6,580 research outputs found
Batch and median neural gas
Neural Gas (NG) constitutes a very robust clustering algorithm given
euclidian data which does not suffer from the problem of local minima like
simple vector quantization, or topological restrictions like the
self-organizing map. Based on the cost function of NG, we introduce a batch
variant of NG which shows much faster convergence and which can be interpreted
as an optimization of the cost function by the Newton method. This formulation
has the additional benefit that, based on the notion of the generalized median
in analogy to Median SOM, a variant for non-vectorial proximity data can be
introduced. We prove convergence of batch and median versions of NG, SOM, and
k-means in a unified formulation, and we investigate the behavior of the
algorithms in several experiments.Comment: In Special Issue after WSOM 05 Conference, 5-8 september, 2005, Pari
Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates
The study of cerebral anatomy in developing neonates is of great importance for
the understanding of brain development during the early period of life. This
dissertation therefore focuses on three challenges in the modelling of cerebral
anatomy in neonates during brain development. The methods that have been
developed all use Magnetic Resonance Images (MRI) as source data.
To facilitate study of vascular development in the neonatal period, a set of image
analysis algorithms are developed to automatically extract and model cerebral
vessel trees. The whole process consists of cerebral vessel tracking from
automatically placed seed points, vessel tree generation, and vasculature
registration and matching. These algorithms have been tested on clinical Time-of-
Flight (TOF) MR angiographic datasets.
To facilitate study of the neonatal cortex a complete cerebral cortex segmentation
and reconstruction pipeline has been developed. Segmentation of the neonatal
cortex is not effectively done by existing algorithms designed for the adult brain
because the contrast between grey and white matter is reversed. This causes pixels
containing tissue mixtures to be incorrectly labelled by conventional methods. The
neonatal cortical segmentation method that has been developed is based on a novel
expectation-maximization (EM) method with explicit correction for mislabelled
partial volume voxels. Based on the resulting cortical segmentation, an implicit
surface evolution technique is adopted for the reconstruction of the cortex in
neonates. The performance of the method is investigated by performing a detailed
landmark study.
To facilitate study of cortical development, a cortical surface registration algorithm
for aligning the cortical surface is developed. The method first inflates extracted
cortical surfaces and then performs a non-rigid surface registration using free-form
deformations (FFDs) to remove residual alignment. Validation experiments using
data labelled by an expert observer demonstrate that the method can capture local
changes and follow the growth of specific sulcus
Segmentation of ultrasound images of thyroid nodule for assisting fine needle aspiration cytology
The incidence of thyroid nodule is very high and generally increases with the
age. Thyroid nodule may presage the emergence of thyroid cancer. The thyroid
nodule can be completely cured if detected early. Fine needle aspiration
cytology is a recognized early diagnosis method of thyroid nodule. There are
still some limitations in the fine needle aspiration cytology, and the
ultrasound diagnosis of thyroid nodule has become the first choice for
auxiliary examination of thyroid nodular disease. If we could combine medical
imaging technology and fine needle aspiration cytology, the diagnostic rate of
thyroid nodule would be improved significantly. The properties of ultrasound
will degrade the image quality, which makes it difficult to recognize the edges
for physicians. Image segmentation technique based on graph theory has become a
research hotspot at present. Normalized cut (Ncut) is a representative one,
which is suitable for segmentation of feature parts of medical image. However,
how to solve the normalized cut has become a problem, which needs large memory
capacity and heavy calculation of weight matrix. It always generates over
segmentation or less segmentation which leads to inaccurate in the
segmentation. The speckle noise in B ultrasound image of thyroid tumor makes
the quality of the image deteriorate. In the light of this characteristic, we
combine the anisotropic diffusion model with the normalized cut in this paper.
After the enhancement of anisotropic diffusion model, it removes the noise in
the B ultrasound image while preserves the important edges and local details.
This reduces the amount of computation in constructing the weight matrix of the
improved normalized cut and improves the accuracy of the final segmentation
results. The feasibility of the method is proved by the experimental results.Comment: 15pages,13figure
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