Automated detection of brain abnormalities in neonatal hypoxia ischemic injury from MR images.

We compared the efficacy of three automated brain injury detection methods, namely symmetry-integrated region growing (SIRG), hierarchical region splitting (HRS) and modified watershed segmentation (MWS) in human and animal magnetic resonance imaging (MRI) datasets for the detection of hypoxic ischemic injuries (HIIs). Diffusion weighted imaging (DWI, 1.5T) data from neonatal arterial ischemic stroke (AIS) patients, as well as T2-weighted imaging (T2WI, 11.7T, 4.7T) at seven different time-points (1, 4, 7, 10, 17, 24 and 31 days post HII) in rat-pup model of hypoxic ischemic injury were used to assess the temporal efficacy of our computational approaches. Sensitivity, specificity, and similarity were used as performance metrics based on manual ('gold standard') injury detection to quantify comparisons. When compared to the manual gold standard, automated injury location results from SIRG performed the best in 62% of the data, while 29% for HRS and 9% for MWS. Injury severity detection revealed that SIRG performed the best in 67% cases while 33% for HRS. Prior information is required by HRS and MWS, but not by SIRG. However, SIRG is sensitive to parameter-tuning, while HRS and MWS are not. Among these methods, SIRG performs the best in detecting lesion volumes; HRS is the most robust, while MWS lags behind in both respects

A Unified Framework for Compositional Fitting of Active Appearance Models

Active Appearance Models (AAMs) are one of the most popular and well-established techniques for modeling deformable objects in computer vision. In this paper, we study the problem of fitting AAMs using Compositional Gradient Descent (CGD) algorithms. We present a unified and complete view of these algorithms and classify them with respect to three main characteristics: i) cost function; ii) type of composition; and iii) optimization method. Furthermore, we extend the previous view by: a) proposing a novel Bayesian cost function that can be interpreted as a general probabilistic formulation of the well-known project-out loss; b) introducing two new types of composition, asymmetric and bidirectional, that combine the gradients of both image and appearance model to derive better conver- gent and more robust CGD algorithms; and c) providing new valuable insights into existent CGD algorithms by reinterpreting them as direct applications of the Schur complement and the Wiberg method. Finally, in order to encourage open research and facilitate future comparisons with our work, we make the implementa- tion of the algorithms studied in this paper publicly available as part of the Menpo Project.Comment: 39 page

Asymmetric Feature Maps with Application to Sketch Based Retrieval

We propose a novel concept of asymmetric feature maps (AFM), which allows to evaluate multiple kernels between a query and database entries without increasing the memory requirements. To demonstrate the advantages of the AFM method, we derive a short vector image representation that, due to asymmetric feature maps, supports efficient scale and translation invariant sketch-based image retrieval. Unlike most of the short-code based retrieval systems, the proposed method provides the query localization in the retrieved image. The efficiency of the search is boosted by approximating a 2D translation search via trigonometric polynomial of scores by 1D projections. The projections are a special case of AFM. An order of magnitude speed-up is achieved compared to traditional trigonometric polynomials. The results are boosted by an image-based average query expansion, exceeding significantly the state of the art on standard benchmarks.Comment: CVPR 201

Direct Measurement of Neutron-Star Recoil in the Oxygen-Rich Supernova Remnant Puppis A

A sequence of three Chandra X-ray Observatory High Resolution Camera images taken over a span of five years reveals arc-second-scale displacement of RX J0822-4300, the stellar remnant (presumably a neutron star) near the center of the Puppis A supernova remnant. We measure its proper motion to be 0.165+/-0.025 arcsec/yr toward the west-southwest. At a distance of 2 kpc, this corresponds to a transverse space velocity of ~1600 km/s. The space velocity is consistent with the explosion center inferred from proper motions of the oxygen-rich optical filaments, and confirms the idea that Puppis A resulted from an asymmetric explosion accompanied by a kick that imparted roughly 3*10^49 ergs of kinetic energy (some 3 percent of the kinetic energy for a typical supernova) to the stellar remnant. We discuss constraints on core-collapse supernova models that have been proposed to explain neutron star kick velocities

Strain-gradient-induced magnetic anisotropy in straight-stripe mixed-phase bismuth ferrites: An insight into flexomagnetic phenomenon

Implementation of antiferromagnetic compounds as active elements in spintronics has been hindered by their insensitive nature against external perturbations which causes difficulties in switching among different antiferromagnetic spin configurations. Electrically-controllable strain gradient can become a key parameter to tune the antiferromagnetic states of multiferroic materials. We have discovered a correlation between an electrically-written straight-stripe mixed-phase boundary and an in-plane antiferromagnetic spin axis in highly-elongated La-5%-doped BiFeO$_{3}$ thin films by performing polarization-dependent photoemission electron microscopy in conjunction with cluster model calculations. Model Hamiltonian calculation for the single-ion anisotropy including the spin-orbit interaction has been performed to figure out the physical origin of the link between the strain gradient present in the mixed phase area and its antiferromagnetic spin axis. Our findings enable estimation of the strain-gradient-induced magnetic anisotropy energy per Fe ion at around 5$\times$10$^{-12}$ eV m, and provide a new pathway towards an electric-field-induced 90$^{\circ}$ rotation of antiferromagnetic spin axis at room temperature by flexomagnetism.Comment: 32 pages, 5 figure