Monte Carlo-based Noise Compensation in Coil Intensity Corrected Endorectal MRI

Background: Prostate cancer is one of the most common forms of cancer found in males making early diagnosis important. Magnetic resonance imaging (MRI) has been useful in visualizing and localizing tumor candidates and with the use of endorectal coils (ERC), the signal-to-noise ratio (SNR) can be improved. The coils introduce intensity inhomogeneities and the surface coil intensity correction built into MRI scanners is used to reduce these inhomogeneities. However, the correction typically performed at the MRI scanner level leads to noise amplification and noise level variations. Methods: In this study, we introduce a new Monte Carlo-based noise compensation approach for coil intensity corrected endorectal MRI which allows for effective noise compensation and preservation of details within the prostate. The approach accounts for the ERC SNR profile via a spatially-adaptive noise model for correcting non-stationary noise variations. Such a method is useful particularly for improving the image quality of coil intensity corrected endorectal MRI data performed at the MRI scanner level and when the original raw data is not available. Results: SNR and contrast-to-noise ratio (CNR) analysis in patient experiments demonstrate an average improvement of 11.7 dB and 11.2 dB respectively over uncorrected endorectal MRI, and provides strong performance when compared to existing approaches. Conclusions: A new noise compensation method was developed for the purpose of improving the quality of coil intensity corrected endorectal MRI data performed at the MRI scanner level. We illustrate that promising noise compensation performance can be achieved for the proposed approach, which is particularly important for processing coil intensity corrected endorectal MRI data performed at the MRI scanner level and when the original raw data is not available.Comment: 23 page

Autofocus for digital Fresnel holograms by use of a Fresnelet-sparsity criterion

We propose a robust autofocus method for reconstructing digital Fresnel holograms. The numerical reconstruction involves simulating the propagation of a complex wave front to the appropriate distance. Since the latter value is difficult to determine manually, it is desirable to rely on an automatic procedure for finding the optimal distance to achieve high-quality reconstructions. Our algorithm maximizes a sharpness metric related to the sparsity of the signal’s expansion in distance-dependent waveletlike Fresnelet bases. We show results from simulations and experimental situations that confirm its applicability

Robust Automatic Focus Algorithm for Low Contrast Images Using a New Contrast Measure

Low contrast images, suffering from a lack of sharpness, are easily influenced by noise. As a result, many local false peaks may be generated in contrast measurements, making it difficult for the camera’s passive auto-focus system to perform its function of locating the focused peak. In this paper, a new passive auto-focus algorithm is proposed to address this problem. First, a noise reduction preprocessing is introduced to make our algorithm robust to both additive noise and multiplicative noise. Then, a new contrast measure is presented to bring in local false peaks, ensuring the presence of a well defined focused peak. In order to gauge the performance of our algorithm, a modified peak search algorithm is used in the experiments. The experimental results from an actual digital camera validate the effectiveness of our proposed algorithm

Gradient-adaptive Nonlinear Sharpening for Dental Radiographs

Unsharp Masking is a popular image processing technique used for improving the sharpness of structures on dental radiographs. However, it produces overshoot artefact and intolerably amplifies noise. On radiographs, the overshoot artefact often resembles the indications of prosthesis misfit, pathosis, and pathological features associated with restorations. A noise- robust alternative to the Unsharp Masking algorithm, termed Gradient-adaptive Nonlinear Sharpening (GNS) which is free from overshoot and discontinuity artefacts, is proposed in this paper. In GNS, the product of the arbitrary scalar termed as ‘scale’ and the difference between the output of the Adaptive Edge Smoothing Filter (AESF) and the input image, weighted by the normalized gradient magnitude is added to the input image. AESF is a locally-adaptive 2D Gaussian smoothing kernel whose variance is directly proportional to the local value of the gradient magnitude. The dataset employed in this paper is downloaded from the Mendeley data repository having annotated panoramic dental radiographs of 116 patients. On 116 dental radiographs, the values of Saturation Evaluation Index (SEI), Sharpness of Ridges (SOR), Edge Model Based Contrast Metric (EMBCM), and Visual Information Fidelity (VIF) exhibited by the Unsharp Masking are 0.0048 ± 0.0021, 4.4 × 1013 ± 3.8 × 1013, 0.2634 ± 0.2732 and 0.9898 ± 0.0122. The values of these quality metrics corresponding to the GNS are 0.0042 ± 0.0017, 2.2 × 1013 ± 1.8 × 1013, 0.5224 ± 0.1825, and 1.0094 ± 0.0094. GNS exhibited lower values of SEI and SOR and higher values of EMBCM and VIF, compared to the Unsharp Masking. Lower values of SEI and SOR, respectively indicate that GNS is free from overshoot artefact and saturation and the quality of edges in the output images of GNS is less affected by noise. Higher values of EMBCM and VIF, respectively confirm that GNS is free from haloes as it produces thin and sharp edges and the sharpened images are of good information fidelity