Tecnologias coerentes para redes ópticas flexíveis

Next-generation networks enable a broad range of innovative services with the best delivery by utilizing very dense wired/wireless networks. However, the development of future networks will require several breakthroughs in optical networks such as high-performance optical transceivers to support a very-high capacity optical network as well as optimization of the network concept, ensuring a dramatic reduction of the cost per bit. At the same time, all of the optical network segments (metro, access, long-haul) need new technology options to support high capacity, spectral efficiency and data-rate flexibility. Coherent detection offers an opportunity by providing very high sensitivity and supporting high spectral efficiency. Coherent technology can still be combined with polarization multiplexing. Despite the increased cost and complexity, the migration to dual-polarization coherent transceivers must be considered, as it enables to double the spectral efficiency. These dual-polarization systems require an additional digital signal processing (DSP) subsystem for polarization demultiplexing. This work seeks to provide and characterize cost-effective novel coherent transceivers for the development of new generation practical, flexible and high capacity transceivers for optical metro-access and data center interconnects. In this regard, different polarization demultiplexing (PolDemux) algorithms, as well as adaptive Stokes will be considered. Furthermore, low complexity and modulation format-agnostic DSP techniques based on adaptive Stokes PolDemux for flexible and customizable optical coherent systems will be proposed. On this subject, the performance of the adaptive Stokes algorithm in an ultra-dense wavelength division multiplexing (U-DWDM) system will be experimentally evaluated, in offline and real-time operations over a hybrid optical-wireless link. In addition, the efficiency of this PolDemux algorithm in a flexible optical metro link based on Nyquist pulse shaping U-DWDM system and hybrid optical signals will be assessed. Moreover, it is of great importance to find a transmission technology that enables to apply the Stokes PolDemux for long-haul transmission systems and data center interconnects. In this work, it is also proposed a solution based on the use of digital multi-subcarrier multiplexing, which improve the performance of long-haul optical systems, without increasing substantially, their complexity and cost.As redes de telecomunicações futuras permitirão uma ampla gama de serviços inovadores e com melhor desempenho. No entanto, o desenvolvimento das futuras redes implicará vários avanços nas redes de fibra ótica, como transcetores óticos de alto desempenho capazes de suportar ligações de muito elevada capacidade, e a otimização da estrutura da rede, permitindo uma redução drástica do custo por bit transportado. Simultaneamente, todos os segmentos de rede ótica (metropolitanas, acesso e longo alcance) necessitam de novas opções tecnológicas para suportar uma maior capacidade, maior eficiência espetral e flexibilidade. Neste contexto, a deteção coerente surge como uma oportunidade, fornecendo alta sensibilidade e elevada eficiência espetral. A tecnologia de deteção coerente pode ainda ser associada à multiplexação na polarização. Apesar de um potencial aumento ao nível do custo e da complexidade, a migração para transcetores coerentes de dupla polarização deve ser ponderada, pois permite duplicar a eficiência espetral. Esses sistemas de dupla polarização requerem um subsistema de processamento digital de sinal (DSP) adicional para desmultiplexagem da polarização. Este trabalho procura fornecer e caracterizar novos transcetores coerentes de baixo custo para o desenvolvimento de uma nova geração de transcetores mais práticos, flexíveis e de elevada capacidade, para interconexões óticas ao nível das futuras redes de acesso e metro. Assim, serão analisados diferentes algoritmos para a desmultiplexagem da polarização, incluindo uma abordagem adaptativa baseada no espaço de Stokes. Além disso, são propostas técnicas de DSP independentes do formato de modulação e de baixa complexidade baseadas na desmultiplexagem de Stokes adaptativa para sistemas óticos coerentes flexíveis. Neste contexto, o desempenho do algoritmo adaptativo de desmultiplexagem na polarização baseado no espaço de Stokes é avaliado experimentalmente num sistema U-DWDM, tanto em análises off-line como em tempo real, considerando um percurso ótico hibrido que combina um sistema de transmissão suportado por fibra e outro em espaço livre. Foi ainda analisada a eficiência do algoritmo de desmultiplexagem na polarização numa rede ótica de acesso flexível U-DWDM com formatação de pulso do tipo Nyquist. Neste trabalho foi ainda analisada a aplicação da técnica de desmultiplexagem na polarização baseada no espaço de Stokes para sistemas de longo alcance. Assim, foi proposta uma solução de aplicação baseada no uso da multiplexagem digital de múltiplas sub-portadoras, tendo-se demonstrado uma melhoria na eficiência do desempenho dos sistemas óticos de longo alcance, sem aumentar significativamente a respetiva complexidade e custo.Programa Doutoral em Engenharia Eletrotécnic

Design of Multi-Gigabit Network Interconnect Elements and Protocols for a Data Acquisition System in Radiation Environments

Modern High Energy Physics experiments (HEP) explore the fundamental nature of matter in more depth than ever before and thereby benefit greatly from the advances in the field of communication technology. The huge data volumes generated by the increasingly precise detector setups pose severe problems for the Data Acquisition Systems (DAQ), which are used to process and store this information. In addition, detector setups and their read-out electronics need to be synchronized precisely to allow a later correlation of experiment events accurately in time. Moreover, the substantial presence of charged particles from accelerator-generated beams results in strong ionizing radiation levels, which has a severe impact on the electronic systems. This thesis recommends an architecture for unified network protocol IP cores with custom developed physical interfaces for the use of reliable data acquisition systems in strong radiation environments. Special configured serial bidirectional point-to-point interconnects are proposed to realize high speed data transmission, slow control access, synchronization and global clock distribution on unified links to reduce costs and to gain compact and efficient read-out setups. Special features are the developed radiation hardened functional units against single and multiple bit upsets, and the common interface for statistical error and diagnosis information, which integrates well into the protocol capabilities and eases the error handling in large experiment setups. Many innovative designs for several custom FPGA and ASIC platforms have been implemented and are described in detail. Special focus is placed on the physical layers and network interface elements from high-speed serial LVDS interconnects up to 20 Gb/s SSTL links in state-of-the-art process technology. The developed IP cores are fully tested by an adapted verification environment for electronic design automation tools and also by live application. They are available in a global repository allowing a broad usage within further HEP experiments

Mobile and Wireless Communications

Mobile and Wireless Communications have been one of the major revolutions of the late twentieth century. We are witnessing a very fast growth in these technologies where mobile and wireless communications have become so ubiquitous in our society and indispensable for our daily lives. The relentless demand for higher data rates with better quality of services to comply with state-of-the art applications has revolutionized the wireless communication field and led to the emergence of new technologies such as Bluetooth, WiFi, Wimax, Ultra wideband, OFDMA. Moreover, the market tendency confirms that this revolution is not ready to stop in the foreseen future. Mobile and wireless communications applications cover diverse areas including entertainment, industrialist, biomedical, medicine, safety and security, and others, which definitely are improving our daily life. Wireless communication network is a multidisciplinary field addressing different aspects raging from theoretical analysis, system architecture design, and hardware and software implementations. While different new applications are requiring higher data rates and better quality of service and prolonging the mobile battery life, new development and advanced research studies and systems and circuits designs are necessary to keep pace with the market requirements. This book covers the most advanced research and development topics in mobile and wireless communication networks. It is divided into two parts with a total of thirty-four stand-alone chapters covering various areas of wireless communications of special topics including: physical layer and network layer, access methods and scheduling, techniques and technologies, antenna and amplifier design, integrated circuit design, applications and systems. These chapters present advanced novel and cutting-edge results and development related to wireless communication offering the readers the opportunity to enrich their knowledge in specific topics as well as to explore the whole field of rapidly emerging mobile and wireless networks. We hope that this book will be useful for students, researchers and practitioners in their research studies

Dirty RF Signal Processing for Mitigation of Receiver Front-end Non-linearity

Moderne drahtlose Kommunikationssysteme stellen hohe und teilweise gegensätzliche Anforderungen an die Hardware der Funkmodule, wie z.B. niedriger Energieverbrauch, große Bandbreite und hohe Linearität. Die Gewährleistung einer ausreichenden Linearität ist, neben anderen analogen Parametern, eine Herausforderung im praktischen Design der Funkmodule. Der Fokus der Dissertation liegt auf breitbandigen HF-Frontends für Software-konfigurierbare Funkmodule, die seit einigen Jahren kommerziell verfügbar sind. Die praktischen Herausforderungen und Grenzen solcher flexiblen Funkmodule offenbaren sich vor allem im realen Experiment. Eines der Hauptprobleme ist die Sicherstellung einer ausreichenden analogen Performanz über einen weiten Frequenzbereich. Aus einer Vielzahl an analogen Störeffekten behandelt die Arbeit die Analyse und Minderung von Nichtlinearitäten in Empfängern mit direkt-umsetzender Architektur. Im Vordergrund stehen dabei Signalverarbeitungsstrategien zur Minderung nichtlinear verursachter Interferenz - ein Algorithmus, der besser unter "Dirty RF"-Techniken bekannt ist. Ein digitales Verfahren nach der Vorwärtskopplung wird durch intensive Simulationen, Messungen und Implementierung in realer Hardware verifiziert. Um die Lücken zwischen Theorie und praktischer Anwendbarkeit zu schließen und das Verfahren in reale Funkmodule zu integrieren, werden verschiedene Untersuchungen durchgeführt. Hierzu wird ein erweitertes Verhaltensmodell entwickelt, das die Struktur direkt-umsetzender Empfänger am besten nachbildet und damit alle Verzerrungen im HF- und Basisband erfasst. Darüber hinaus wird die Leistungsfähigkeit des Algorithmus unter realen Funkkanal-Bedingungen untersucht. Zusätzlich folgt die Vorstellung einer ressourceneffizienten Echtzeit-Implementierung des Verfahrens auf einem FPGA. Abschließend diskutiert die Arbeit verschiedene Anwendungsfelder, darunter spektrales Sensing, robuster GSM-Empfang und GSM-basiertes Passivradar. Es wird gezeigt, dass nichtlineare Verzerrungen erfolgreich in der digitalen Domäne gemindert werden können, wodurch die Bitfehlerrate gestörter modulierter Signale sinkt und der Anteil nichtlinear verursachter Interferenz minimiert wird. Schließlich kann durch das Verfahren die effektive Linearität des HF-Frontends stark erhöht werden. Damit wird der zuverlässige Betrieb eines einfachen Funkmoduls unter dem Einfluss der Empfängernichtlinearität möglich. Aufgrund des flexiblen Designs ist der Algorithmus für breitbandige Empfänger universal einsetzbar und ist nicht auf Software-konfigurierbare Funkmodule beschränkt.Today's wireless communication systems place high requirements on the radio's hardware that are largely mutually exclusive, such as low power consumption, wide bandwidth, and high linearity. Achieving a sufficient linearity, among other analogue characteristics, is a challenging issue in practical transceiver design. The focus of this thesis is on wideband receiver RF front-ends for software defined radio technology, which became commercially available in the recent years. Practical challenges and limitations are being revealed in real-world experiments with these radios. One of the main problems is to ensure a sufficient RF performance of the front-end over a wide bandwidth. The thesis covers the analysis and mitigation of receiver non-linearity of typical direct-conversion receiver architectures, among other RF impairments. The main focus is on DSP-based algorithms for mitigating non-linearly induced interference, an approach also known as "Dirty RF" signal processing techniques. The conceived digital feedforward mitigation algorithm is verified through extensive simulations, RF measurements, and implementation in real hardware. Various studies are carried out that bridge the gap between theory and practical applicability of this approach, especially with the aim of integrating that technique into real devices. To this end, an advanced baseband behavioural model is developed that matches to direct-conversion receiver architectures as close as possible, and thus considers all generated distortions at RF and baseband. In addition, the algorithm's performance is verified under challenging fading conditions. Moreover, the thesis presents a resource-efficient real-time implementation of the proposed solution on an FPGA. Finally, different use cases are covered in the thesis that includes spectrum monitoring or sensing, GSM downlink reception, and GSM-based passive radar. It is shown that non-linear distortions can be successfully mitigated at system level in the digital domain, thereby decreasing the bit error rate of distorted modulated signals and reducing the amount of non-linearly induced interference. Finally, the effective linearity of the front-end is increased substantially. Thus, the proper operation of a low-cost radio under presence of receiver non-linearity is possible. Due to the flexible design, the algorithm is generally applicable for wideband receivers and is not restricted to software defined radios

Temporal Processing by Caenorhabditis elegans Sensory Neurons

Caenorhabditis elegans is a promising organism for trying to understand how nervous systems generate real-time behavior. Its low neuron count suggests that we may be able to observe all of the constituents of the computation of sophisticated sensorimotor behavior. However, its appropriateness as a system for quantitative dynamical study has yet to be established. We show that C. elegans chemosensory neurons can operate in a highly deterministic and low-noise mode, and they act as reliable linear filters of their input. We then use dynamical systems analysis in combination with classical genetic perturbation to uncover cellular and circuit mechanisms of temporal processing. This work should firmly establish C. elegans as a viable platform for applying quantitative dynamical systems methods to understanding how a nervous system processes sensory information, integrates it with an evolving internal state, and produces goal-directed, coordinated behavior

Investigations on the Influence of Acoustics on Live Music Performance using Virtual Acoustic Methods

Room acoustic conditions are an inherent element of every live music performance. They interact with the sound that is generated by the musicians, modifying the characteristics of the sound received by audience and musicians. While listeners usually play a passive role in the context of a live performance, musicians are part of a feedback loop composed by themselves, their instruments, and the room. The goal of this thesis is to characterize the effects of room acoustics in live performances, by studying the acoustical preferences of musicians and characterizing potential performance adjustments implemented by solo players while adapting their interpretation to the room acoustic conditions. To conduct systematic experiments, a virtual acoustic environment that replicates acoustic conditions of real rooms in laboratory conditions is implemented. Room impulse responses of performance rooms are measured and parametrized using spatial measurement techniques. The responses are later resynthesized and convolved in real-time with the sound generated by a musician. The resulting sound is reproduced through a 3D loudspeaker set-up, allowing musicians to perform under replicated acoustic conditions of measured rooms in real-time. The system is used to conduct pilot studies on stage acoustics preferences of semi-professional trumpet players, and to study the impact of room acoustics on potential performance adjustments of live performance. To this end, musical pieces are recorded under different acoustic conditions and later analyzed. A second experiment is performed with organ players in the Detmold Konzerthaus. The reverberation time of the hall is modified using a reverberation enhancement system, and live performances are recorded under different acoustic conditions using a MIDI interface. Similarly to the trumpet players, the recordings are analyzed to evaluate the extent of the performance adjustments. Finally, listening tests are conducted to assess the perceived impact of those adjustments by listeners. Results of the experiments suggest that musicians systematically adjust their performance to accommodate room acoustic conditions and listeners are generally able to perceive these changes. Trumpet players tend to decrease the sound level and sound brightness when exposed to longer and stronger reverberation. Some players adjust as well musical dynamics and aspects related to the tempo of their performance, although generalized trends are not observed. Dry environments are usually preferred to practice instrument technique, while longer reverberation times are preferred in concert conditions. Additionally, the presence of a sufficient amount of early energy contributes positively to the musicians’ comfort, regardless of the direction of incidence of this sound energy. Organ players are prone to modifying the temporal aspects of the performance, generally decreasing the overall tempo and increasing the length of breaks in more reverberant environments. The musical character of the played excerpts seems to play an important role, and while for some pieces changes are generalized and systematic, the performance of other pieces with soft dynamics and little contrast is generally less affected by room acoustics.Raumakustische Bedingungen sind ein inhärentes Element jeder Live-Musik-Darbietung. Sie interagieren mit dem Schall, der von den Musikern erzeugt wird, und modifizieren die Eigenschaften des Klangs, der von Publikum und Musikern empfangen wird. Während Hörer in der Regel eine passive Rolle im Kontext einer Live-Performance spielen, sind Musiker Teil einer Rückkopplungsschleife, die von ihnen selbst, ihren Instrumenten und dem Raum zusammengesetzt ist. Ziel dieser Arbeit ist es, die Effekte der Raumakustik in Live-Auftritten zu charakterisieren, indem die akustischen Präferenzen von Musikern studiert und potenzielle Leistungsanpassungen von Solo-Spielern charakterisiert werden während diese ihre Interpretation an die raumakustischen Bedingungen anpassen. Um systematische Experimente durchzuführen zu können, wird eine virtuelle akustische Umgebung implementiert, indem die akustischen Bedingungen realer Räume unter Laborbedingungen repliziert werden. Raumimpulsantworten von Aufführungsräumen werden mit einem Mikrofon-Array gemessen und analysiert. Die Antworten werden später neu synthetisiert und in Echtzeit mit dem von einem Musiker erzeugten Klang gefaltet. Der resultierende Klang wird von einer 3D-Lautsprecheranordnung wiedergegeben, so dass Musiker unter replizierten akustischen Bedingungen der gemessenen Räume in Echtzeit spielen können. Das System wird verwendet, um Pilotstudien zur Bühnenakustik-Präferenz semiprofessioneller Trompetenspieler durchzuführen und die Auswirkungen der Raumakustik auf potenzielle Anpassungen des Spiels bei Live-Darbietungen zu untersuchen. Zu diesem Zweck werden Musikstücke unter verschiedenen akustischen Bedingungen aufgezeichnet und später automatisch analysiert. Ein zweites Experiment mit Orgelmusik wird im Konzerthaus Detmold durchgeführt. Die Nachhallzeit des Konzerthauses wird mit dem Raumakustik-Sytem Vivace modifiziert, und Live-Aufführungen werden unter verschiedenen akustischen Bedingungen mit einer MIDI-Schnittstelle aufgezeichnet. Ähnlich wie bei den Trompetenspielern werden die Aufnahmen analysiert, um das Ausmaß der Anpassungen des Spiels zu bewerten. Schließlich werden Hörversuche durchgeführt, um die wahrgenommenen Auswirkungen dieser Anpassungen auf die Zuhörer zu beurteilen. Die Ergebnisse der Experimente deuten darauf hin, dass Musiker systematisch ihre Spielweise anpassen, um raumakustische Bedingungen zu berücksichtigen. Zuhörer können diese Veränderungen in der Regel wahrnehmen. Trompetenspieler neigen dazu, den Schallpegel und die Klanghelligkeit zu verringern, wenn sie in längerem und stärkerem Nachhall ausgesetzt sind. Einige Spieler passen auch dynamische und zeitliche Aspekte ihres Spiels an. Trockene Umgebungen werden in der Regel bevorzugt, um die Spieltechnik zu verbessern, während längere Nachhallzeiten bei Konzerten bevorzugt werden. Darüber hinaus trägt das Vorhandensein einer ausreichenden Menge an frühe Schallenergie positiv zum Befinden der Musiker bei, unabhängig von der Einfallsrichtung dieser Schallanteile. Organisten sind empfindlich für zeitliche Änderungen ihres Spiel; in der Regel senken Sie das Tempo und erhöhen die Pausenlänge in Umgebungen mit längerem Nachhall. Der musikalische Charakter der gespiegelten Musikstücke scheint eine wichtige Rolle zu spielen: während für einige Stücke Änderungen einheitlich und systematisch sind, ist die Spielweise anderer Stücke mit geringerer Dynamik und weniger Kontrast in der Regel weniger von der Raumakustik betroffen

Breathing pattern characterization in patients with respiratory and cardiac failure

El objetivo principal de la tesis es estudiar los patrones respiratorios de pacientes en proceso de extubación y pacientes con insuficiencia cardiaca crónica (CHF), a partirde la señal de flujo respiratorio. La información obtenida de este estudio puede contribuir a la comprensión de los procesos fisiológicos subyacentes,y ayudar en el diagnóstico de estos pacientes. Uno de los problemas más desafiantes en unidades de cuidados intensivos es elproceso de desconexión de pacientes asistidos mediante ventilación mecánica. Más del 10% de pacientes que se extuban tienen que ser reintubados antes de 48 horas. Una prueba fallida puede ocasionar distrés cardiopulmonar y una mayor tasa de mortalidad. Se caracterizó el patrón respiratorio y la interacción dinámica entre la frecuenciacardiaca y frecuencia respiratoria, para obtener índices no invasivos que proporcionen una mayor información en el proceso de destete y mejorar el éxito de la desconexión.Las señales de flujo respiratorio y electrocardiográfica utilizadas en este estudio fueron obtenidas durante 30 minutos aplicando la prueba de tubo en T. Se compararon94 pacientes que tuvieron éxito en el proceso de extubación (GE), 39 pacientes que fracasaron en la prueba al mantener la respiración espontánea (GF), y 21 pacientes quesuperaron la prueba con éxito y fueron extubados, pero antes de 48 horas tuvieron que ser reintubados (GR). El patrón respiratorio se caracterizó a partir de las series temporales. Se aplicó la dinámica simbólica conjunta a las series correspondientes a las frecuencias cardiaca y respiratoria, para describir las interacciones cardiorrespiratoria de estos pacientes. Técnicas de "clustering", ecualización del histograma, clasificación mediante máquinasde soporte vectorial (SVM) y técnicas de validación permitieron seleccionar el conjunto de características más relevantes. Se propuso una nueva métrica B (índice de equilibrio) para la optimización de la clasificación con muestras desbalanceadas. Basado en este nuevo índice, aplicando SVM, se seleccionaron las mejores características que mantenían el mejor equilibrio entre sensibilidad y especificidad en todas las clasificaciones. El mejor resultado se obtuvo considerando conjuntamente la precisión y el valor de B, con una clasificación del 80% entre los grupos GE y GF, con 6 características. Clasificando GE vs. el resto de los pacientes, el mejor resultado se obtuvo con 9 características, con 81%. Clasificando GR vs. GE y GR vs. el resto de pacientes la precisión fue del 83% y 81% con 9 y 10 características, respectivamente. La tasa de mortalidad en pacientes con CHF es alta y la estratificación de estospacientes en función del riesgo es uno de los principales retos de la cardiología contemporánea. Estos pacientes a menudo desarrollan patrones de respiraciónperiódica (PB) incluyendo la respiración de Cheyne-Stokes (CSR) y respiración periódica sin apnea. La respiración periódica en estos pacientes se ha asociadocon una mayor mortalidad, especialmente en pacientes con CSR. Por lo tanto, el estudio de estos patrones respiratorios podría servir como un marcador de riesgo y proporcionar una mayor información sobre el estado fisiopatológico de pacientes con CHF. Se pretende identificar la condición de los pacientes con CHFde forma no invasiva mediante la caracterización y clasificación de patrones respiratorios con PBy respiración no periódica (nPB), y patrón de sujetos sanos, a partir registros de 15minutos de la señal de flujo respiratorio. Se caracterizó el patrón respiratorio mediante un estudio tiempo-frecuencia estacionario y no estacionario, de la envolvente de la señal de flujo respiratorio. Parámetros relacionados con la potencia espectral de la envolvente de la señal presentaron losmejores resultados en la clasificación de sujetos sanos y pacientes con CHF con CSR, PB y nPB. Las curvas ROC validan los resultados obtenidos. Se aplicó la "correntropy" para una caracterización tiempo-frecuencia mas completa del patrón respiratorio de pacientes con CHF. La "corretronpy" considera los momentos estadísticos de orden superior, siendo más robusta frente a los "outliers". Con la densidad espectral de correntropy (CSD) tanto la frecuencia de modulación como la dela respiración se representan en su posición real en el eje frecuencial. Los pacientes con PB y nPB, presentan diferentesgrados de periodicidad en función de su condición, mientras que los sujetos sanos no tienen periodicidad marcada. Con único parámetro se obtuvieron resultados del 88.9% clasificando pacientes PB vs. nPB, 95.2% para CHF vs. sanos, 94.4% para nPB vs. sanos.The main objective of this thesis is to study andcharacterize breathing patterns through the respiratory flow signal applied to patients on weaning trials from mechanicalventilation and patients with chronic heart failure (CHF). The aim is to contribute to theunderstanding of the underlying physiological processes and to help in the diagnosis of these patients. One of the most challenging problems in intensive care units is still the process ofdiscontinuing mechanical ventilation, as over 10% of patients who undergo successfulT-tube trials have to be reintubated in less than 48 hours. A failed weaning trial mayinduce cardiopulmonary distress and carries a higher mortality rate. We characterize therespiratory pattern and the dynamic interaction between heart rate and breathing rate toobtain noninvasive indices that provide enhanced information about the weaningprocess and improve the weaning outcome. This is achieved through a comparison of 94 patients with successful trials (GS), 39patients who fail to maintain spontaneous breathing (GF), and 21 patients who successfully maintain spontaneous breathing and are extubated, but require thereinstitution of mechanical ventilation in less than 48 hours because they are unable tobreathe (GR). The ECG and the respiratory flow signals used in this study were acquired during T-tube tests and last 30 minute. The respiratory pattern was characterized by means of a number of respiratory timeseries. Joint symbolic dynamics applied to time series of heart rate and respiratoryfrequency was used to describe the cardiorespiratory interactions of patients during theweaning trial process. Clustering, histogram equalization, support vector machines-based classification (SVM) and validation techniques enabled the selection of the bestsubset of input features. We defined a new optimization metric for unbalanced classification problems, andestablished a new SVM feature selection method, based on this balance index B. The proposed B-based SVM feature selection provided a better balance between sensitivityand specificity in all classifications. The best classification result was obtained with SVM feature selection based on bothaccuracy and the balance index, which classified GS and GFwith an accuracy of 80%, considering 6 features. Classifying GS versus the rest of patients, the best result wasobtained with 9 features, 81%, and the accuracy classifying GR versus GS, and GR versus the rest of the patients was 83% and 81% with 9 and 10 features, respectively.The mortality rate in CHF patients remains high and risk stratification in these patients isstill one of the major challenges of contemporary cardiology. Patients with CHF oftendevelop periodic breathing patterns including Cheyne-Stokes respiration (CSR) and periodic breathing without apnea. Periodic breathing in CHF patients is associated withincreased mortality, especially in CSR patients. Therefore it could serve as a risk markerand can provide enhanced information about thepathophysiological condition of CHF patients. The main goal of this research was to identify CHF patients' condition noninvasively bycharacterizing and classifying respiratory flow patterns from patients with PB and nPBand healthy subjects by using 15-minute long respiratory flow signals. The respiratory pattern was characterized by a stationary and a nonstationary time-frequency study through the envelope of the respiratory flow signal. Power-related parameters achieved the best results in all of the classifications involving healthy subjects and CHF patients with CSR, PB and nPB and the ROC curves validated theresults obtained for the identification of different respiratory patterns. We investigated the use of correntropy for the spectral characterization of respiratory patterns in CHF patients. The correntropy function accounts for higher-order moments and is robust to outliers. Due to the former property, the respiratory and modulationfrequencies appear at their actual locations along the frequency axis in the correntropy spectral density (CSD). The best results were achieved with correntropy and CSD-related parameters that characterized the power in the modulation and respiration discriminant bands, definedas a frequency interval centred on the modulation and respiration frequency peaks,respectively. All patients, i.e. both PB and nPB, exhibit various degrees of periodicitydepending on their condition, whereas healthy subjects have no pronounced periodicity.This fact led to excellent results classifying PB and nPB patients 88.9%, CHF versushealthy 95.2%, and nPB versus healthy 94.4% with only one parameter.Postprint (published version

Proceedings of the EAA Spatial Audio Signal Processing symposium: SASP 2019

International audienc