Alignment and IT Project Value Maximization

This paper presents a case study of successful ERP implementation in two phases. The second phase included significant efforts to align the business strategy and organizational structure along with the information system components. These efforts enabled the organization to complete its alignment cycle by integrating its IT infrastructure and processes with the organizational infrastructure and processes, as well as fitting business strategy with the new infrastructure and processes and to reap the maximum value

Robust and Fast 3D Scan Alignment using Mutual Information

This paper presents a mutual information (MI) based algorithm for the estimation of full 6-degree-of-freedom (DOF) rigid body transformation between two overlapping point clouds. We first divide the scene into a 3D voxel grid and define simple to compute features for each voxel in the scan. The two scans that need to be aligned are considered as a collection of these features and the MI between these voxelized features is maximized to obtain the correct alignment of scans. We have implemented our method with various simple point cloud features (such as number of points in voxel, variance of z-height in voxel) and compared the performance of the proposed method with existing point-to-point and point-to- distribution registration methods. We show that our approach has an efficient and fast parallel implementation on GPU, and evaluate the robustness and speed of the proposed algorithm on two real-world datasets which have variety of dynamic scenes from different environments

Transcriptome Analyses of Tumor-Adjacent Somatic Tissues Reveal Genes Co-Expressed with Transposable Elements

Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic cells. However, the extent of variation in TE transcript levels across different tissues and different individuals are unknown, and the co-expression between TEs and host gene mRNAs have not been examined. Results: Here we report the variation in TE derived transcript levels across tissues and between individuals observed in the non-tumorous tissues collected for The Cancer Genome Atlas. We found core TE co-expression modules consisting mainly of transposons, showing correlated expression across broad classes of TEs. Despite this co-expression within tissues, there are individual TE loci that exhibit tissue-specific expression patterns, when compared across tissues. The core TE modules were negatively correlated with other gene modules that consisted of immune response genes in interferon signaling. KRAB Zinc Finger Proteins (KZFPs) were over-represented gene members of the TE modules, showing positive correlation across multiple tissues. But we did not find overlap between TE-KZFP pairs that are co-expressed and TE-KZFP pairs that are bound in published ChIP-seq studies. Conclusions: We find unexpected variation in TE derived transcripts, within and across non-tumorous tissues. We describe a broad view of the RNA state for non-tumorous tissues exhibiting higher level of TE transcripts. Tissues with higher level of TE transcripts have a broad range of TEs co-expressed, with high expression of a large number of KZFPs, and lower RNA levels of immune genes

Constructive Multiuser Interference in Symbol Level Precoding for the MISO Downlink Channel

This paper investigates the problem of interference among the simultaneous multiuser transmissions in the downlink of multiple antennas systems. Using symbol level precoding, a new approach towards the multiuser interference is discussed along this paper. The concept of exploiting the interference between the spatial multiuser transmissions by jointly utilizing the data information (DI) and channel state information (CSI), in order to design symbol-level precoders, is proposed. In this direction, the interference among the data streams is transformed under certain conditions to useful signal that can improve the signal to interference noise ratio (SINR) of the downlink transmissions. We propose a maximum ratio transmission (MRT) based algorithm that jointly exploits DI and CSI to glean the benefits from constructive multiuser interference. Subsequently, a relation between the constructive interference downlink transmission and physical layer multicasting is established. In this context, novel constructive interference precoding techniques that tackle the transmit power minimization (min power) with individual SINR constraints at each user's receivers is proposed. Furthermore, fairness through maximizing the weighted minimum SINR (max min SINR) of the users is addressed by finding the link between the min power and max min SINR problems. Moreover, heuristic precoding techniques are proposed to tackle the weighted sum rate problem. Finally, extensive numerical results show that the proposed schemes outperform other state of the art techniques.Comment: Submitted to IEEE Transactions on Signal Processin

Degrees of Freedom of Time Correlated MISO Broadcast Channel with Delayed CSIT

We consider the time correlated multiple-input single-output (MISO) broadcast channel where the transmitter has imperfect knowledge on the current channel state, in addition to delayed channel state information. By representing the quality of the current channel state information as P^-{\alpha} for the signal-to-noise ratio P and some constant {\alpha} \geq 0, we characterize the optimal degree of freedom region for this more general two-user MISO broadcast correlated channel. The essential ingredients of the proposed scheme lie in the quantization and multicasting of the overheard interferences, while broadcasting new private messages. Our proposed scheme smoothly bridges between the scheme recently proposed by Maddah-Ali and Tse with no current state information and a simple zero-forcing beamforming with perfect current state information.Comment: revised and final version, to appear in IEEE transactions on Information Theor