78,291 research outputs found
Decoding the Encoding of Functional Brain Networks: an fMRI Classification Comparison of Non-negative Matrix Factorization (NMF), Independent Component Analysis (ICA), and Sparse Coding Algorithms
Brain networks in fMRI are typically identified using spatial independent
component analysis (ICA), yet mathematical constraints such as sparse coding
and positivity both provide alternate biologically-plausible frameworks for
generating brain networks. Non-negative Matrix Factorization (NMF) would
suppress negative BOLD signal by enforcing positivity. Spatial sparse coding
algorithms ( Regularized Learning and K-SVD) would impose local
specialization and a discouragement of multitasking, where the total observed
activity in a single voxel originates from a restricted number of possible
brain networks.
The assumptions of independence, positivity, and sparsity to encode
task-related brain networks are compared; the resulting brain networks for
different constraints are used as basis functions to encode the observed
functional activity at a given time point. These encodings are decoded using
machine learning to compare both the algorithms and their assumptions, using
the time series weights to predict whether a subject is viewing a video,
listening to an audio cue, or at rest, in 304 fMRI scans from 51 subjects.
For classifying cognitive activity, the sparse coding algorithm of
Regularized Learning consistently outperformed 4 variations of ICA across
different numbers of networks and noise levels (p0.001). The NMF algorithms,
which suppressed negative BOLD signal, had the poorest accuracy. Within each
algorithm, encodings using sparser spatial networks (containing more
zero-valued voxels) had higher classification accuracy (p0.001). The success
of sparse coding algorithms may suggest that algorithms which enforce sparse
coding, discourage multitasking, and promote local specialization may capture
better the underlying source processes than those which allow inexhaustible
local processes such as ICA
Separating a Real-Life Nonlinear Image Mixture
When acquiring an image of a paper document, the image printed on the back page sometimes shows through. The mixture of the front- and back-page images thus obtained is markedly nonlinear, and thus constitutes a good real-life test case for nonlinear blind source separation.
This paper addresses a difficult version of this problem, corresponding to the use of "onion skin" paper, which results in a relatively strong nonlinearity of the mixture, which becomes close to singular in the lighter regions of the images. The separation is achieved through the MISEP technique, which is an extension of the well known INFOMAX method. The separation results are assessed with objective quality measures. They show an improvement over the results obtained with linear separation, but have room for further improvement
Information Theoretical Estimators Toolbox
We present ITE (information theoretical estimators) a free and open source,
multi-platform, Matlab/Octave toolbox that is capable of estimating many
different variants of entropy, mutual information, divergence, association
measures, cross quantities, and kernels on distributions. Thanks to its highly
modular design, ITE supports additionally (i) the combinations of the
estimation techniques, (ii) the easy construction and embedding of novel
information theoretical estimators, and (iii) their immediate application in
information theoretical optimization problems. ITE also includes a prototype
application in a central problem class of signal processing, independent
subspace analysis and its extensions.Comment: 5 pages; ITE toolbox: https://bitbucket.org/szzoli/ite
Techniques for noise removal from EEG, EOG and air flow signals in sleep patients
Noise is present in the wide variety of signals obtained from sleep patients.
This noise comes from a number of sources, from presence of extraneous signals
to adjustments in signal amplification and shot noise in the circuits used for
data collection. The noise needs to be removed in order to maximize the
information gained about the patient using both manual and automatic analysis
of the signals. Here we evaluate a number of new techniques for removal of that
noise, and the associated problem of separating the original signal sources.Comment: 9 pages, 3 figure
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