Interactive attention network for adverse drug reaction classification

© Springer Nature Switzerland AG 2018. Detection of new adverse drug reactions is intended to both improve the quality of medications and drug reprofiling. Social media and electronic clinical reports are becoming increasingly popular as a source for obtaining the health-related information, such as identification of adverse drug reactions. One of the tasks of extracting adverse drug reactions from social media is the classification of entities that describe the state of health. In this paper, we investigate the applicability of Interactive Attention Network for identification of adverse drug reactions from user reviews. We formulate this problem as a binary classification task. We show the effectiveness of this method on a number of publicly available corpora

UNSUPERVISED DYNAMIC TOPIC MODEL FOR EXTRACTING ADVERSE DRUG REACTION FROM HEALTH FORUMS

The relationship between drug and its side effects has been outlined in two websites: Sider and WebMD. The aim of this study was to find the association between drug and its side effects. We compared the reports of typical users of a web site called: "Ask a patient" website with reported drug side effects in reference sites such as Sider and WebMD. In addition, the typical users' comments on highly-commented drugs (Neurotic drugs, Anti-Pregnancy drugs and Gastrointestinal drugs) were analyzed, using deep learning method. To this end, typical users' comments on drugs' side effects, during last decades, were collected from the website “Ask a patient”. Then, the data on drugs were classified based on deep learning model (HAN) and the drugs' side effect. And the main topics of side effects for each group of drugs were identified and reported, through Sider and WebMD websites. Our model demonstrates its ability to accurately describe and label side effects in a temporal text corpus by a deep learning classifier which is shown to be an effective method to precisely discover the association between drugs and their side effects. Moreover, this model has the capability to immediately locate information in reference sites to recognize the side effect of new drugs, applicable for drug companies. This study suggests that the sensitivity of internet users and the diverse scientific findings are for the benefit of dis¬tinct detection of adverse effects of drugs, and deep learning would facilitate it