DPVis: Visual Analytics with Hidden Markov Models for Disease Progression Pathways

Clinical researchers use disease progression models to understand patient status and characterize progression patterns from longitudinal health records. One approach for disease progression modeling is to describe patient status using a small number of states that represent distinctive distributions over a set of observed measures. Hidden Markov models (HMMs) and its variants are a class of models that both discover these states and make inferences of health states for patients. Despite the advantages of using the algorithms for discovering interesting patterns, it still remains challenging for medical experts to interpret model outputs, understand complex modeling parameters, and clinically make sense of the patterns. To tackle these problems, we conducted a design study with clinical scientists, statisticians, and visualization experts, with the goal to investigate disease progression pathways of chronic diseases, namely type 1 diabetes (T1D), Huntington's disease, Parkinson's disease, and chronic obstructive pulmonary disease (COPD). As a result, we introduce DPVis which seamlessly integrates model parameters and outcomes of HMMs into interpretable and interactive visualizations. In this study, we demonstrate that DPVis is successful in evaluating disease progression models, visually summarizing disease states, interactively exploring disease progression patterns, and building, analyzing, and comparing clinically relevant patient subgroups.Comment: to appear at IEEE Transactions on Visualization and Computer Graphic

Video semantic content analysis framework based on ontology combined MPEG-7

The rapid increase in the available amount of video data is creating a growing demand for efficient methods for understanding and managing it at the semantic level. New multimedia standard, MPEG-7, provides the rich functionalities to enable the generation of audiovisual descriptions and is expressed solely in XML Schema which provides little support for expressing semantic knowledge. In this paper, a video semantic content analysis framework based on ontology combined MPEG-7 is presented. Domain ontology is used to define high level semantic concepts and their relations in the context of the examined domain. MPEG-7 metadata terms of audiovisual descriptions and video content analysis algorithms are expressed in this ontology to enrich video semantic analysis. OWL is used for the ontology description. Rules in Description Logic are defined to describe how low-level features and algorithms for video analysis should be applied according to different perception content. Temporal Description Logic is used to describe the semantic events, and a reasoning algorithm is proposed for events detection. The proposed framework is demonstrated in sports video domain and shows promising results

Video semantic content analysis based on ontology

The rapid increase in the available amount of video data is creating a growing demand for efficient methods for understanding and managing it at the semantic level. New multimedia standards, such as MPEG-4 and MPEG-7, provide the basic functionalities in order to manipulate and transmit objects and metadata. But importantly, most of the content of video data at a semantic level is out of the scope of the standards. In this paper, a video semantic content analysis framework based on ontology is presented. Domain ontology is used to define high level semantic concepts and their relations in the context of the examined domain. And low-level features (e.g. visual and aural) and video content analysis algorithms are integrated into the ontology to enrich video semantic analysis. OWL is used for the ontology description. Rules in Description Logic are defined to describe how features and algorithms for video analysis should be applied according to different perception content and low-level features. Temporal Description Logic is used to describe the semantic events, and a reasoning algorithm is proposed for events detection. The proposed framework is demonstrated in a soccer video domain and shows promising results