Recent Advances on Modeling the Lateral Flow Immunoassay

The rapid immunochromatographic test strip, also called lateral flow immunoassay (LFIA), has recently attracted considerable research attention in the past decade because of its advantages when applied to a wide variety of point-of-care (POC) tests. This paper reviewed recent advances on modeling the LFIA and summarized their advantages and limitations. It is worth mentioning that there is a growing research interest on the general modeling issue for the LFIA system. In order to optimize LFIA performance for the purpose of quantification, it is of great importance to develop a mathematical model that allows us to simulate dynamic characteristics and also find out the effects of various design parameters in a both rapid and inexpensive way