Optical Diagnostics in Human Diseases

Optical technologies provide unique opportunities for the diagnosis of various pathological disorders. The range of biophotonics applications in clinical practice is considerably wide given that the optical properties of biological tissues are subject to significant changes during disease progression. Due to the small size of studied objects (from μm to mm) and despite some minimum restrictions (low-intensity light is used), these technologies have great diagnostic potential both as an additional tool and in cases of separate use, for example, to assess conditions affecting microcirculatory bed and tissue viability. This Special Issue presents topical articles by researchers engaged in the development of new methods and devices for optical non-invasive diagnostics in various fields of medicine. Several studies in this Special Issue demonstrate new information relevant to surgical procedures, especially in oncology and gynecology. Two articles are dedicated to the topical problem of breast cancer early detection, including during surgery. One of the articles is devoted to urology, namely to the problem of chronic or recurrent episodic urethral pain. Several works describe the studies in otolaryngology and dentistry. One of the studies is devoted to diagnosing liver diseases. A number of articles contribute to the studying of the alterations caused by diabetes mellitus and cardiovascular diseases. The results of all the presented articles reflect novel innovative research and emerging ideas in optical non-invasive diagnostics aimed at their wider translation into clinical practice

Sweat gland carcinoma of the breast: a morpho-histological study

VOLUME 1: 1. Sweat Gland Carcinoma of the Breast, 1932, EDINBURGH MEDICAL JOURNAL, VOL. XXXIX., No. 7, 1932. || 2. The Menopausal Age and Mammary Carcinoma, 1932, The Lancet. EDINBURGH MEDICAL JOURNAL, Vol. XL., 1932 || 3. Carcinoma in the Mammary Lobule and its Origin, 1933, EDINBURGH MEDICAL JOURNAL, Vol. XL., No. 2, 1933. || 4. Prognosis in Mammary Carcinoma in Relation to Grading and Treatment, pp. 61 - 80, (with M.C. Tod, pp. 81 - 95). 1934, EDINBURGH MEDICAL JOURNAL, NEW SERIES (IVth), VOL. XLI. || 5. The Diagnosis and Treatment of Doubtful Mammary Tumours, (with M.C. Tod), 1934, The Lancet. || 6. A Histological Study of the Normal Mamma in Relation to Tumour Growth, Part I. Early Development to Maturity, 1934, Edin. Med. Journ. || 7. A HISTOLOGICAL STUDY OF THE NORMAL MAMMA IN RELATION TO TUMOUR GROWTH. Part II, The Mature Gland in Pregnancy and Lactation, 1935, EDINBURGH MEDICAL JOURNAL, NEW SERIES (IVth), VOL. XLII., No. 12, 1935 . || 8. Record of a Case of Carcinoma of the Breast, With Survival for 24 years, with Local Recurrences and Metastases in Opposite Breast and Axilla (with M. C. Todd), 1936, SURGERY, GYNECOLOGY AND OBSTETRICS, January, 1936, Vol, 62, 90 -92.VOLUME 2: THE FREQUENCY AID VARIATION OF MALIGNANT CELL AND TISSUE CHARACTERS AND THE FREQUENCY AND EXTENT OF INVASIVE GROWTH IN MAMMARY CARCINOMA: A Survey of findings in 460 Breast Cancers