Hyperspectral colon tissue cell classification

A novel algorithm to discriminate between normal and malignant tissue cells of the human colon is presented. The microscopic level images of human colon tissue cells were acquired using hyperspectral imaging technology at contiguous wavelength intervals of visible light. While hyperspectral imagery data provides a wealth of information, its large size normally means high computational processing complexity. Several methods exist to avoid the so-called curse of dimensionality and hence reduce the computational complexity. In this study, we experimented with Principal Component Analysis (PCA) and two modifications of Independent Component Analysis (ICA). In the first stage of the algorithm, the extracted components are used to separate four constituent parts of the colon tissue: nuclei, cytoplasm, lamina propria, and lumen. The segmentation is performed in an unsupervised fashion using the nearest centroid clustering algorithm. The segmented image is further used, in the second stage of the classification algorithm, to exploit the spatial relationship between the labeled constituent parts. Experimental results using supervised Support Vector Machines (SVM) classification based on multiscale morphological features reveal the discrimination between normal and malignant tissue cells with a reasonable degree of accuracy

Fourth Moments and Independent Component Analysis

In independent component analysis it is assumed that the components of the observed random vector are linear combinations of latent independent random variables, and the aim is then to find an estimate for a transformation matrix back to these independent components. In the engineering literature, there are several traditional estimation procedures based on the use of fourth moments, such as FOBI (fourth order blind identification), JADE (joint approximate diagonalization of eigenmatrices), and FastICA, but the statistical properties of these estimates are not well known. In this paper various independent component functionals based on the fourth moments are discussed in detail, starting with the corresponding optimization problems, deriving the estimating equations and estimation algorithms, and finding asymptotic statistical properties of the estimates. Comparisons of the asymptotic variances of the estimates in wide independent component models show that in most cases JADE and the symmetric version of FastICA perform better than their competitors.Comment: Published at http://dx.doi.org/10.1214/15-STS520 in the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org

Diesel engine fuel injection monitoring using acoustic measurements and independent component analysis

Air-borne acoustic based condition monitoring is a promising technique because of its intrusive nature and the rich information contained within the acoustic signals including all sources. However, the back ground noise contamination, interferences and the number of Internal Combustion Engine ICE vibro-acoustic sources preclude the extraction of condition information using this technique. Therefore, lower energy events; such as fuel injection, are buried within higher energy events and/or corrupted by background noise. This work firstly investigates diesel engine air-borne acoustic signals characteristics and the benefits of joint time-frequency domain analysis. Secondly, the air-borne acoustic signals in the vicinity of injector head were recorded using three microphones around the fuel injector (120° apart from each other) and an Independent Component Analysis (ICA) based scheme was developed to decompose these acoustic signals. The fuel injection process characteristics were thus revealed in the time-frequency domain using Wigner-Ville distribution (WVD) technique. Consequently the energy levels around the injection process period between 11 and 5 degrees before the top dead center and of frequency band 9 to 15 kHz are calculated. The developed technique was validated by simulated signals and empirical measurements at different injection pressure levels from 250 to 210 bars in steps of 10 bars. The recovered energy levels in the tested conditions were found to be affected by the injector pressure settings