutteto, come il conteggio e la calibratura dei frutti, la stima delle proprietà della chioma e la raccolta autonoma dei frutti con stime post-raccolta

    Security and Privacy for Modern Wireless Communication Systems

    Get PDF
    The aim of this reprint focuses on the latest protocol research, software/hardware development and implementation, and system architecture design in addressing emerging security and privacy issues for modern wireless communication networks. Relevant topics include, but are not limited to, the following: deep-learning-based security and privacy design; covert communications; information-theoretical foundations for advanced security and privacy techniques; lightweight cryptography for power constrained networks; physical layer key generation; prototypes and testbeds for security and privacy solutions; encryption and decryption algorithm for low-latency constrained networks; security protocols for modern wireless communication networks; network intrusion detection; physical layer design with security consideration; anonymity in data transmission; vulnerabilities in security and privacy in modern wireless communication networks; challenges of security and privacy in node–edge–cloud computation; security and privacy design for low-power wide-area IoT networks; security and privacy design for vehicle networks; security and privacy design for underwater communications networks

    Metaverse. Old urban issues in new virtual cities

    Get PDF
    Recent years have seen the arise of some early attempts to build virtual cities, utopias or affective dystopias in an embodied Internet, which in some respects appear to be the ultimate expression of the neoliberal city paradigma (even if virtual). Although there is an extensive disciplinary literature on the relationship between planning and virtual or augmented reality linked mainly to the gaming industry, this often avoids design and value issues. The observation of some of these early experiences - Decentraland, Minecraft, Liberland Metaverse, to name a few - poses important questions and problems that are gradually becoming inescapable for designers and urban planners, and allows us to make some partial considerations on the risks and potentialities of these early virtual cities

    On hierarchical clustering-based approach for RDDBS design

    Get PDF
    Distributed database system (DDBS) design is still an open challenge even after decades of research, especially in a dynamic network setting. Hence, to meet the demands of high-speed data gathering and for the management and preservation of huge systems, it is important to construct a distributed database for real-time data storage. Incidentally, some fragmentation schemes, such as horizontal, vertical, and hybrid, are widely used for DDBS design. At the same time, data allocation could not be done without first physically fragmenting the data because the fragmentation process is the foundation of the DDBS design. Extensive research have been conducted to develop effective solutions for DDBS design problems. But the great majority of them barely consider the RDDBS\u27s initial design. Therefore, this work aims at proposing a clustering-based horizontal fragmentation and allocation technique to handle both the early and late stages of the DDBS design. To ensure that each operation flows into the next without any increase in complexity, fragmentation and allocation are done simultaneously. With this approach, the main goals are to minimize communication expenses, response time, and irrelevant data access. Most importantly, it has been observed that the proposed approach may effectively expand RDDBS performance by simultaneously fragmenting and assigning various relations. Through simulations and experiments on synthetic and real databases, we demonstrate the viability of our strategy and how it considerably lowers communication costs for typical access patterns at both the early and late stages of design
    • …
    corecore