Using graphical models and multi-attribute utility theory for probabilistic uncertainty handling in large systems, with application to nuclear emergency management

Although many decision-making problems involve uncertainty, uncertainty handling within large decision support systems (DSSs) is challenging. One domain where uncertainty handling is critical is emergency response management, in particular nuclear emergency response, where decision making takes place in an uncertain, dynamically changing environment. Assimilation and analysis of data can help to reduce these uncertainties, but it is critical to do this in an efficient and defensible way. After briefly introducing the structure of a typical DSS for nuclear emergencies, the paper sets up a theoretical structure that enables a formal Bayesian decision analysis to be performed for environments like this within a DSS architecture. In such probabilistic DSSs many input conditional probability distributions are provided by different sets of experts overseeing different aspects of the emergency. These probabilities are then used by the decision maker (DM) to find her optimal decision. We demonstrate in this paper that unless due care is taken in such a composite framework, coherence and rationality may be compromised in a sense made explicit below. The technology we describe here builds a framework around which Bayesian data updating can be performed in a modular way, ensuring both coherence and efficiency, and provides sufficient unambiguous information to enable the DM to discover her expected utility maximizing policy

Structure Learning in Coupled Dynamical Systems and Dynamic Causal Modelling

Identifying a coupled dynamical system out of many plausible candidates, each of which could serve as the underlying generator of some observed measurements, is a profoundly ill posed problem that commonly arises when modelling real world phenomena. In this review, we detail a set of statistical procedures for inferring the structure of nonlinear coupled dynamical systems (structure learning), which has proved useful in neuroscience research. A key focus here is the comparison of competing models of (ie, hypotheses about) network architectures and implicit coupling functions in terms of their Bayesian model evidence. These methods are collectively referred to as dynamical casual modelling (DCM). We focus on a relatively new approach that is proving remarkably useful; namely, Bayesian model reduction (BMR), which enables rapid evaluation and comparison of models that differ in their network architecture. We illustrate the usefulness of these techniques through modelling neurovascular coupling (cellular pathways linking neuronal and vascular systems), whose function is an active focus of research in neurobiology and the imaging of coupled neuronal systems

Prescriptive Analytics in Procurement: Reducing Process Costs

In obtaining low-cost goods, the indirect expenses associated with sourcing suppliers can be substantial compared to the potential advantages of lower direct purchase costs. We addressed this problem as an exploration vs. exploitation trade-off. The proposed methodology uses a Bayesian technique to learn a stochastically optimal sourcing strategy directly from quotation data. We illustrate our approach using real quotation data for the procurement of electronic resistors (n=201,187). Rather than making optimal predictions, we concentrate on making optimal decisions. In doing so, we offered a significant improvement in purchase and procurement process costs. Our model is also more robust to prediction errors

Efficient and automatic methods for flexible regression on spatiotemporal data, with applications to groundwater monitoring

Fitting statistical models to spatiotemporal data requires finding the right balance between imposing smoothness and following the data. In the context of P-splines, we propose a Bayesian framework for choosing the smoothing parameter which allows the construction of fully-automatic data-driven methods for fitting flexible models to spatiotemporal data. An implementation, which is highly computationally efficient and which exploits the sparsity of the design and penalty matrices, is proposed. The findings are illustrated using a simulation study and two examples, all concerned with the modelling of contaminants in groundwater. This suggests that the proposed strategy is more stable that competing methods based on the use of criteria such as GCV and AIC