14,917 research outputs found
ConfidentCare: A Clinical Decision Support System for Personalized Breast Cancer Screening
Breast cancer screening policies attempt to achieve timely diagnosis by the
regular screening of apparently healthy women. Various clinical decisions are
needed to manage the screening process; those include: selecting the screening
tests for a woman to take, interpreting the test outcomes, and deciding whether
or not a woman should be referred to a diagnostic test. Such decisions are
currently guided by clinical practice guidelines (CPGs), which represent a
one-size-fits-all approach that are designed to work well on average for a
population, without guaranteeing that it will work well uniformly over that
population. Since the risks and benefits of screening are functions of each
patients features, personalized screening policies that are tailored to the
features of individuals are needed in order to ensure that the right tests are
recommended to the right woman. In order to address this issue, we present
ConfidentCare: a computer-aided clinical decision support system that learns a
personalized screening policy from the electronic health record (EHR) data.
ConfidentCare operates by recognizing clusters of similar patients, and
learning the best screening policy to adopt for each cluster. A cluster of
patients is a set of patients with similar features (e.g. age, breast density,
family history, etc.), and the screening policy is a set of guidelines on what
actions to recommend for a woman given her features and screening test scores.
ConfidentCare algorithm ensures that the policy adopted for every cluster of
patients satisfies a predefined accuracy requirement with a high level of
confidence. We show that our algorithm outperforms the current CPGs in terms of
cost-efficiency and false positive rates
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An intelligent system for risk classification of stock investment projects
The proposed paper demonstrates that a hybrid fuzzy neural network can serve as a risk classifier of stock investment projects. The training algorithm for the regular part of the network is based on bidirectional incremental evolution proving more efficient than direct evolution. The approach is compared with other crisp and soft investment appraisal and trading techniques, while building a multimodel domain representation for an intelligent decision support system. Thus the advantages of each model are utilised while looking at the investment problem from different perspectives. The empirical results are based on UK companies traded on the London Stock Exchange
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