Towards Automatic Generation of Shareable Synthetic Clinical Notes Using Neural Language Models

Large-scale clinical data is invaluable to driving many computational scientific advances today. However, understandable concerns regarding patient privacy hinder the open dissemination of such data and give rise to suboptimal siloed research. De-identification methods attempt to address these concerns but were shown to be susceptible to adversarial attacks. In this work, we focus on the vast amounts of unstructured natural language data stored in clinical notes and propose to automatically generate synthetic clinical notes that are more amenable to sharing using generative models trained on real de-identified records. To evaluate the merit of such notes, we measure both their privacy preservation properties as well as utility in training clinical NLP models. Experiments using neural language models yield notes whose utility is close to that of the real ones in some clinical NLP tasks, yet leave ample room for future improvements.Comment: Clinical NLP Workshop 201

Use of Artificial Intelligence in Healthcare Delivery

In recent years, there has been an amplified focus on the use of artificial intelligence (AI) in various domains to resolve complex issues. Likewise, the adoption of artificial intelligence (AI) in healthcare is growing while radically changing the face of healthcare delivery. AI is being employed in a myriad of settings including hospitals, clinical laboratories, and research facilities. AI approaches employing machines to sense and comprehend data like humans has opened up previously unavailable or unrecognised opportunities for clinical practitioners and health service organisations. Some examples include utilising AI approaches to analyse unstructured data such as photos, videos, physician notes to enable clinical decision making; use of intelligence interfaces to enhance patient engagement and compliance with treatment; and predictive modelling to manage patient flow and hospital capacity/resource allocation. Yet, there is an incomplete understanding of AI and even confusion as to what it is? Also, it is not completely clear what the implications are in using AI generally and in particular for clinicians? This chapter aims to cover these topics and also introduce the reader to the concept of AI, the theories behind AI programming and the various applications of AI in the medical domain

Special Libraries, February 1966

Volume 57, Issue 2https://scholarworks.sjsu.edu/sla_sl_1966/1001/thumbnail.jp

Opportunities for Business Intelligence and Big Data Analytics in Evidence Based Medicine

Evidence based medicine (EBM) is the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients. Each year, a significant number of research studies (potentially serving as evidence) are reported in the literature at an ever-increasing rate outpacing the translation of research findings into practice. Coupled with the proliferation of electronic health records, and consumer health information, researchers and practitioners are challenged to leverage the full potential of EBM. In this paper we present a research agenda for leveraging business intelligence and big data analytics in evidence based medicine, and illustrate how analytics can be used to support EBM

HOLMeS: eHealth in the Big Data and Deep Learning Era

Now, data collection and analysis are becoming more and more important in a variety of application domains, as long as novel technologies advance. At the same time, we are experiencing a growing need for human–machine interaction with expert systems, pushing research toward new knowledge representation models and interaction paradigms. In particular, in the last few years, eHealth—which usually indicates all the healthcare practices supported by electronic elaboration and remote communications—calls for the availability of a smart environment and big computational resources able to offer more and more advanced analytics and new human–computer interaction paradigms. The aim of this paper is to introduce the HOLMeS (health online medical suggestions) system: A particular big data platform aiming at supporting several eHealth applications. As its main novelty/functionality, HOLMeS exploits a machine learning algorithm, deployed on a cluster-computing environment, in order to provide medical suggestions via both chat-bot and web-app modules, especially for prevention aims. The chat-bot, opportunely trained by leveraging a deep learning approach, helps to overcome the limitations of a cold interaction between users and software, exhibiting a more human-like behavior. The obtained results demonstrate the effectiveness of the machine learning algorithms, showing an area under ROC (receiver operating characteristic) curve (AUC) of 74.65% when some first-level features are used to assess the occurrence of different chronic diseases within specific prevention pathways. When disease-specific features are added, HOLMeS shows an AUC of 86.78%, achieving a greater effectiveness in supporting clinical decisions

Antecedents and Catalysts for Developing a Healthcare Analytic Capability

Analytics is the most advanced component of business intelligence. An analytic capability enables fact-based decisions using quantitative models. These models draw on statistical and quantitative analysis of large data repositories. An analytic capability is especially critical in healthcare because lives are at stake and there is intense pressure to reduce costs and improve efficiency. This study proposes antecedents and catalysts for developing an analytic capability based on an in-depth study of the cardiac surgical programs of the Veterans Health Administration (VHA). The VHA has developed an analytic capability for patient treatment and administrative decision-making. The models rely on the input of clinical data from multiple facilities. However, a diversity of standards, infrastructure, staff and patient mix result in misunderstood data definitions, errors in data entry, incomplete data sets, and conflicts between multiple systems. Consequently, data aggregation and data interoperability at both the systemic and semantic levels are challenging. Catalysts for developing an analytic capability, derived from the VHA case study, include a community of practice and patient case reassessment practices. Antecedents of an analytic capability include robust data aggregation and cleaning practices and establishment of data standards followed by judicious tailoring of analytic outputs to decision making needs

Logic Programming Applications: What Are the Abstractions and Implementations?

This article presents an overview of applications of logic programming, classifying them based on the abstractions and implementations of logic languages that support the applications. The three key abstractions are join, recursion, and constraint. Their essential implementations are for-loops, fixed points, and backtracking, respectively. The corresponding kinds of applications are database queries, inductive analysis, and combinatorial search, respectively. We also discuss language extensions and programming paradigms, summarize example application problems by application areas, and touch on example systems that support variants of the abstractions with different implementations