Patch-based Convolutional Neural Network for Whole Slide Tissue Image Classification

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently computationally impossible. The differentiation of cancer subtypes is based on cellular-level visual features observed on image patch scale. Therefore, we argue that in this situation, training a patch-level classifier on image patches will perform better than or similar to an image-level classifier. The challenge becomes how to intelligently combine patch-level classification results and model the fact that not all patches will be discriminative. We propose to train a decision fusion model to aggregate patch-level predictions given by patch-level CNNs, which to the best of our knowledge has not been shown before. Furthermore, we formulate a novel Expectation-Maximization (EM) based method that automatically locates discriminative patches robustly by utilizing the spatial relationships of patches. We apply our method to the classification of glioma and non-small-cell lung carcinoma cases into subtypes. The classification accuracy of our method is similar to the inter-observer agreement between pathologists. Although it is impossible to train CNNs on WSIs, we experimentally demonstrate using a comparable non-cancer dataset of smaller images that a patch-based CNN can outperform an image-based CNN

Hybrid image representation methods for automatic image annotation: a survey

In most automatic image annotation systems, images are represented with low level features using either global methods or local methods. In global methods, the entire image is used as a unit. Local methods divide images into blocks where fixed-size sub-image blocks are adopted as sub-units; or into regions by using segmented regions as sub-units in images. In contrast to typical automatic image annotation methods that use either global or local features exclusively, several recent methods have considered incorporating the two kinds of information, and believe that the combination of the two levels of features is beneficial in annotating images. In this paper, we provide a survey on automatic image annotation techniques according to one aspect: feature extraction, and, in order to complement existing surveys in literature, we focus on the emerging image annotation methods: hybrid methods that combine both global and local features for image representation

A robust and efficient video representation for action recognition

This paper introduces a state-of-the-art video representation and applies it to efficient action recognition and detection. We first propose to improve the popular dense trajectory features by explicit camera motion estimation. More specifically, we extract feature point matches between frames using SURF descriptors and dense optical flow. The matches are used to estimate a homography with RANSAC. To improve the robustness of homography estimation, a human detector is employed to remove outlier matches from the human body as human motion is not constrained by the camera. Trajectories consistent with the homography are considered as due to camera motion, and thus removed. We also use the homography to cancel out camera motion from the optical flow. This results in significant improvement on motion-based HOF and MBH descriptors. We further explore the recent Fisher vector as an alternative feature encoding approach to the standard bag-of-words histogram, and consider different ways to include spatial layout information in these encodings. We present a large and varied set of evaluations, considering (i) classification of short basic actions on six datasets, (ii) localization of such actions in feature-length movies, and (iii) large-scale recognition of complex events. We find that our improved trajectory features significantly outperform previous dense trajectories, and that Fisher vectors are superior to bag-of-words encodings for video recognition tasks. In all three tasks, we show substantial improvements over the state-of-the-art results

Multi-Cue Structure Preserving MRF for Unconstrained Video Segmentation

Video segmentation is a stepping stone to understanding video context. Video segmentation enables one to represent a video by decomposing it into coherent regions which comprise whole or parts of objects. However, the challenge originates from the fact that most of the video segmentation algorithms are based on unsupervised learning due to expensive cost of pixelwise video annotation and intra-class variability within similar unconstrained video classes. We propose a Markov Random Field model for unconstrained video segmentation that relies on tight integration of multiple cues: vertices are defined from contour based superpixels, unary potentials from temporal smooth label likelihood and pairwise potentials from global structure of a video. Multi-cue structure is a breakthrough to extracting coherent object regions for unconstrained videos in absence of supervision. Our experiments on VSB100 dataset show that the proposed model significantly outperforms competing state-of-the-art algorithms. Qualitative analysis illustrates that video segmentation result of the proposed model is consistent with human perception of objects

A Study of Actor and Action Semantic Retention in Video Supervoxel Segmentation

Existing methods in the semantic computer vision community seem unable to deal with the explosion and richness of modern, open-source and social video content. Although sophisticated methods such as object detection or bag-of-words models have been well studied, they typically operate on low level features and ultimately suffer from either scalability issues or a lack of semantic meaning. On the other hand, video supervoxel segmentation has recently been established and applied to large scale data processing, which potentially serves as an intermediate representation to high level video semantic extraction. The supervoxels are rich decompositions of the video content: they capture object shape and motion well. However, it is not yet known if the supervoxel segmentation retains the semantics of the underlying video content. In this paper, we conduct a systematic study of how well the actor and action semantics are retained in video supervoxel segmentation. Our study has human observers watching supervoxel segmentation videos and trying to discriminate both actor (human or animal) and action (one of eight everyday actions). We gather and analyze a large set of 640 human perceptions over 96 videos in 3 different supervoxel scales. Furthermore, we conduct machine recognition experiments on a feature defined on supervoxel segmentation, called supervoxel shape context, which is inspired by the higher order processes in human perception. Our ultimate findings suggest that a significant amount of semantics have been well retained in the video supervoxel segmentation and can be used for further video analysis.Comment: This article is in review at the International Journal of Semantic Computin

A Supervised Neural Autoregressive Topic Model for Simultaneous Image Classification and Annotation

Topic modeling based on latent Dirichlet allocation (LDA) has been a framework of choice to perform scene recognition and annotation. Recently, a new type of topic model called the Document Neural Autoregressive Distribution Estimator (DocNADE) was proposed and demonstrated state-of-the-art performance for document modeling. In this work, we show how to successfully apply and extend this model to the context of visual scene modeling. Specifically, we propose SupDocNADE, a supervised extension of DocNADE, that increases the discriminative power of the hidden topic features by incorporating label information into the training objective of the model. We also describe how to leverage information about the spatial position of the visual words and how to embed additional image annotations, so as to simultaneously perform image classification and annotation. We test our model on the Scene15, LabelMe and UIUC-Sports datasets and show that it compares favorably to other topic models such as the supervised variant of LDA.Comment: 13 pages, 5 figure