Automatic Classification of Human Epithelial Type 2 Cell Indirect Immunofluorescence Images using Cell Pyramid Matching

This paper describes a novel system for automatic classification of images obtained from Anti-Nuclear Antibody (ANA) pathology tests on Human Epithelial type 2 (HEp-2) cells using the Indirect Immunofluorescence (IIF) protocol. The IIF protocol on HEp-2 cells has been the hallmark method to identify the presence of ANAs, due to its high sensitivity and the large range of antigens that can be detected. However, it suffers from numerous shortcomings, such as being subjective as well as time and labour intensive. Computer Aided Diagnostic (CAD) systems have been developed to address these problems, which automatically classify a HEp-2 cell image into one of its known patterns (eg. speckled, homogeneous). Most of the existing CAD systems use handpicked features to represent a HEp-2 cell image, which may only work in limited scenarios. We propose a novel automatic cell image classification method termed Cell Pyramid Matching (CPM), which is comprised of regional histograms of visual words coupled with the Multiple Kernel Learning framework. We present a study of several variations of generating histograms and show the efficacy of the system on two publicly available datasets: the ICPR HEp-2 cell classification contest dataset and the SNPHEp-2 dataset.Comment: arXiv admin note: substantial text overlap with arXiv:1304.126

AXES at TRECVID 2012: KIS, INS, and MED

The AXES project participated in the interactive instance search task (INS), the known-item search task (KIS), and the multimedia event detection task (MED) for TRECVid 2012. As in our TRECVid 2011 system, we used nearly identical search systems and user interfaces for both INS and KIS. Our interactive INS and KIS systems focused this year on using classifiers trained at query time with positive examples collected from external search engines. Participants in our KIS experiments were media professionals from the BBC; our INS experiments were carried out by students and researchers at Dublin City University. We performed comparatively well in both experiments. Our best KIS run found 13 of the 25 topics, and our best INS runs outperformed all other submitted runs in terms of P@100. For MED, the system presented was based on a minimal number of low-level descriptors, which we chose to be as large as computationally feasible. These descriptors are aggregated to produce high-dimensional video-level signatures, which are used to train a set of linear classifiers. Our MED system achieved the second-best score of all submitted runs in the main track, and best score in the ad-hoc track, suggesting that a simple system based on state-of-the-art low-level descriptors can give relatively high performance. This paper describes in detail our KIS, INS, and MED systems and the results and findings of our experiments