Combined effect of neolamarckia cadamba leaves and electroporation method on hela cell anti- proliferation process

This study suggests that natural sources may become an important tool in treating cancer. Neolamarckia cadamba (NC) leaves also well-known as “Anthocephalus Cadamba”, is a precious plant in Ayurvedic medicine. HeLa cells are one of the examples of eukaryotic cells type. It is derived from human cervical cancer cells. This experiment is conducted in different concentrations of NC Leaves (1μg/ml, 5μg/ml, 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml, 50μg/ml, 60μg/ml, 70μg/ml, 80μg/ml, 90μg/ml and 100μg/ml) for 48 hours. This experiment’s result proves that the anti-cancer properties of the extract of NC leaves are by increasing the concentration of extract, the numbers of cell viability will decrease. For contribution, the process of NC leaves extract will be combined with the electroporation process to investigate the effect on HeLa cell. Electroporation parameters used for this study were (voltage 600v/cm, pulse duration 5ms, single pulse)

Annona muricata (graviola): toxic or therapeutic

This paper examines annona muricata (graviola): toxic or therapeutic

Cassane diterpenoids from lonchocarpus laxiflorus

This article examines cassane diterpenoids from lonchocarpus laxiflorus

IIT teams use plant extract, heat to kill skin cancer cells

“Uptake of the nanoformulation is nearly the same by normal and cancerous cells. But the extract produces elevated levels of ROS only in cancerous cells. Right now we don’t know the precise mechanism by which higher ROS is generated inside cancer cells,” says Dr. Aravind Kumar Rengan from the Department of Biomedical Engineering at IIT Hyderabad and one of the corresponding authors of the paper. The levels of ROS inside normal cells were insignificant

Formulation and Evaluation of Polyherbal Anthelmintic Preparation

The present study was done with the aim to formulate an anthelmintic preparation and to evaluate anthelmintic activity of formulation containing traditionally user herbs viz., Plumbago zeylanica (leaves), Hyoscyamus niger (roots) and Abultion indicum (leaves) using adult earthworm Pheritima posthuma. The aqueous and ethanolic extract of the crude drug of different concentration were tested which involve determination of paralysis time and time to kill the worms. Piperazine citrate was used as standard and it was found that the PHFEE activity is higher than PHFAE

Variation and Relationship of Selected Wood Properties in Planted Kelempayan (Neolamarckia Cadamba (Roxb.) Bosser)

The tall and straight bole of Kelempayan (Neolamarckia cadamba (Roxb.) Bosser), a fast-growing indigenous species, has the potential to be used for forest plantation species. This study was carried out to evaluate the inherent properties of the wood. Six planted trees under similar site conditions were sampled along their radii and at five different height levels to evaluate the inherent variation of wood and the influence of anatomical properties on its specific gravity (SG) and bending strength. Over all me ans for SG was 0.36, green moisture content 174.83 percent (%), tangential shrinkage 6.46%, radial shrinkage 3.28% and volumetric shrinkage 9.90%. The overall means for modulus of elasticity ( MOE) and modulus of rupture {MOR ) were 7667 and 71 megapascal (MPa) respectively. Vessel comprised 16.69% of wood, ray 11.96% and fibre 71.41%. Fibre length averaged 1.38 millimeter, fibre diameter 35.01 microns, fibre lumen diameter 24.82 microns and fibre wall thickness 5.11 microns. These physical and mechanical properties are similar to many other light hardwoods species, indicating the suitability of wood for general utility timber

Corrosion inhibition of mild steel in 15 wt.% HCl by durum wheat

The toxicity of most commercial corrosion inhibitors and strict environmental legislations have required the development of environmentally-friendly, cheap and non-toxic inhibitors. The use of natural products, especially of plant origin as corrosion inhibitors has become an area of increasing research because plant extracts contain an incredibly rich source of natural chemical compounds which can be extracted by simple procedures at low-cost. Durum wheat was investigated in this work because functional groups were identified which suggested that it could be a promising potential inhibitor. The corrosion of mild steel in 15 wt.% HCl solution with and without Durum wheat was investigated and directly compared to results from two commercial corrosion inhibitors, propargyl alcohol and 2- mercaptobenzimidazole, under the same conditions, by comparing weight loss with and without inhibition. The durum wheat powder and adsorbed films were characterised by Fourier transform infrared spectroscopy (FTIR), and the exposed samples were characterised using SEM, EDS spectroscopy and surface profilometry. The effects of concentration, temperature (20-60°C) and immersion time (5-24 h) on the corrosion inhibition were investigated. Durum wheat was shown to be a successful green corrosion inhibitor with a room temperature inhibition efficiency of 97% (as compared to values of 99% and 97% for propargyl alcohol and 2 - mercapto benzimidazole respectively) and at a lower cost per l L of corrosive solution. However, at the severe corrosive conditions chosen for this research, the inhibition performance of both durum wheat and 2- mercaptobenzimidazole was influenced by time and temperature, and the durum wheat corrosion inhibition was reduced to 78% after 24 hours at 60°C, compared to 88% for 2- mercaptobenzimidazole. All the inhibitors investigated obeyed Langmuir adsorption isotherm

Wound Healing Plants of Jalgaon District of Maharashtra State, India

Jalgaon District of Maharashtra state (India) has a great heritage and rich in various green and semi evergreen species. Record of 3347 species from 201 families appeared in earlier literature from Jalgaon District. A list of 283 wound healing plants of Indian origin is compiled; out of these 224 plants are native of Maharashtra, a 131 plants among them occurred in Jalgaon District, which are in practice by local herbalist, Vaidyas and nonregistered medical practitioners and Mukhiya (Head) of tribal community. Taxonomical distribution showed 93.63% dicot and 6.37% monocot and a single aquatic plant. The investigation revealed that wound healing natural products usually localized in root (27% ) \u3e leaves (20%) \u3e stem \u3e seed \u3e whole plant \u3e fruit \u3e flower \u3e rhizome \u3e tuber \u3e shoot \u3e stamen \u3e grain \u3e gall \u3e filament and plant product like latex (46%), oil (40%) , gum and resin (7%) as evident from this survey. Most of the remedies consisted of either single plant part or combination. Methods of preparation varies and they are species specific viz: plant parts applied as a paste, juice extracted from the fresh plant parts, powder made from fresh or dried plant parts, some fresh plant parts, and decoction. In this study the most dominant family was Leguminosae and roots were most frequently used for wound healing. Here an attempt has also been made to work out on plants belonging to Jalgaon District in order to exploit them for preparation of ointment that can be used both in human and domestic animals

Anthelmintic Activity of Root Bark of Balanites aegyptiaca (L.) Del.

The crude extracts of Balanites aegyptiaca (L.) Delile (Balanitaceae) was evaluated for anthelmintic activity using adult earthworms; the bark extract exhibited a dosedependent inhibition of spontaneous motility (paralysis). The result shows that the aqueous extract possesses wormicidal activity and thus, may be useful as an anthelmintic

Experimental and quantum chemical calculations on corrosion inhibition of mild steel by two furan derivatives

Two furan derivatives namely 5-methylfurfurylamine (MFA) and furfurylamine (FAM) were investigated as corrosion inhibitors for mild steel in 1 M HCl. The corrosion inhibition efficiencies (IE) were measured at 0.005M of the inhibitors using electrochemical potentiodynamic polarization measurements. The studied furan derivatives inhibit mild steel corrosion in acidic medium. The MFA shows higher inhibition efficiency of 84.77% compared to FAM of 41.75%. Quantum chemical calculations were performed at the B3LYP/6-311++G(d,p) level of density functional theory (DFT). Several quantum parameters were calculated to study the correlation between the molecular structures and the corrosion inhibition performance of the inhibitors. The MFA inhibitor shows higher HOMO energy, softness (S), fraction of electrons transferred (ΔN), and lower energy gap (ΔE) compared to the FAM. This result indicates a better corrosion inhibition performance of the MFA inhibitor. The results show that the calculated values of the quantum parameters using DFT calculations are consistent with the experimental findings