A semiparametric regression model for paired longitudinal outcomes with application in childhood blood pressure development

This research examines the simultaneous influences of height and weight on longitudinally measured systolic and diastolic blood pressure in children. Previous studies have shown that both height and weight are positively associated with blood pressure. In children, however, the concurrent increases of height and weight have made it all but impossible to discern the effect of height from that of weight. To better understand these influences, we propose to examine the joint effect of height and weight on blood pressure. Bivariate thin plate spline surfaces are used to accommodate the potentially nonlinear effects as well as the interaction between height and weight. Moreover, we consider a joint model for paired blood pressure measures, that is, systolic and diastolic blood pressure, to account for the underlying correlation between the two measures within the same individual. The bivariate spline surfaces are allowed to vary across different groups of interest. We have developed related model fitting and inference procedures. The proposed method is used to analyze data from a real clinical investigation.Comment: Published in at http://dx.doi.org/10.1214/12-AOAS567 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

Extreme-Value Copulas

Being the limits of copulas of componentwise maxima in independent random samples, extreme-value copulas can be considered to provide appropriate models for the dependence structure between rare events. Extreme-value copulas not only arise naturally in the domain of extreme-value theory, they can also be a convenient choice to model general positive dependence structures. The aim of this survey is to present the reader with the state-of-the-art in dependence modeling via extreme-value copulas. Both probabilistic and statistical issues are reviewed, in a nonparametric as well as a parametric context.Comment: 20 pages, 3 figures. Minor revision, typos corrected. To appear in F. Durante, W. Haerdle, P. Jaworski, and T. Rychlik (editors) "Workshop on Copula Theory and its Applications", Lecture Notes in Statistics -- Proceedings, Springer 201

EI: A Program for Ecological Inference

The program EI provides a method of inferring individual behavior from aggregate data. It implements the statistical procedures, diagnostics, and graphics from the book A Solution to the Ecological Inference Problem: Reconstructing Individual Behavior from Aggregate Data (King'97). Ecological inference, as traditionally defined, is the process of using aggregate (i.e., "ecological") data to infer discrete individual-level relationships of interest when individual-level data are not available. Ecological inferences are required in political science research when individual-level surveys are unavailable (e.g., local or comparative electoral politics), unreliable (racial politics), insufficient (political geography), or infeasible (political history). They are also required in numerous areas of ma jor significance in public policy (e.g., for applying the Voting Rights Act) and other academic disciplines ranging from epidemiology and marketing to sociology and quantitative history.

Approximate Bayesian inference in semiparametric copula models

We describe a simple method for making inference on a functional of a multivariate distribution. The method is based on a copula representation of the multivariate distribution and it is based on the properties of an Approximate Bayesian Monte Carlo algorithm, where the proposed values of the functional of interest are weighed in terms of their empirical likelihood. This method is particularly useful when the "true" likelihood function associated with the working model is too costly to evaluate or when the working model is only partially specified.Comment: 27 pages, 18 figure