60,374 research outputs found
Power Management Techniques for Data Centers: A Survey
With growing use of internet and exponential growth in amount of data to be
stored and processed (known as 'big data'), the size of data centers has
greatly increased. This, however, has resulted in significant increase in the
power consumption of the data centers. For this reason, managing power
consumption of data centers has become essential. In this paper, we highlight
the need of achieving energy efficiency in data centers and survey several
recent architectural techniques designed for power management of data centers.
We also present a classification of these techniques based on their
characteristics. This paper aims to provide insights into the techniques for
improving energy efficiency of data centers and encourage the designers to
invent novel solutions for managing the large power dissipation of data
centers.Comment: Keywords: Data Centers, Power Management, Low-power Design, Energy
Efficiency, Green Computing, DVFS, Server Consolidatio
An Algorithm for Network and Data-aware Placement of Multi-Tier Applications in Cloud Data Centers
Today's Cloud applications are dominated by composite applications comprising
multiple computing and data components with strong communication correlations
among them. Although Cloud providers are deploying large number of computing
and storage devices to address the ever increasing demand for computing and
storage resources, network resource demands are emerging as one of the key
areas of performance bottleneck. This paper addresses network-aware placement
of virtual components (computing and data) of multi-tier applications in data
centers and formally defines the placement as an optimization problem. The
simultaneous placement of Virtual Machines and data blocks aims at reducing the
network overhead of the data center network infrastructure. A greedy heuristic
is proposed for the on-demand application components placement that localizes
network traffic in the data center interconnect. Such optimization helps
reducing communication overhead in upper layer network switches that will
eventually reduce the overall traffic volume across the data center. This, in
turn, will help reducing packet transmission delay, increasing network
performance, and minimizing the energy consumption of network components.
Experimental results demonstrate performance superiority of the proposed
algorithm over other approaches where it outperforms the state-of-the-art
network-aware application placement algorithm across all performance metrics by
reducing the average network cost up to 67% and network usage at core switches
up to 84%, as well as increasing the average number of application deployments
up to 18%.Comment: Submitted for publication consideration for the Journal of Network
and Computer Applications (JNCA). Total page: 28. Number of figures: 15
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Insights into enzymatic halogenation from computational studies
The halogenases are a group of enzymes that have only come to the fore over the last 10 years thanks to the discovery and characterization of several novel representatives. They have revealed the fascinating variety of distinct chemical mechanisms that nature utilizes to activate halogens and introduce them into organic substrates. Computational studies using a range of approaches have already elucidated many details of the mechanisms of these enzymes, often in synergistic combination with experiment. This Review summarizes the main insights gained from these studies. It also seeks to identify open questions that are amenable to computational investigations. The studies discussed herein serve to illustrate some of the limitations of the current computational approaches and the challenges encountered in computational mechanistic enzymology
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