Pinning down loosened prostheses : imaging and planning of percutaneous hip refixation

This thesis examines how computer software can be used to analyse medical images of an aseptically loosening hip prosthesis, and subsequently to plan and guide a minimally invasive cement injection procedure to stabilize the prosthesis. We addressed the detection and measurement of periprosthetic bone lesions from CT image volumes. Post-operative CTs of patients treated at our institution were analysed. We developed tissue classification algorithms that automatically label periprosthetic bone, cement and fibrous interface tissue. An existing particle-based multi-material meshing algorithm was adapted for improved Finite Element model creation. We then presented HipRFX, a proof-of-concept software tool for planning and guidance during percutaneous cement refixation procedures.Advanced School for Computing and Imaging (ASCI), Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO), Stichting Anna Fonds, Technologiestichting STWUBL - phd migration 201