Dielectrophoretic Manipulation of Particles and Lymphocytes

This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.A particle manipulation and sorting device using the dielectrophoretic (DEP) force is described in this study. The device consists of “ladder-type”, “flip-type” and “oblique rail-type” electrode regions. The ladder-type and rail-type electrodes can generate a DEP force distribution that captures the particles, the DEP force of which is “negative” (repulsion force), in the area located at the center of the electrodes. The particles can then be guided individually along the electrode. In addition to this, the ladder-type electrode can align the particles with equal spacing in the streamwise direction. Using the “flip-type” electrode, which pushes the particles away, in combination with these electrodes, the direction of the particle can be selected with high accuracy, reliability and response. In the first half of this paper, numerical simulation was carried out to calculate the particle motion and evaluate the performance of the ladder-type electrode. Several models were validated to investigate the influences of the non-uniformity of the electric field and the electric interaction of the surface charges and polarizations. Measurement using the high-speed camera was then carried out to investigate the motions of the particles and sorting reliability. The trajectories and the probability density functions of the particles at the inlet and outlet of the electrode region showed that by using these electrodes the particles can be aligned, sorted and guided accurately

A structural analysis of the A5/1 state transition graph

We describe efficient algorithms to analyze the cycle structure of the graph induced by the state transition function of the A5/1 stream cipher used in GSM mobile phones and report on the results of the implementation. The analysis is performed in five steps utilizing HPC clusters, GPGPU and external memory computation. A great reduction of this huge state transition graph of 2^64 nodes is achieved by focusing on special nodes in the first step and removing leaf nodes that can be detected with limited effort in the second step. This step does not break the overall structure of the graph and keeps at least one node on every cycle. In the third step the nodes of the reduced graph are connected by weighted edges. Since the number of nodes is still huge an efficient bitslice approach is presented that is implemented with NVIDIA's CUDA framework and executed on several GPUs concurrently. An external memory algorithm based on the STXXL library and its parallel pipelining feature further reduces the graph in the fourth step. The result is a graph containing only cycles that can be further analyzed in internal memory to count the number and size of the cycles. This full analysis which previously would take months can now be completed within a few days and allows to present structural results for the full graph for the first time. The structure of the A5/1 graph deviates notably from the theoretical results for random mappings.Comment: In Proceedings GRAPHITE 2012, arXiv:1210.611

Real-time lattice boltzmann shallow waters method for breaking wave simulations

We present a new approach for the simulation of surfacebased fluids based in a hybrid formulation of Lattice Boltzmann Method for Shallow Waters and particle systems. The modified LBM can handle arbitrary underlying terrain conditions and arbitrary fluid depth. It also introduces a novel method for tracking dry-wet regions and moving boundaries. Dynamic rigid bodies are also included in our simulations using a two-way coupling. Certain features of the simulation that the LBM can not handle because of its heightfield nature, as breaking waves, are detected and automatically turned into splash particles. Here we use a ballistic particle system, but our hybrid method can handle more complex systems as SPH. Both the LBM and particle systems are implemented in CUDA, although dynamic rigid bodies are simulated in CPU. We show the effectiveness of our method with various examples which achieve real-time on consumer-level hardware.Peer ReviewedPostprint (author's final draft

Space and Time Efficient Parallel Graph Decomposition, Clustering, and Diameter Approximation

We develop a novel parallel decomposition strategy for unweighted, undirected graphs, based on growing disjoint connected clusters from batches of centers progressively selected from yet uncovered nodes. With respect to similar previous decompositions, our strategy exercises a tighter control on both the number of clusters and their maximum radius. We present two important applications of our parallel graph decomposition: (1) $k$-center clustering approximation; and (2) diameter approximation. In both cases, we obtain algorithms which feature a polylogarithmic approximation factor and are amenable to a distributed implementation that is geared for massive (long-diameter) graphs. The total space needed for the computation is linear in the problem size, and the parallel depth is substantially sublinear in the diameter for graphs with low doubling dimension. To the best of our knowledge, ours are the first parallel approximations for these problems which achieve sub-diameter parallel time, for a relevant class of graphs, using only linear space. Besides the theoretical guarantees, our algorithms allow for a very simple implementation on clustered architectures: we report on extensive experiments which demonstrate their effectiveness and efficiency on large graphs as compared to alternative known approaches.Comment: 14 page