Cluster Analysis of Finger-to-nose Test for Spinocerebellar Ataxia Assessment

El test Finger-to-nose test (FNT) es una evaluación neurológica para estudiar la coordinación. Se presenta una metodología de análisis de datos de FNT, que permite evaluar la evolución del estado de enfermos de Ataxia Espinocerebral de tipo 2 (SCA2), mediante técnicas de aprendizaje computacional.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Aplicaciones de la transformada wavelet en el procesamiento de biopotenciales electrooculográficos

Conferencia impartida por el Pr. Dr. Rodolfo García Bermúdez en la ETSI Telecomunicación y ETSI Informática dentro del programa de conferencias científicas incluido en el Plan Propio.Organiza el Departamento de Tecnología ElectrónicaA partir de una panorámica general acerca de los biopotenciales electro-oculográficos, con énfasis en movimientos oculares sacádicos, se describirán algunos de los retos presentes en su procesamiento: la simulación de estas señales por medio de funciones, algunas técnicas para la eliminación de ruido y la obtención de perfiles de velocidad por medio de diferenciación aplicando transformada wavelet.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Distinguishing Patients With a Coordination Disorder From Healthy Controls Using Local Features of Movement Trajectories During the Finger-to-Nose Test

Assessment of coordination disorders is valuable for monitoring progression of patients, distinguishing healthy and pathological conditions, and ultimately aiding in clinical decision making, thereby offering the possibility to improve medical care or rehabilitation. A common method to assess movement disorders is by using clinical rating scales. However, rating scales depend on the evaluation and interpretation of an observer, implying that subjective phenotypic assignment precedes the application of the scales. Objective and more accurate methods are under continuous development but gold standards are still scarce. Here, we show how a method we previously developed, originally aimed at assessing dynamic balance by a probabilistic generalized linear model, can be used to assess a broader range of functional movements. In this paper, the method is applied to distinguish patients with coordination disorders from healthy controls. We focused on movements recorded during the finger-to-nose task (FNT), which is commonly used to assess coordination disorders. We also compared clinical FNT scores and model scores. Our method achieved 84% classification accuracy in distinguishing patients and healthy participants, using only two features. Future work could entail testing the reliability of the method by using additional features and other clinical tests such as finger chasing, quiet standing, and/or usage of tracking devices such as depth cameras or force plates