3 research outputs found
Der Lehrstuhl Datenbank- und Informationssysteme der Universität Rostock
Im Jahr 2014 feierte der Lehrstuhl Datenbank- und Informationssysteme (LS DBIS) an der Universität Rostock sein zwanzigjähriges Bestehen. Zur Jubiläumsveranstaltung mit ehemaligen und aktuellen Studenten, Mitarbeitern, Kollegen und Kooperationspartnern wurde diverses Material aus 20 Jahren aufbereitet. In diesem Beitrag soll daraus ein Rückblick auf 20 Jahre Forschung und Lehre im Bereich Datenbank- und Informationssysteme sowie ein Ein- und Ausblick auf aktuelle Forschungsarbeiten gegeben werden
An experimental study and evaluation of a new architecture for clinical decision support - integrating the openEHR specifications for the Electronic Health Record with Bayesian Networks
Healthcare informatics still lacks wide-scale adoption of intelligent decision
support methods, despite continuous increases in computing power and
methodological advances in scalable computation and machine learning, over
recent decades. The potential has long been recognised, as evidenced in the
literature of the domain, which is extensively reviewed.
The thesis identifies and explores key barriers to adoption of clinical decision
support, through computational experiments encompassing a number of technical
platforms. Building on previous research, it implements and tests a novel platform
architecture capable of processing and reasoning with clinical data. The key
components of this platform are the now widely implemented openEHR electronic
health record specifications and Bayesian Belief Networks.
Substantial software implementations are used to explore the integration of
these components, guided and supplemented by input from clinician experts and
using clinical data models derived in hospital settings at Moorfields Eye Hospital.
Data quality and quantity issues are highlighted. Insights thus gained are used to
design and build a novel graph-based representation and processing model for the
clinical data, based on the openEHR specifications. The approach can be
implemented using diverse modern database and platform technologies.
Computational experiments with the platform, using data from two clinical
domains – a preliminary study with published thyroid metabolism data and a
substantial study of cataract surgery – explore fundamental barriers that must be
overcome in intelligent healthcare systems developments for clinical settings. These
have often been neglected, or misunderstood as implementation procedures of
secondary importance. The results confirm that the methods developed have the
potential to overcome a number of these barriers.
The findings lead to proposals for improvements to the openEHR
specifications, in the context of machine learning applications, and in particular for
integrating them with Bayesian Networks. The thesis concludes with a roadmap for
future research, building on progress and findings to date