Dynamic Analysis of X-ray Angiography for Image-Guided Coronary Interventions

Percutaneous coronary intervention (PCI) is a minimally-invasive procedure for treating patients with coronary artery disease. PCI is typically performed with image guidance using X-ray angiograms (XA) in which coronary arter

Optical flow-based vascular respiratory motion compensation

This paper develops a new vascular respiratory motion compensation algorithm, Motion-Related Compensation (MRC), to conduct vascular respiratory motion compensation by extrapolating the correlation between invisible vascular and visible non-vascular. Robot-assisted vascular intervention can significantly reduce the radiation exposure of surgeons. In robot-assisted image-guided intervention, blood vessels are constantly moving/deforming due to respiration, and they are invisible in the X-ray images unless contrast agents are injected. The vascular respiratory motion compensation technique predicts 2D vascular roadmaps in live X-ray images. When blood vessels are visible after contrast agents injection, vascular respiratory motion compensation is conducted based on the sparse Lucas-Kanade feature tracker. An MRC model is trained to learn the correlation between vascular and non-vascular motions. During the intervention, the invisible blood vessels are predicted with visible tissues and the trained MRC model. Moreover, a Gaussian-based outlier filter is adopted for refinement. Experiments on in-vivo data sets show that the proposed method can yield vascular respiratory motion compensation in 0.032 sec, with an average error 1.086 mm. Our real-time and accurate vascular respiratory motion compensation approach contributes to modern vascular intervention and surgical robots.Comment: This manuscript has been accepted by IEEE Robotics and Automation Letter

Dynamic coronary roadmapping via catheter tip tracking in X-ray fluoroscopy with deep learning based Bayesian filtering

Percutaneous coronary intervention (PCI) is typically performed with image guidance using X-ray angiograms in which coronary arteries are opacified with X-ray opaque contrast agents. Interventional cardiologists typically navigate instruments using non-contrast-enhanced fluoroscopic images, since higher use of contrast agents increases the risk of kidney failure. When using fluoroscopic images, the interventional cardiologist needs to rely on a mental anatomical reconstruction. This paper reports on the development of a novel dynamic coronary roadmapping approach for improving visual feedback and reducing contrast use during PCI. The approach compensates cardiac and respiratory induced vessel motion by ECG alignment and catheter tip tracking in X-ray fluoroscopy, respectively. In particular, for accurate and robust tracking of the catheter tip, we proposed a new deep learning based Bayesian filtering method that integrates the detection outcome of a convolutional neural network and the motion estimation between frames using a particle filtering framework. The proposed roadmapping and tracking approaches were validated on clinical X-ray images, achieving accurate performance on both catheter tip tracking and dynamic coronary roadmapping experiments. In addition, our approach runs in real-time on a computer with a single GPU and has the potential to be integrated into the clinical workflow of PCI procedures, providing cardiologists with visual guidance during interventions without the need of extra use of contrast agent.Accepted Author ManuscriptOptical and Laser Remote Sensin