4,585 research outputs found
Phase Space Tomography of Matter-Wave Diffraction in the Talbot Regime
We report on the theoretical investigation of Wigner distribution function
(WDF) reconstruction of the motional quantum state of large molecules in de
Broglie interference. De Broglie interference of fullerenes and as the like
already proves the wavelike behaviour of these heavy particles, while we aim to
extract more quantitative information about the superposition quantum state in
motion. We simulate the reconstruction of the WDF numerically based on an
analytic probability distribution and investigate its properties by variation
of parameters, which are relevant for the experiment. Even though the WDF
described in the near-field experiment cannot be reconstructed completely, we
observe negativity even in the partially reconstructed WDF. We further consider
incoherent factors to simulate the experimental situation such as a finite
number of slits, collimation, and particle-slit van der Waals interaction. From
this we find experimental conditions to reconstruct the WDF from Talbot
interference fringes in molecule Talbot-Lau interferometry.Comment: 16 pages, 9 figures, accepted at New Journal of Physic
Microwave imaging techniques for biomedical applications
Microwaves have been considered for medical applications involving the detection of organ movements and changes in tissue water content. More particularly cardiopulmonary interrogation via microwaves has resulted in various sensors monitoring ventricular volume change or movement, arterial wall motion, respiratory movements, pulmonary oedema, etc. In all these applications, microwave sensors perform local measurements and need to be displaced for obtaining an image reproducing the spatial variations of a given quantity. Recently, advances in the area of inverse scattering theory and microwave technology have made possible the development of microwave imaging and tomographic instruments. This paper provides a review of such equipment developed at Suplec and UPC Barcelona, within the frame of successive French-Spanish PICASSO cooperation programs. It reports the most significant results and gives some perspectives for future developments. Firstly, a brief historical survey is given. Then, both technological and numerical aspects are considered. The results of preliminary pre-clinical assessments and in-lab experiments allow to illustrate the capabilities of the existing equipment, as well as its difficulty in dealing with clinical situations. Finally, some remarks on the expected development of microwave imaging techniques for biomedical applications are given.Peer ReviewedPostprint (published version
Histogram Tomography
In many tomographic imaging problems the data consist of integrals along
lines or curves. Increasingly we encounter "rich tomography" problems where the
quantity imaged is higher dimensional than a scalar per voxel, including
vectors tensors and functions. The data can also be higher dimensional and in
many cases consists of a one or two dimensional spectrum for each ray. In many
such cases the data contain not just integrals along rays but the distribution
of values along the ray. If this is discretized into bins we can think of this
as a histogram. In this paper we introduce the concept of "histogram
tomography". For scalar problems with histogram data this holds the possibility
of reconstruction with fewer rays. In vector and tensor problems it holds the
promise of reconstruction of images that are in the null space of related
integral transforms. For scalar histogram tomography problems we show how bins
in the histogram correspond to reconstructing level sets of function, while
moments of the distribution are the x-ray transform of powers of the unknown
function. In the vector case we give a reconstruction procedure for potential
components of the field. We demonstrate how the histogram longitudinal ray
transform data can be extracted from Bragg edge neutron spectral data and
hence, using moments, a non-linear system of partial differential equations
derived for the strain tensor. In x-ray diffraction tomography of strain the
transverse ray transform can be deduced from the diffraction pattern the full
histogram transverse ray transform cannot. We give an explicit example of
distributions of strain along a line that produce the same diffraction pattern,
and characterize the null space of the relevant transform.Comment: Small corrections from last versio
3D correlative single-cell imaging utilizing fluorescence and refractive index tomography
Cells alter the path of light, a fact that leads to well-known aberrations in
single cell or tissue imaging. Optical diffraction tomography (ODT) measures
the biophysical property that causes these aberrations, the refractive index
(RI). ODT is complementary to fluorescence imaging and does not require any
markers. The present study introduces RI and fluorescence tomography with
optofluidic rotation (RAFTOR) of suspended cells, quantifying the intracellular
RI distribution and colocalizing it with fluorescence in 3D. The technique is
validated with cell phantoms and used to confirm a lower nuclear RI for HL60
cells. Furthermore, the nuclear inversion of adult mouse photoreceptor cells is
observed in the RI distribution. The applications shown confirm predictions of
previous studies and illustrate the potential of RAFTOR to improve our
understanding of cells and tissues.Comment: 15 pages, 5 figure
Multi-scale characterisation of the 3D microstructure of a thermally-shocked bulk metallic glass matrix composite
Bulk metallic glass matrix composites (BMGMCs) are a new class of metal alloys which have significantly increased ductility and impact toughness, resulting from the ductile crystalline phases distributed uniformly within the amorphous matrix. However, the 3D structures and their morphologies of such composite at nano and micrometre scale have never been reported before. We have used high density electric currents to thermally shock a Zr-Ti based BMGMC to different temperatures, and used X-ray microtomography, FIB-SEM nanotomography and neutron diffraction to reveal the morphologies, compositions, volume fractions and thermal stabilities of the nano and microstructures. Understanding of these is essential for optimizing the design of BMGMCs and developing viable manufacturing methods
Two-Dimensional Magnetic Resonance Tomographic Microscopy using Ferromagnetic Probes
We introduce the concept of computerized tomographic microscopy in magnetic
resonance imaging using the magnetic fields and field gradients from a
ferromagnetic probe. We investigate a configuration where a two-dimensional
sample is under the influence of a large static polarizing field, a small
perpendicular radio-frequency field, and a magnetic field from a ferromagnetic
sphere. We demonstrate that, despite the non-uniform and non-linear nature of
the fields from a microscopic magnetic sphere, the concepts of computerized
tomography can be applied to obtain proper image reconstruction from the
original spectral data by sequentially varying the relative sample-sphere
angular orientation. The analysis shows that the recent proposal for atomic
resolution magnetic resonance imaging of discrete periodic crystal lattice
planes using ferromagnetic probes can also be extended to two-dimensional
imaging of non-crystalline samples with resolution ranging from micrometer to
Angstrom scales.Comment: 9 pages, 11 figure
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