3,846 research outputs found
Bayesian Recurrent Neural Network Models for Forecasting and Quantifying Uncertainty in Spatial-Temporal Data
Recurrent neural networks (RNNs) are nonlinear dynamical models commonly used
in the machine learning and dynamical systems literature to represent complex
dynamical or sequential relationships between variables. More recently, as deep
learning models have become more common, RNNs have been used to forecast
increasingly complicated systems. Dynamical spatio-temporal processes represent
a class of complex systems that can potentially benefit from these types of
models. Although the RNN literature is expansive and highly developed,
uncertainty quantification is often ignored. Even when considered, the
uncertainty is generally quantified without the use of a rigorous framework,
such as a fully Bayesian setting. Here we attempt to quantify uncertainty in a
more formal framework while maintaining the forecast accuracy that makes these
models appealing, by presenting a Bayesian RNN model for nonlinear
spatio-temporal forecasting. Additionally, we make simple modifications to the
basic RNN to help accommodate the unique nature of nonlinear spatio-temporal
data. The proposed model is applied to a Lorenz simulation and two real-world
nonlinear spatio-temporal forecasting applications
Two-stage Bayesian model to evaluate the effect of air pollution on chronic respiratory diseases using drug prescriptions
Exposure to high levels of air pollutant concentration is known to be associated with respiratory problems which can translate into higher morbidity and mortality rates. The link between air pollution and population health has mainly been assessed considering air quality and hospitalisation or mortality data. However, this approach limits the analysis to individuals characterised by severe conditions. In this paper we evaluate the link between air pollution and respiratory diseases using general practice drug prescriptions for chronic respiratory diseases, which allow to draw conclusions based on the general population.
We propose a two-stage statistical approach: in the first stage we specify a space-time model to estimate the monthly NO2 concentration integrating several data sources characterised by different spatio-temporal resolution; in the second stage we link the concentration to the β2-agonists prescribed monthly by general practices in England and we model the prescription rates through a small area approach
Recent Trends in Modelling Spatio-Temporal Data
Il lavoro fornisce una disamina delle pi`u recenti metodologie proposte nell’ambito dei modelli spazio-temporali. Nel tentativo di proporre una visione unificata delle metodologie trattate, viene fornita prima una descrizione dei vari tipi di dati spazio-temporali.
Successivamente, si procede con la discussione dei modelli per processi spazialmente continui. La modellistica spazio-temporale `e stata largamente utilizzata per affrontare
problemi in ambito ambientale, geostatistico, idrologico e meteorologico. Questo articolo fornisce una analisi dei metodi correntemente applicati in molte di queste aree
Data-driven modelling of biological multi-scale processes
Biological processes involve a variety of spatial and temporal scales. A
holistic understanding of many biological processes therefore requires
multi-scale models which capture the relevant properties on all these scales.
In this manuscript we review mathematical modelling approaches used to describe
the individual spatial scales and how they are integrated into holistic models.
We discuss the relation between spatial and temporal scales and the implication
of that on multi-scale modelling. Based upon this overview over
state-of-the-art modelling approaches, we formulate key challenges in
mathematical and computational modelling of biological multi-scale and
multi-physics processes. In particular, we considered the availability of
analysis tools for multi-scale models and model-based multi-scale data
integration. We provide a compact review of methods for model-based data
integration and model-based hypothesis testing. Furthermore, novel approaches
and recent trends are discussed, including computation time reduction using
reduced order and surrogate models, which contribute to the solution of
inference problems. We conclude the manuscript by providing a few ideas for the
development of tailored multi-scale inference methods.Comment: This manuscript will appear in the Journal of Coupled Systems and
Multiscale Dynamics (American Scientific Publishers
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