Earthquake Engineering

The book Earthquake Engineering - From Engineering Seismology to Optimal Seismic Design of Engineering Structures contains fifteen chapters written by researchers and experts in the fields of earthquake and structural engineering. This book provides the state-of-the-art on recent progress in the field of seimology, earthquake engineering and structural engineering. The book should be useful to graduate students, researchers and practicing structural engineers. It deals with seismicity, seismic hazard assessment and system oriented emergency response for abrupt earthquake disaster, the nature and the components of strong ground motions and several other interesting topics, such as dam-induced earthquakes, seismic stability of slopes and landslides. The book also tackles the dynamic response of underground pipes to blast loads, the optimal seismic design of RC multi-storey buildings, the finite-element analysis of cable-stayed bridges under strong ground motions and the acute psychiatric trauma intervention due to earthquakes

Climbing and Walking Robots

Nowadays robotics is one of the most dynamic fields of scientific researches. The shift of robotics researches from manufacturing to services applications is clear. During the last decades interest in studying climbing and walking robots has been increased. This increasing interest has been in many areas that most important ones of them are: mechanics, electronics, medical engineering, cybernetics, controls, and computers. Today’s climbing and walking robots are a combination of manipulative, perceptive, communicative, and cognitive abilities and they are capable of performing many tasks in industrial and non- industrial environments. Surveillance, planetary exploration, emergence rescue operations, reconnaissance, petrochemical applications, construction, entertainment, personal services, intervention in severe environments, transportation, medical and etc are some applications from a very diverse application fields of climbing and walking robots. By great progress in this area of robotics it is anticipated that next generation climbing and walking robots will enhance lives and will change the way the human works, thinks and makes decisions. This book presents the state of the art achievments, recent developments, applications and future challenges of climbing and walking robots. These are presented in 24 chapters by authors throughtot the world The book serves as a reference especially for the researchers who are interested in mobile robots. It also is useful for industrial engineers and graduate students in advanced study

Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues

This volume contains 17 short review articles classified into 3 parts. Part I consists of 7 articles dealing with basic aspects of contractile mechanism in skeletal and smooth muscle cells and also function of melanocytes having many properties common to those of smooth muscles. Part II and Part III contain articles dealing with pathological aspects of cardiac and smooth muscle cell functions, and dealing with factors influencing structure and function of cardiac and smooth muscle cells and tissues. The Editor believes that these articles are stimulating and informative for readers interested in basic, pathological and clinical aspects of muscle cells and tissues

Collective Behaviour: From Cells to Humans

Living in organised groups is a strategy that can be observed in a multitude of diverse species. Among such species, the behaviour of an individual on their own is not the same as within a group: the environment is modified by the presence of more subjects, individuals interact with each other, and from those interactions complex patterns of behaviour can emerge. Some species of animals almost exclusively exist as groups, and as a consequence, studying them in a social context is the only way to understand their behaviour in nature. This is the idea that drives all the research presented in this thesis: the particular behaviour exhibited by the group is so robust that it will emerge even in a very simplified environment. By observing the individual and the group in those simplified experimental conditions, it is possible to deduce rules that might govern the interaction. The importance of interactions in the group’s behaviour can then be demonstrated by implementing a computer model of agents following those rules and comparing it with natural and experimental behaviour. This thesis presents different examples of such analyses, and gives illustrations of the range of questions that can be answered through this method. Groups of stem cells, juvenile sea bass and human beings were successively observed and tracked in suitable environments, with or without perturbation. The data extracted from those experiments were then processed so as to correct recording errors, and individual and collective behaviours were derived from those data, returning new insights on the nature of the interaction at the individual level, their consequences at the global level, as well as the effects of the interaction on both. Finally, I present the computer models derived from those analyses. Many systems in nature share this property of global behaviours emerging from deterministic local interaction, and as a consequence studies of this kind could shed light on important questions, of which cancer treatment, ocean acidification and human organisations are but a few examples

Mass Spectrometry-Based Proteomics Analysis of the Matrix Microenvironment in Pluripotent Stem Cell Culture

The stem cell microenvironment contains soluble factors, support cells, and components of the extracellular matrix (ECM) that combine to effect cellular behavior. Mass spectrometry based proteomics offers the opportunity to directly assay components of extracellular microenvironments, thereby providing a sensitive means for obtaining insight into the stem cell niche. In this study we present the generation and analysis of human embryonic stem cell (hESC) and human induced pluripotent stem cell (hiPSC) matrix microenvironments using an MS-based proteomics approach. One of the primary limitations in the proteomics analysis of hESCs and hiPSCs is the reproducible generation of sufficient cell numbers amenable to experimentation. In Chapter 2 we develop reliable methods for the maintenance and proliferation of hESCs in metabolic labeling medium for use in stable isotope labeling with amino acids in cell culture (SILAC) experiments. Previously, the application of SILAC with hESCs was hindered by the use of medium insufficient for their reproducible culture and the problematic conversion of isotopically labeled arginine to proline. To address these issues, we demonstrate the culture of hESCs, hiPSCs, and mouse ESCs in SILAC conditions using a serum-replacement mixture and alternatively in defined medium. In these optimized conditions we show that the problematic conversion of arginine to proline can be eliminated through the simple addition of exogenous proline to the culture medium. Within the in vitro microenvironment, the ECM plays a significant role in the maintenance and regulation of hESCs and hiPSCs. In order to better understand the communication between hESCs and hiPSCs and the extracellular matrix, we focused our investigation on this portion of the microenvironment. To facilitate the proteomic analysis of complex ECM mixtures, in Chapter 3 we describe methods for the fractionation and MS-based proteomics analysis of these matrices. Application to a variety of cell-derived and recombinant growth matrices demonstrates not only the effectiveness of our methods, but also the utility of directly assaying matrices used in hESC culture for the determination of factors beneficial for the maintenance of self-renewal and pluripotency. Through combination of the SILAC growth (Chapter 2) and matrix analysis (Chapter 3) methods, the protein compositions of conditioned matrices from multiple pluripotent stem cell lines are determined (Chapter 4). Within these matrices, numerous antagonists of core pluripotency pathways are identified, such as soluble frizzled related protein (sFRP) 1 and 2. In Chapter 5 we focus on characterizing the functions of sFRP1 and sFRP2 in hESC self-renewal and pluripotency. Taken together, the work presented here illustrates the utility of assaying interactions between stem cells and their matrix microenvironment for the determination of pathways involved in the regulation of the pluripotent phenotype

The social organization of the Azande of the Bahr-el-Ghazal province of the Anglo-Egyptian Sudan

This thesis represents part of my Ethnological research carries out in the Anglo-Egyptian Sudan in the years 1926 and 1927. After having worked for three months in the area between the White and Blue Niles, mainly amongst the Ingassana People of the Tabi Hills, and later for some seven weeks on the West Bank of the Nule, amongst the Moro Peoples, I arrived in that part of the Bahr-el-Ghazal Province which is inhabited by the Azande towards the end of March 1927. I left for England at the end of August, thus completing a residence of five months amongst the Azande. The Thesis is arranged in two books. The first book is a condensed analysis of the structure of Zande society. In the second book I have taken native customer or institutions, divination, magic, dancing and obscene songs, and I have en-deavoured to interpret them by showing their contexts, associa-tions and functions. It is by the method exemplified in the second book of this thesis that I hope to explain one by one the institutions of the Azande. In the parts on magic and obscenity I have used the comparative method of analysis. It is this method which must eventually be applied to all institu-tions if Social Anthropology is to put forward general state-ments, or laws, and so take its place in the ranks of other inductive sciences

Collected Papers (on Neutrosophic Theory and Applications), Volume VI

This sixth volume of Collected Papers includes 74 papers comprising 974 pages on (theoretic and applied) neutrosophics, written between 2015-2021 by the author alone or in collaboration with the following 121 co-authors from 19 countries: Mohamed Abdel-Basset, Abdel Nasser H. Zaied, Abduallah Gamal, Amir Abdullah, Firoz Ahmad, Nadeem Ahmad, Ahmad Yusuf Adhami, Ahmed Aboelfetouh, Ahmed Mostafa Khalil, Shariful Alam, W. Alharbi, Ali Hassan, Mumtaz Ali, Amira S. Ashour, Asmaa Atef, Assia Bakali, Ayoub Bahnasse, A. A. Azzam, Willem K.M. Brauers, Bui Cong Cuong, Fausto Cavallaro, Ahmet Çevik, Robby I. Chandra, Kalaivani Chandran, Victor Chang, Chang Su Kim, Jyotir Moy Chatterjee, Victor Christianto, Chunxin Bo, Mihaela Colhon, Shyamal Dalapati, Arindam Dey, Dunqian Cao, Fahad Alsharari, Faruk Karaaslan, Aleksandra Fedajev, Daniela Gîfu, Hina Gulzar, Haitham A. El-Ghareeb, Masooma Raza Hashmi, Hewayda El-Ghawalby, Hoang Viet Long, Le Hoang Son, F. Nirmala Irudayam, Branislav Ivanov, S. Jafari, Jeong Gon Lee, Milena Jevtić, Sudan Jha, Junhui Kim, Ilanthenral Kandasamy, W.B. Vasantha Kandasamy, Darjan Karabašević, Songül Karabatak, Abdullah Kargın, M. Karthika, Ieva Meidute-Kavaliauskiene, Madad Khan, Majid Khan, Manju Khari, Kifayat Ullah, K. Kishore, Kul Hur, Santanu Kumar Patro, Prem Kumar Singh, Raghvendra Kumar, Tapan Kumar Roy, Malayalan Lathamaheswari, Luu Quoc Dat, T. Madhumathi, Tahir Mahmood, Mladjan Maksimovic, Gunasekaran Manogaran, Nivetha Martin, M. Kasi Mayan, Mai Mohamed, Mohamed Talea, Muhammad Akram, Muhammad Gulistan, Raja Muhammad Hashim, Muhammad Riaz, Muhammad Saeed, Rana Muhammad Zulqarnain, Nada A. Nabeeh, Deivanayagampillai Nagarajan, Xenia Negrea, Nguyen Xuan Thao, Jagan M. Obbineni, Angelo de Oliveira, M. Parimala, Gabrijela Popovic, Ishaani Priyadarshini, Yaser Saber, Mehmet Șahin, Said Broumi, A. A. Salama, M. Saleh, Ganeshsree Selvachandran, Dönüș Șengür, Shio Gai Quek, Songtao Shao, Dragiša Stanujkić, Surapati Pramanik, Swathi Sundari Sundaramoorthy, Mirela Teodorescu, Selçuk Topal, Muhammed Turhan, Alptekin Ulutaș, Luige Vlădăreanu, Victor Vlădăreanu, Ştefan Vlăduţescu, Dan Valeriu Voinea, Volkan Duran, Navneet Yadav, Yanhui Guo, Naveed Yaqoob, Yongquan Zhou, Young Bae Jun, Xiaohong Zhang, Xiao Long Xin, Edmundas Kazimieras Zavadskas