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A Framework for Directional and Higher-Order Reconstruction in Photoacoustic Tomography
Photoacoustic tomography is a hybrid imaging technique that combines high
optical tissue contrast with high ultrasound resolution. Direct reconstruction
methods such as filtered backprojection, time reversal and least squares suffer
from curved line artefacts and blurring, especially in case of limited angles
or strong noise. In recent years, there has been great interest in regularised
iterative methods. These methods employ prior knowledge on the image to provide
higher quality reconstructions. However, easy comparisons between regularisers
and their properties are limited, since many tomography implementations heavily
rely on the specific regulariser chosen. To overcome this bottleneck, we
present a modular reconstruction framework for photoacoustic tomography. It
enables easy comparisons between regularisers with different properties, e.g.
nonlinear, higher-order or directional. We solve the underlying minimisation
problem with an efficient first-order primal-dual algorithm. Convergence rates
are optimised by choosing an operator dependent preconditioning strategy. Our
reconstruction methods are tested on challenging 2D synthetic and experimental
data sets. They outperform direct reconstruction approaches for strong noise
levels and limited angle measurements, offering immediate benefits in terms of
acquisition time and quality. This work provides a basic platform for the
investigation of future advanced regularisation methods in photoacoustic
tomography.Comment: submitted to "Physics in Medicine and Biology". Changes from v1 to
v2: regularisation with directional wavelet has been added; new experimental
tests have been include
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