2,363,011 research outputs found

    Robust Likelihood-Based Survival Modeling with Microarray Data

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    Gene expression data can be associated with various clinical outcomes. In particular, these data can be of importance in discovering survival-associated genes for medical applications. As alternatives to traditional statistical methods, sophisticated methods and software programs have been developed to overcome the high-dimensional difficulty of microarray data. Nevertheless, new algorithms and software programs are needed to include practical functions such as the discovery of multiple sets of survival-associated genes and the incorporation of risk factors, and to use in the R environment which many statisticians are familiar with. For survival modeling with microarray data, we have developed a software program (called rbsurv) which can be used conveniently and interactively in the R environment. This program selects survival-associated genes based on the partial likelihood of the Cox model and separates training and validation sets of samples for robustness. It can discover multiple sets of genes by iterative forward selection rather than one large set of genes. It can also allow adjustment for risk factors in microarray survival modeling. This software package, the rbsurv package, can be used to discover survival-associated genes with microarray data conveniently.

    Stigmergy-based modeling to discover urban activity patterns from positioning data

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    Positioning data offer a remarkable source of information to analyze crowds urban dynamics. However, discovering urban activity patterns from the emergent behavior of crowds involves complex system modeling. An alternative approach is to adopt computational techniques belonging to the emergent paradigm, which enables self-organization of data and allows adaptive analysis. Specifically, our approach is based on stigmergy. By using stigmergy each sample position is associated with a digital pheromone deposit, which progressively evaporates and aggregates with other deposits according to their spatiotemporal proximity. Based on this principle, we exploit positioning data to identify high density areas (hotspots) and characterize their activity over time. This characterization allows the comparison of dynamics occurring in different days, providing a similarity measure exploitable by clustering techniques. Thus, we cluster days according to their activity behavior, discovering unexpected urban activity patterns. As a case study, we analyze taxi traces in New York City during 2015

    Data analytics for modeling and visualizing attack behaviors: A case study on SSH brute force attacks

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    In this research, we explore a data analytics based approach for modeling and visualizing attack behaviors. To this end, we employ Self-Organizing Map and Association Rule Mining algorithms to analyze and interpret the behaviors of SSH brute force attacks and SSH normal traffic as a case study. The experimental results based on four different data sets show that the patterns extracted and interpreted from the SSH brute force attack data sets are similar to each other but significantly different from those extracted from the SSH normal traffic data sets. The analysis of the attack traffic provides insight into behavior modeling for brute force SSH attacks. Furthermore, this sheds light into how data analytics could help in modeling and visualizing attack behaviors in general in terms of data acquisition and feature extraction
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