Integration of Biological Sources: Exploring the Case of Protein Homology

Data integration is a key issue in the domain of bioin- formatics, which deals with huge amounts of heteroge- neous biological data that grows and changes rapidly. This paper serves as an introduction in the field of bioinformatics and the biological concepts it deals with, and an exploration of the integration problems a bioinformatics scientist faces. We examine ProGMap, an integrated protein homology system used by bioin- formatics scientists at Wageningen University, and several use cases related to protein homology. A key issue we identify is the huge manual effort required to unify source databases into a single resource. Un- certain databases are able to contain several possi- ble worlds, and it has been proposed that they can be used to significantly reduce initial integration efforts. We propose several directions for future work where uncertain databases can be applied to bioinformatics, with the goal of furthering the cause of bioinformatics integration

BIM semantic-enrichment for built heritage representation

In the built heritage context, BIM has shown difficulties in representing and managing the large and complex knowledge related to non-geometrical aspects of the heritage. Within this scope, this paper focuses on a domain-specific semantic-enrichment of BIM methodology, aimed at fulfilling semantic representation requirements of built heritage through Semantic Web technologies. To develop this semantic-enriched BIM approach, this research relies on the integration of a BIM environment with a knowledge base created through information ontologies. The result is knowledge base system - and a prototypal platform - that enhances semantic representation capabilities of BIM application to architectural heritage processes. It solves the issue of knowledge formalization in cultural heritage informative models, favouring a deeper comprehension and interpretation of all the building aspects. Its open structure allows future research to customize, scale and adapt the knowledge base different typologies of artefacts and heritage activities

A framework for utility data integration in the UK

In this paper we investigate various factors which prevent utility knowledge from being fully exploited and suggest that integration techniques can be applied to improve the quality of utility records. The paper suggests a framework which supports knowledge and data integration. The framework supports utility integration at two levels: the schema and data level. Schema level integration ensures that a single, integrated geospatial data set is available for utility enquiries. Data level integration improves utility data quality by reducing inconsistency, duplication and conflicts. Moreover, the framework is designed to preserve autonomy and distribution of utility data. The ultimate aim of the research is to produce an integrated representation of underground utility infrastructure in order to gain more accurate knowledge of the buried services. It is hoped that this approach will enable us to understand various problems associated with utility data, and to suggest some potential techniques for resolving them

1st INCF Workshop on Sustainability of Neuroscience Databases

The goal of the workshop was to discuss issues related to the sustainability of neuroscience databases, identify problems and propose solutions, and formulate recommendations to the INCF. The report summarizes the discussions of invited participants from the neuroinformatics community as well as from other disciplines where sustainability issues have already been approached. The recommendations for the INCF involve rating, ranking, and supporting database sustainability

A semantic web approach for built heritage representation

In a built heritage process, meant as a structured system of activities aimed at the investigation, preservation, and management of architectural heritage, any task accomplished by the several actors involved in it is deeply influenced by the way the knowledge is represented and shared. In the current heritage practice, knowledge representation and management have shown several limitations due to the difficulty of dealing with large amount of extremely heterogeneous data. On this basis, this research aims at extending semantic web approaches and technologies to architectural heritage knowledge management in order to provide an integrated and multidisciplinary representation of the artifact and of the knowledge necessary to support any decision or any intervention and management activity. To this purpose, an ontology-based system, representing the knowledge related to the artifact and its contexts, has been developed through the formalization of domain-specific entities and relationships between them