109,699 research outputs found
Object Discovery via Cohesion Measurement
Color and intensity are two important components in an image. Usually, groups
of image pixels, which are similar in color or intensity, are an informative
representation for an object. They are therefore particularly suitable for
computer vision tasks, such as saliency detection and object proposal
generation. However, image pixels, which share a similar real-world color, may
be quite different since colors are often distorted by intensity. In this
paper, we reinvestigate the affinity matrices originally used in image
segmentation methods based on spectral clustering. A new affinity matrix, which
is robust to color distortions, is formulated for object discovery. Moreover, a
Cohesion Measurement (CM) for object regions is also derived based on the
formulated affinity matrix. Based on the new Cohesion Measurement, a novel
object discovery method is proposed to discover objects latent in an image by
utilizing the eigenvectors of the affinity matrix. Then we apply the proposed
method to both saliency detection and object proposal generation. Experimental
results on several evaluation benchmarks demonstrate that the proposed CM based
method has achieved promising performance for these two tasks.Comment: 14 pages, 14 figure
Context-aware visual exploration of molecular databases
Facilitating the visual exploration of scientific data has
received increasing attention in the past decade or so. Especially
in life science related application areas the amount
of available data has grown at a breath taking pace. In this
paper we describe an approach that allows for visual inspection
of large collections of molecular compounds. In
contrast to classical visualizations of such spaces we incorporate
a specific focus of analysis, for example the outcome
of a biological experiment such as high throughout
screening results. The presented method uses this experimental
data to select molecular fragments of the underlying
molecules that have interesting properties and uses the
resulting space to generate a two dimensional map based
on a singular value decomposition algorithm and a self organizing
map. Experiments on real datasets show that
the resulting visual landscape groups molecules of similar
chemical properties in densely connected regions
Expression cartography of human tissues using self organizing maps
Background: The availability of parallel, high-throughput microarray and sequencing experiments poses a challenge how to best arrange and to analyze the obtained heap of multidimensional data in a concerted way. Self organizing maps (SOM), a machine learning method, enables the parallel sample- and gene-centered view on the data combined with strong visualization and second-level analysis capabilities. The paper addresses aspects of the method with practical impact in the context of expression analysis of complex data sets.
Results: The method was applied to generate a SOM characterizing the whole genome expression profiles of 67 healthy human tissues selected from ten tissue categories (adipose, endocrine, homeostasis, digestion, exocrine, epithelium, sexual reproduction, muscle, immune system and nervous tissues). SOM mapping reduces the dimension of expression data from ten thousands of genes to a few thousands of metagenes where each metagene acts as representative of a minicluster of co-regulated single genes. Tissue-specific and common properties shared between groups of tissues emerge as a handful of localized spots in the tissue maps collecting groups of co-regulated and co-expressed metagenes. The functional context of the spots was discovered using overrepresentation analysis with respect to pre-defined gene sets of known functional impact. We found that tissue related spots typically contain enriched populations of gene sets well corresponding to molecular processes in the respective tissues. Analysis techniques normally used at the gene-level such as two-way hierarchical clustering provide a better signal-to-noise ratio and a better representativeness of the method if applied to the metagenes. Metagene-based clustering analyses aggregate the tissues into essentially three clusters containing nervous, immune system and the remaining tissues. 
Conclusions: The global view on the behavior of a few well-defined modules of correlated and differentially expressed genes is more intuitive and more informative than the separate discovery of the expression levels of hundreds or thousands of individual genes. The metagene approach is less sensitive to a priori selection of genes. It can detect a coordinated expression pattern whose components would not pass single-gene significance thresholds and it is able to extract context-dependent patterns of gene expression in complex data sets.

Why do These Match? Explaining the Behavior of Image Similarity Models
Explaining a deep learning model can help users understand its behavior and
allow researchers to discern its shortcomings. Recent work has primarily
focused on explaining models for tasks like image classification or visual
question answering. In this paper, we introduce Salient Attributes for Network
Explanation (SANE) to explain image similarity models, where a model's output
is a score measuring the similarity of two inputs rather than a classification
score. In this task, an explanation depends on both of the input images, so
standard methods do not apply. Our SANE explanations pairs a saliency map
identifying important image regions with an attribute that best explains the
match. We find that our explanations provide additional information not
typically captured by saliency maps alone, and can also improve performance on
the classic task of attribute recognition. Our approach's ability to generalize
is demonstrated on two datasets from diverse domains, Polyvore Outfits and
Animals with Attributes 2. Code available at:
https://github.com/VisionLearningGroup/SANEComment: Accepted at ECCV 202
An Overview of the Use of Neural Networks for Data Mining Tasks
In the recent years the area of data mining has experienced a considerable demand for technologies that extract knowledge from large and complex data sources. There is a substantial commercial interest as well as research investigations in the area that aim to develop new and improved approaches for extracting information, relationships, and patterns from datasets. Artificial Neural Networks (NN) are popular biologically inspired intelligent methodologies, whose classification, prediction and pattern recognition capabilities have been utilised successfully in many areas, including science, engineering, medicine, business, banking, telecommunication, and many other fields. This paper highlights from a data mining perspective the implementation of NN, using supervised and unsupervised learning, for pattern recognition, classification, prediction and cluster analysis, and focuses the discussion on their usage in bioinformatics and financial data analysis tasks
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