Temporal reasoning in a logic programming language with modularity

Actualmente os Sistemas de Informação Organizacionais (SIO) lidam cada vez mais com informação que tem dependências temporais. Neste trabalho concebemos um ambiente de trabalho para construir e manter SIO Temporais. Este ambiente assenta sobre um linguagem lógica denominada Temporal Contextua) Logic Programming que integra modularidade com raciocínio temporal fazendo com que a utilização de um módulo dependa do tempo do contexto. Esta linguagem é a evolução de uma outra, também introduzida nesta tese, que combina Contextua) Logic Programming com Temporal Annotated Constraint Logic Programming, na qual a modularidade e o tempo são características ortogonais. Ambas as linguagens são formalmente discutidas e exemplificadas. As principais contribuições do trabalho descrito nesta tese incluem: • Optimização de Contextua) Logic Programming (CxLP) através de interpretação abstracta. • Sintaxe e semântica operacional para uma linguagem que combina de um modo independente as linguagens Temporal Annotated Constraint Logic Programming (TACLP) e CxLP. É apresentado um compilador para esta linguagem. • Linguagem (sintaxe e semântica) que integra de um modo inovador modularidade (CxLP) com raciocínio temporal (TACLP). Nesta linguagem a utilização de um dado módulo está dependente do tempo do contexto. É descrito um interpretador e um compilador para esta linguagem. • Ambiente de trabalho para construir e fazer a manutenção de SIO Temporais. Assenta sobre uma especificação revista da linguagem ISCO, adicionando classes e manipulação de dados temporais. É fornecido um compilador em que a linguagem resultante é a descrita no item anterior. ABSTRACT- Current Organisational Information Systems (OIS) deal with more and more Infor-mation that, is time dependent. In this work we provide a framework to construct and maintain Temporal OIS. This framework builds upon a logical language called Temporal Contextual. Logic Programming that deeply integrates modularity with tem-poral reasoning making the usage of a module time dependent. This language is an evolution of another one, also introduced in this thesis, that combines Contextual Logic Programming with Temporal Annotated Constraint Logic Programming where modularity and time are orthogonal features. Both languages are formally discussed and illustrated. The main contributions of the work described in this thesis include: • Optimisation of Contextual Logic Programming (CxLP) through abstract interpretation. • Syntax and operational semantics for an independent combination of the temporal framework Temporal Annotated Constraint Logic Programming (TACLP) and CxLP. A compiler for this language is also provided. • Language (syntax and semantics) that integrates in a innovative way modularity (CxLP) with temporal reasoning (TACLP). In this language the usage of a given module depends of the time of the context. An interpreter and a compiler for this language are described. • Framework to construct and maintain Temporal Organisational Information Systems. It builds upon a revised specification of the language ISCO, adding temporal classes and temporal data manipulation. A compiler targeting the language presented in the previous item is also given

Categorical Ontology of Complex Systems, Meta-Systems and Theory of Levels: The Emergence of Life, Human Consciousness and Society

Single cell interactomics in simpler organisms, as well as somatic cell interactomics in multicellular organisms, involve biomolecular interactions in complex signalling pathways that were recently represented in modular terms by quantum automata with ‘reversible behavior’ representing normal cell cycling and division. Other implications of such quantum automata, modular modeling of signaling pathways and cell differentiation during development are in the fields of neural plasticity and brain development leading to quantum-weave dynamic patterns and specific molecular processes underlying extensive memory, learning, anticipation mechanisms and the emergence of human consciousness during the early brain development in children. Cell interactomics is here represented for the first time as a mixture of ‘classical’ states that determine molecular dynamics subject to Boltzmann statistics and ‘steady-state’, metabolic (multi-stable) manifolds, together with ‘configuration’ spaces of metastable quantum states emerging from complex quantum dynamics of interacting networks of biomolecules, such as proteins and nucleic acids that are now collectively defined as quantum interactomics. On the other hand, the time dependent evolution over several generations of cancer cells --that are generally known to undergo frequent and extensive genetic mutations and, indeed, suffer genomic transformations at the chromosome level (such as extensive chromosomal aberrations found in many colon cancers)-- cannot be correctly represented in the ‘standard’ terms of quantum automaton modules, as the normal somatic cells can. This significant difference at the cancer cell genomic level is therefore reflected in major changes in cancer cell interactomics often from one cancer cell ‘cycle’ to the next, and thus it requires substantial changes in the modeling strategies, mathematical tools and experimental designs aimed at understanding cancer mechanisms. Novel solutions to this important problem in carcinogenesis are proposed and experimental validation procedures are suggested. From a medical research and clinical standpoint, this approach has important consequences for addressing and preventing the development of cancer resistance to medical therapy in ongoing clinical trials involving stage III cancer patients, as well as improving the designs of future clinical trials for cancer treatments.\ud \ud \ud KEYWORDS: Emergence of Life and Human Consciousness;\ud Proteomics; Artificial Intelligence; Complex Systems Dynamics; Quantum Automata models and Quantum Interactomics; quantum-weave dynamic patterns underlying human consciousness; specific molecular processes underlying extensive memory, learning, anticipation mechanisms and human consciousness; emergence of human consciousness during the early brain development in children; Cancer cell ‘cycling’; interacting networks of proteins and nucleic acids; genetic mutations and chromosomal aberrations in cancers, such as colon cancer; development of cancer resistance to therapy; ongoing clinical trials involving stage III cancer patients’ possible improvements of the designs for future clinical trials and cancer treatments. \ud \u

Universal Gravitation and the (Un)Intelligibility of Natural Philosophy

This article centers on Hume’s position on the intelligibility of natural philosophy. To that end, the controversy surrounding universal gravitation shall be scrutinized. It is very well-known that Hume sides with the Newtonian experimentalist approach rather than with the Leibnizian demand for intelligibility. However, what is not clear is Hume’s overall position on the intelligibility of natural philosophy. It shall be argued that Hume declines Leibniz’s principle of intelligibility. However, Hume does not eschew intelligibility altogether; his concept of causation itself stipulates mechanical intelligibility

Dealing with abstraction: Case study generalisation as a method for eliciting design patterns

Developing a pattern language is a non-trivial problem. A critical requirement is a method to support pattern writers with abstraction, so as they can produce generalised patterns. In this paper, we address this issue by developing a structured process of generalisation. It is important that this process is initiated through engaging participants in identifying initial patterns, i.e. directly dealing with the 'cold-start' problem. We have found that short case study descriptions provide a productive 'way into' the process for participants. We reflect on a 1-year interdisciplinary pan-European research project involving the development of almost 30 cases and over 150 patterns. We provide example cases, detailing the process by which their associated patterns emerged. This was based on a foundation for generalisation from cases with common attributes. We discuss the merits of this approach and its implications for pattern development

Time and the Continuum. An Introduction to the Problem(s)

Philosophy in the 20th Century is usually characterized in terms of the linguistic turn, language being a central topic that cuts across very different philosophical schools (Continental vs Analytic, Phenomenology/ Hermeneutic vs Structuralism and Post-Structuralism, etc.). Yet, looking at its major philosophical, scientific and literal works, we may as well speak of a temporal turn to describe the movement of thinking throughout the century. From Bergson’s Creative Evolution to Heidegger’s Being and Time, from Einstein’s theories of relativity to Prior’s temporal logic, from Proust to Borges, the engagement with time is ubiquitous from the beginning to the end of the Century, tracing an alternative line of thought that runs parallel to that of the engagement with language. And, in fact, this line becomes even more visible and important now, from the perspective of the 21st Century where the linguistic turn seems to have been put aside and the topic of time is even more on the rise. In the last years, publications on the topic have been literally exploding, not just in metaphysics and philosophy of science, but also in the philosophy of mind, the philosophy of action, in ethics, and aesthetics.Philosophy in the 20th Century is usually characterized in terms of the linguistic turn, language being a central topic that cuts across very different philosophical schools (Continental vs Analytic, Phenomenology/ Hermeneutic vs Structuralism and Post-Structuralism, etc.). Yet, looking at its major philosophical, scientific and literal works, we may as well speak of a temporal turn to describe the movement of thinking throughout the century. From Bergson’s Creative Evolution to Heidegger’s Being and Time, from Einstein’s theories of relativity to Prior’s temporal logic, from Proust to Borges, the engagement with time is ubiquitous from the beginning to the end of the Century, tracing an alternative line of thought that runs parallel to that of the engagement with language. And, in fact, this line becomes even more visible and important now, from the perspective of the 21st Century where the linguistic turn seems to have been put aside and the topic of time is even more on the rise. In the last years, publications on the topic have been literally exploding, not just in metaphysics and philosophy of science, but also in the philosophy of mind, the philosophy of action, in ethics, and aesthetics.Philosophy in the 20th Century is usually characterized in terms of the linguistic turn, language being a central topic that cuts across very different philosophical schools (Continental vs Analytic, Phenomenology/ Hermeneutic vs Structuralism and Post-Structuralism, etc.). Yet, looking at its major philosophical, scientific and literal works, we may as well speak of a temporal turn to describe the movement of thinking throughout the century. From Bergson’s Creative Evolution to Heidegger’s Being and Time, from Einstein’s theories of relativity to Prior’s temporal logic, from Proust to Borges, the engagement with time is ubiquitous from the beginning to the end of the Century, tracing an alternative line of thought that runs parallel to that of the engagement with language. And, in fact, this line becomes even more visible and important now, from the perspective of the 21st Century where the linguistic turn seems to have been put aside and the topic of time is even more on the rise. In the last years, publications on the topic have been literally exploding, not just in metaphysics and philosophy of science, but also in the philosophy of mind, the philosophy of action, in ethics, and aesthetics

Invariance: A Tale of Intellectual Migration

The plotline of the standard story told about the development of intellectual history at the end of the 19th/turn of the 20th century follows the move from absolutism to perspectivalism. The narrative takes us, on the one hand, from the scientism of late Enlightenment writers like Voltaire, Mill, D’Alebert, and Comte and the historical determinism of Hegel, all of which were based upon a universal picture of rationality, to, on the other hand, the relativistic physics of Einstein, the perspectival art of Picasso, and the individualism of Nietzsche and Kierkegaard leading to the phenomenology of Husserl and Heidegger to and on through the deconstructivist work of Derrida in which universal proclamations were deemed meaningless. In their place, was relative dependent upon subjective, political, and social factors, influences, and interpretations. Like all sketches, of course, the story is more complicated than that. There is another trend in the intellectual air of the early 20th century that gets left out of this oversimplified picture, one that threads a middle path between absolutism and perspectivalism, a path that considers both frame-dependent or covariant truths and frame-independent or invariant truths and examines the relations between them. Indeed, the notions of covariance and invariance play important roles in the development of the fields of mathematics, physics, philosophy, and psychology in the decades after the turn of the 20th century. The migration of the concepts of invariance and covariance illustrates not only the interconnectedness of the working communities of intellectuals, but also displays ways in which the personal, social, and political overlaps between groups of disciplinary thinkers are essential conduits for the conceptual cross-fertilization that aids in the health of our modern fields of study. [excerpt