Designing Light Filters to Detect Skin Using a Low-powered Sensor

Detection of nudity in photos and videos, especially prior to uploading to the internet, is vital to solving many problems related to adolescent sexting, the distribution of child pornography, and cyber-bullying. The problem with using nudity detection algorithms as a means to combat these problems is that: 1) it implies that a digitized nude photo of a minor already exists (i.e., child pornography), and 2) there are real ethical and legal concerns around the distribution and processing of child pornography. Once a camera captures an image, that image is no longer secure. Therefore, we need to develop new privacy-preserving solutions that prevent the digital capture of nude imagery of minors. My research takes a first step in trying to accomplish this long-term goal: In this thesis, I examine the feasibility of using a low-powered sensor to detect skin dominance (defined as an image comprised of 50% or more of human skin tone) in a visual scene. By designing four custom light filters to enhance the digital information extracted from 300 scenes captured with the sensor (without digitizing high-fidelity visual features), I was able to accurately detect a skin dominant scene with 83.7% accuracy, 83% precision, and 85% recall. The long-term goal to be achieved in the future is to design a low-powered vision sensor that can be mounted on a digital camera lens on a teen\u27s mobile device to detect and/or prevent the capture of nude imagery. Thus, I discuss the limitations of this work toward this larger goal, as well as future research directions

Deep Insights of Deepfake Technology : A Review

Under the aegis of computer vision and deep learning technology, a new emerging techniques has introduced that anyone can make highly realistic but fake videos, images even can manipulates the voices. This technology is widely known as Deepfake Technology. Although it seems interesting techniques to make fake videos or image of something or some individuals but it could spread as misinformation via internet. Deepfake contents could be dangerous for individuals as well as for our communities, organizations, countries religions etc. As Deepfake content creation involve a high level expertise with combination of several algorithms of deep learning, it seems almost real and genuine and difficult to differentiate. In this paper, a wide range of articles have been examined to understand Deepfake technology more extensively. We have examined several articles to find some insights such as what is Deepfake, who are responsible for this, is there any benefits of Deepfake and what are the challenges of this technology. We have also examined several creation and detection techniques. Our study revealed that although Deepfake is a threat to our societies, proper measures and strict regulations could prevent this

There Is a Digital Art History

In this paper, we revisit Johanna Drucker's question, "Is there a digital art history?" -- posed exactly a decade ago -- in the light of the emergence of large-scale, transformer-based vision models. While more traditional types of neural networks have long been part of digital art history, and digital humanities projects have recently begun to use transformer models, their epistemic implications and methodological affordances have not yet been systematically analyzed. We focus our analysis on two main aspects that, together, seem to suggest a coming paradigm shift towards a "digital" art history in Drucker's sense. On the one hand, the visual-cultural repertoire newly encoded in large-scale vision models has an outsized effect on digital art history. The inclusion of significant numbers of non-photographic images allows for the extraction and automation of different forms of visual logics. Large-scale vision models have "seen" large parts of the Western visual canon mediated by Net visual culture, and they continuously solidify and concretize this canon through their already widespread application in all aspects of digital life. On the other hand, based on two technical case studies of utilizing a contemporary large-scale visual model to investigate basic questions from the fields of art history and urbanism, we suggest that such systems require a new critical methodology that takes into account the epistemic entanglement of a model and its applications. This new methodology reads its corpora through a neural model's training data, and vice versa: the visual ideologies of research datasets and training datasets become entangled

Online child sexual exploitation: a new MIS challenge

© 2021, Association for Information Systems. All rights reserved. This paper deals with the difficult yet increasingly important MIS phenomenon of online child sexual exploitation (online CSE). Through the use of secondary and publicly available data from the Federal Bureau of Investigation, as well as primary data from a cybercrime police unit in the United Kingdom, this study takes a grounded theory approach and organizes the role that technologies and social actors play in shaping online CSE. The paper contributes to IS theory by providing a consolidated model for online CSE, which we call the technology and imagery dimensions model. This model combines the staging of the phenomenon and the key dimensions that depict how the use of technology and imagery both fuels and defuses the phenomenon. In informing the construction of the model, the paper extracts, organizes, and generalizes the affordances of technology and discusses the role of information systems in detecting online CSE

Improving treatment of glioblastoma: new insights in targeting cancer stem cells effectively

Glioblastoma is the most common primary malignant brain tumour in the adult population. Despite multimodality treatment with surgery, radiotherapy and chemotherapy, outcomes are very poor, with less than 15% of patients alive after two years. Increasing evidence suggests that glioblastoma stem cells (GSCs) are likely to play an important role in the biology of this disease and are involved in treatment resistance and tumour recurrence following standard therapy. My thesis aims to address two main aspects of this research area: 1) optimization of methods to evaluate treatment responses of GSCs and their differentiated counterparts (non-GSCs), with a particular focus on a tissue culture model that resembles more closely the tumoral niche; 2) characterization of cell division and centrosome cycle of GSCs, investigating possible differences between these cells and non-GSCs, that would allow the identification of targets for new therapeutic strategies against glioblastomas. In the first part of my project, I optimized a clonogenic survival assay, to compare sensitivity of GSCs and non-GSCs to various treatments, and I developed the use of a 3-dimentional tissue culture system, that allows analysis of features and radiation responses of these two subpopulations in the presence of specific microenvironmental factors from the tumoral niche. In the second part, I show that GSCs display mitotic spindle abnormalities more frequently than non-GSCs and that they have distinctive features with regards to the centrosome cycle. I also demonstrate that GSCs are more sensitive than non-GSCs to subtle changes in Aurora kinase A activity, which result in a rapid increase in polyploidy and subsequently in senescence, with a consistent reduction in clonogenic survival. Based on these findings, I propose that kinases involved in the centrosome cycle need to be explored as a novel strategy to target GSCs effectively and improve outcomes of glioblastoma patients

Current Trends in Cancer Nanotheranostics: Metallic, Polymeric, and Lipid-Based Systems

Theranostics has emerged in recent years to provide an efficient and safer alternative in cancer management. This review presents an updated description of nanotheranostic formulations under development for skin cancer (including melanoma), head and neck, thyroid, breast, gynecologic, prostate, and colon cancers, brain-related cancer, and hepatocellular carcinoma. With this focus, we appraised the clinical advantages and drawbacks of metallic, polymeric, and lipid-based nanosystems, such as low invasiveness, low toxicity to the surrounding healthy tissues, high precision, deeper tissue penetration, and dosage adjustment in a real-time setting. Particularly recognizing the increased complexity and multimodality in this area, multifunctional hybrid nanoparticles, comprising different nanomaterials and functionalized with targeting moieties and/or anticancer drugs, present the best characteristics for theranostics. Several examples, focusing on their design, composition, imaging and treatment modalities, and in vitro and in vivo characterization, are detailed herein. Briefly, all studies followed a common trend in the design of these theranostics modalities, such as the use of materials and/or drugs that share both inherent imaging (e.g., contrast agents) and therapeutic properties (e.g., heating or production reactive oxygen species). This rationale allows one to apparently overcome the heterogeneity, complexity, and harsh conditions of tumor microenvironments, leading to the development of successful targeted therapies.The authors acknowledge Fundação para a Ciência e a Tecnologia (FCT) for financial support through Projects UID/DTP/04138/2013, PTDC/MED-QUI/31721/2017 and for financial support through PhD fellowship SFRH/BD/117586/2016.info:eu-repo/semantics/publishedVersio

Tracking Strain-Specific Morphogenesis and Angiogenesis of Murine Calvaria with Large-Scale Optoacoustic and Ultrasound Microscopy

Skull bone development is a dynamic and well-coordinated process playing a key role in maturation and maintenance of the bone marrow (BM), fracture healing, and progression of diseases such as osteoarthritis or osteoporosis. At present, dynamic transformation of the growing bone (osteogenesis) as well as its vascularization (angiogenesis) remain largely unexplored due to the lack of suitable in vivo imaging techniques capable of noninvasive visualization of the whole developing calvaria at capillary-level resolution. We present a longitudinal study on skull bone development using ultrasound-aided large-scale optoacoustic microscopy (U-LSOM). Skull bone morphogenesis and microvascular growth patterns were monitored in three common mouse strains (C57BL/6J, CD-1, and Athymic Nude-Foxn1nu) at the whole-calvaria scale over a 3-month period. Strain-specific differences in skull development were revealed by quantitative analysis of bone and vessel parameters, indicating the coupling between angiogenesis and osteogenesis during skull bone growth in a minimally invasive and label-free manner. The method further enabled identifying BM-specific sinusoidal vessels, and superficial skull vessels penetrating into BM compartments. Our approach furnishes a new high-throughput longitudinal in vivo imaging platform to study morphological and vascular skull alterations in health and disease, shedding light on the critical links between blood vessel formation, skull growth, and regeneration. © 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR)

Aesthetic surgery and the expressive body

In this paper we explore the relation between bodies and selves evident in the narratives surrounding aesthetic surgery. In much feminist work on aesthetic surgery such narratives have been discussed in terms of the normalising consequences of the objectifying, homogenising, cosmetic gaze. These discussions stress the ways in which we model our bodies, under the gaze of others, in order to conform to social norms. Such an objectified body is contrasted with the subjective body; the body –for –the self. In this paper, however, we wish to make sense of the narratives surrounding such surgery by invoking the expressive body, which fits on neither side of this binary. We wish to explore how the modification of the body’s anatomical features (physiology) are taken to be a modification of its expressive possibilities, and therefore as modifications of possibilities for inter-subjective relations with others. It is such expressive possibilities, which, we suggest, underlie decisions to undergo surgical procedures. The possibility of modification of the expressive possibilities of the body, by the modification of its anatomical features, rests on the social imaginaries attached to anatomical features. In the context of such imaginaries individual decisions to undergo or promote surgery can be both intelligible and potentially empowering. However, the social consequences of such acts are an increasing normalisation of the ‘body under the knife’ and an intolerance of bodily difference. This, we suggest, can only be changed by a re-visioning of bodily imaginaries so that expressive possibilities can be experienced across bodies with a range of physiological features