Mathematical modelling of the cardiovascular system

In this paper we will address the problem of developing mathematical models for the numerical simulation of the human circulatory system. In particular, we will focus our attention on the problem of haemodynamics in large human arteries

G conditioning suit Patent

Conditioning suit for normal function of astronaut cardiovascular system in gravity environmen

Gravitational Force and the Cardiovascular System

Cardiovascular responses to changes in gravitational force are considered. Man is ideally suited to his 1-g environment. Although cardiovascular adjustments are required to accommodate to postural changes and exercise, these are fully accomplished for short periods (min). More challenging stresses are those of short-term microgravity (h) and long-term microgravity (days) and of gravitational forces greater than that of Earth. The latter can be simulated in the laboratory and quantitative studies can be conducted

The multifaceted roles of PI3Kγ in hypertension, vascular biology, and inflammation

PI3Kγ is a multifaceted protein, crucially involved in cardiovascular and immune systems. Several studies described the biological and physiological functions of this enzyme in the regulation of cardiovascular system, while others stressed its role in the modulation of immunity. Although PI3Kγ has been historically investigated for its role in leukocytes, the last decade of research also dedicated efforts to explore its functions in the cardiovascular system. In this review, we report an overview recapitulating how PI3Kγ signaling participates in the regulation of vascular functions involved in blood pressure regulation. Moreover, we also summarize the main functions of PI3Kγ in immune responses that could be potentially important in the interaction with the cardiovascular system. Considering that vascular and immune mechanisms are increasingly emerging as intertwining players in hypertension, PI3Kγ could be an intriguing pathway acting on both sides. The availability of specific inhibitors introduces a perspective of further translational research and clinical approaches that could be exploited in hypertension

Evaluation of the cardiovascular system during various circulatory stresses Progress report, 1 Jun. 1969 - 30 May 1970

Cardiovascular system evaluation during various circulatory stresse

Cardiovascular System Studies

Contains reports on two research projects.National Institutes of Health (Grant 5T1 HE 5550-02

Cardiovascular System Studies

Contains research objectives and reports on one research project.National Institutes of Health (Grant 5 TI HE 5550-03

Studies of the effects of acceleration on cardiovascular and respiratory dynamics Semiannual status report, 1 Oct. 1965 - 1 Apr. 1966

Acceleration stress effects on animal respiratory and cardiovascular system

Electronic circuit detects left ventricular ejection events in cardiovascular system

Electronic circuit processes arterial blood pressure waveform to produce discrete signals that coincide with beginning and end of left ventricular ejection. Output signals provide timing signals for computers that monitor cardiovascular systems. Circuit operates reliably for heart rates between 50 and 200 beats per minute