7 research outputs found
Coding-theorem Like Behaviour and Emergence of the Universal Distribution from Resource-bounded Algorithmic Probability
Previously referred to as `miraculous' in the scientific literature because
of its powerful properties and its wide application as optimal solution to the
problem of induction/inference, (approximations to) Algorithmic Probability
(AP) and the associated Universal Distribution are (or should be) of the
greatest importance in science. Here we investigate the emergence, the rates of
emergence and convergence, and the Coding-theorem like behaviour of AP in
Turing-subuniversal models of computation. We investigate empirical
distributions of computing models in the Chomsky hierarchy. We introduce
measures of algorithmic probability and algorithmic complexity based upon
resource-bounded computation, in contrast to previously thoroughly investigated
distributions produced from the output distribution of Turing machines. This
approach allows for numerical approximations to algorithmic
(Kolmogorov-Chaitin) complexity-based estimations at each of the levels of a
computational hierarchy. We demonstrate that all these estimations are
correlated in rank and that they converge both in rank and values as a function
of computational power, despite fundamental differences between computational
models. In the context of natural processes that operate below the Turing
universal level because of finite resources and physical degradation, the
investigation of natural biases stemming from algorithmic rules may shed light
on the distribution of outcomes. We show that up to 60\% of the
simplicity/complexity bias in distributions produced even by the weakest of the
computational models can be accounted for by Algorithmic Probability in its
approximation to the Universal Distribution.Comment: 27 pages main text, 39 pages including supplement. Online complexity
calculator: http://complexitycalculator.com
Training-free Measures Based on Algorithmic Probability Identify High Nucleosome Occupancy in DNA Sequences
We introduce and study a set of training-free methods of
information-theoretic and algorithmic complexity nature applied to DNA
sequences to identify their potential capabilities to determine nucleosomal
binding sites. We test our measures on well-studied genomic sequences of
different sizes drawn from different sources. The measures reveal the known in
vivo versus in vitro predictive discrepancies and uncover their potential to
pinpoint (high) nucleosome occupancy. We explore different possible signals
within and beyond the nucleosome length and find that complexity indices are
informative of nucleosome occupancy. We compare against the gold standard
(Kaplan model) and find similar and complementary results with the main
difference that our sequence complexity approach. For example, for high
occupancy, complexity-based scores outperform the Kaplan model for predicting
binding representing a significant advancement in predicting the highest
nucleosome occupancy following a training-free approach.Comment: 8 pages main text (4 figures), 12 total with Supplementary (1 figure