Sparse MRI and CT Reconstruction

Sparse signal reconstruction is of the utmost importance for efficient medical imaging, conducting accurate screening for security and inspection, and for non-destructive testing. The sparsity of the signal is dictated by either feasibility, or the cost and the screening time constraints of the system. In this work, two major sparse signal reconstruction systems such as compressed sensing magnetic resonance imaging (MRI) and sparse-view computed tomography (CT) are investigated. For medical CT, a limited number of views (sparse-view) is an option for whether reducing the amount of ionizing radiation or the screening time and the cost of the procedure. In applications such as non-destructive testing or inspection of large objects, like a cargo container, one angular view can take up to a few minutes for only one slice. On the other hand, some views can be unavailable due to the configuration of the system. A problem of data sufficiency and on how to estimate a tomographic image when the projection data are not ideally sufficient for precise reconstruction is one of two major objectives of this work. Three CT reconstruction methods are proposed: algebraic iterative reconstruction-reprojection (AIRR), sparse-view CT reconstruction based on curvelet and total variation regularization (CTV), and sparse-view CT reconstruction based on nonconvex L1-L2 regularization. The experimental results confirm a high performance based on subjective and objective quality metrics. Additionally, sparse-view neutron-photon tomography is studied based on Monte-Carlo modelling to demonstrate shape reconstruction, material discrimination and visualization based on the proposed 3D object reconstruction method and material discrimination signatures. One of the methods for efficient acquisition of multidimensional signals is the compressed sensing (CS). A significantly low number of measurements can be obtained in different ways, and one is undersampling, that is sampling below the Shannon-Nyquist limit. Magnetic resonance imaging (MRI) suffers inherently from its slow data acquisition. The compressed sensing MRI (CSMRI) offers significant scan time reduction with advantages for patients and health care economics. In this work, three frameworks are proposed and evaluated, i.e., CSMRI based on curvelet transform and total generalized variation (CT-TGV), CSMRI using curvelet sparsity and nonlocal total variation: CS-NLTV, CSMRI that explores shearlet sparsity and nonlocal total variation: SS-NLTV. The proposed methods are evaluated experimentally and compared to the previously reported state-of-the-art methods. Results demonstrate a significant improvement of image reconstruction quality on different medical MRI datasets

A Theoretically Guaranteed Deep Optimization Framework for Robust Compressive Sensing MRI

Magnetic Resonance Imaging (MRI) is one of the most dynamic and safe imaging techniques available for clinical applications. However, the rather slow speed of MRI acquisitions limits the patient throughput and potential indi cations. Compressive Sensing (CS) has proven to be an efficient technique for accelerating MRI acquisition. The most widely used CS-MRI model, founded on the premise of reconstructing an image from an incompletely filled k-space, leads to an ill-posed inverse problem. In the past years, lots of efforts have been made to efficiently optimize the CS-MRI model. Inspired by deep learning techniques, some preliminary works have tried to incorporate deep architectures into CS-MRI process. Unfortunately, the convergence issues (due to the experience-based networks) and the robustness (i.e., lack real-world noise modeling) of these deeply trained optimization methods are still missing. In this work, we develop a new paradigm to integrate designed numerical solvers and the data-driven architectures for CS-MRI. By introducing an optimal condition checking mechanism, we can successfully prove the convergence of our established deep CS-MRI optimization scheme. Furthermore, we explicitly formulate the Rician noise distributions within our framework and obtain an extended CS-MRI network to handle the real-world nosies in the MRI process. Extensive experimental results verify that the proposed paradigm outperforms the existing state-of-the-art techniques both in reconstruction accuracy and efficiency as well as robustness to noises in real scene