LSU Research Fall 2012

LSU Research is published annually by the Office of Research & Economic Development, Louisiana State University.https://digitalcommons.lsu.edu/research-magazine/1003/thumbnail.jp

Decoupling User Interface Design Using Libraries of Reusable Components

The integration of electronic and mechanical hardware, software and interaction design presents a challenging design space for researchers developing physical user interfaces and interactive artifacts. Currently in the academic research community, physical user interfaces and interactive artifacts are predominantly designed and prototyped either as one-off instances from the ground up, or using functionally rich hardware toolkits and prototyping systems. During this prototyping phase, undertaking an integral design of the interface or interactive artifact’s electronic hardware is frequently constraining due to the tight couplings between the different design realms and the typical need for iterations as the design matures. Several current toolkit designs have consequently embraced component-sharing and component-swapping modular designs with a view to extending flexibility and improving researcher freedom by disentangling and softening the cause-effect couplings. Encouraged by early successes of these toolkits, this research work strives to further enhance these freedoms by pursuing an alternative style and dimension of hardware modularity. Another motivation is our goal to facilitate the design and development of certain classes of interfaces and interactive artifacts for which current electronic design approaches are argued to be restrictively constraining (e.g., relating to scale and complexity). Unfortunately, this goal of a new platform architecture is met with conceptual and technical challenges on the embedded system networking front. In response, this research investigates and extends a growing field of multi-module distributed embedded systems. We identify and characterize a sub-class of these systems, calling them embedded aggregates. We then outline and develop a framework for realizing the embedded aggregate class of systems. Toward this end, this thesis examines several architectures, topologies and communication protocols, making the case for and substantial steps toward the development of a suite of networking protocols and control algorithms to support embedded aggregates. We define a set of protocols, mechanisms and communication packets that collectively form the underlying framework for the aggregates. Following the aggregates design, we develop blades and tiles to support user interface researchers

The common marmoset genome provides insight into primate biology and evolution

We report the whole-genome sequence of the common marmoset (Callithrix jacchus). The 2.26-Gb genome of a female marmoset was assembled using Sanger read data (6×) and a whole-genome shotgun strategy. A first analysis has permitted comparison with the genomes of apes and Old World monkeys and the identification of specific features that might contribute to the unique biology of this diminutive primate, including genetic changes that may influence body size, frequent twinning and chimerism. We observed positive selection in growth hormone/insulin-like growth factor genes (growth pathways), respiratory complex I genes (metabolic pathways), and genes encoding immunobiological factors and proteases (reproductive and immunity pathways). In addition, both protein-coding and microRNA genes related to reproduction exhibited evidence of rapid sequence evolution. This genome sequence for a New World monkey enables increased power for comparative analyses among available primate genomes and facilitates biomedical research application. © 2014 Nature America, Inc