Consciousness CLEARS the Mind

A full understanding of consciouness requires that we identify the brain processes from which conscious experiences emerge. What are these processes, and what is their utility in supporting successful adaptive behaviors? Adaptive Resonance Theory (ART) predicted a functional link between processes of Consciousness, Learning, Expectation, Attention, Resonance, and Synchrony (CLEARS), includes the prediction that "all conscious states are resonant states." This connection clarifies how brain dynamics enable a behaving individual to autonomously adapt in real time to a rapidly changing world. The present article reviews theoretical considerations that predicted these functional links, how they work, and some of the rapidly growing body of behavioral and brain data that have provided support for these predictions. The article also summarizes ART models that predict functional roles for identified cells in laminar thalamocortical circuits, including the six layered neocortical circuits and their interactions with specific primary and higher-order specific thalamic nuclei and nonspecific nuclei. These prediction include explanations of how slow perceptual learning can occur more frequently in superficial cortical layers. ART traces these properties to the existence of intracortical feedback loops, and to reset mechanisms whereby thalamocortical mismatches use circuits such as the one from specific thalamic nuclei to nonspecific thalamic nuclei and then to layer 4 of neocortical areas via layers 1-to-5-to-6-to-4.National Science Foundation (SBE-0354378); Office of Naval Research (N00014-01-1-0624

From data towards knowledge: Revealing the architecture of signaling systems by unifying knowledge mining and data mining of systematic perturbation data

Genetic and pharmacological perturbation experiments, such as deleting a gene and monitoring gene expression responses, are powerful tools for studying cellular signal transduction pathways. However, it remains a challenge to automatically derive knowledge of a cellular signaling system at a conceptual level from systematic perturbation-response data. In this study, we explored a framework that unifies knowledge mining and data mining approaches towards the goal. The framework consists of the following automated processes: 1) applying an ontology-driven knowledge mining approach to identify functional modules among the genes responding to a perturbation in order to reveal potential signals affected by the perturbation; 2) applying a graph-based data mining approach to search for perturbations that affect a common signal with respect to a functional module, and 3) revealing the architecture of a signaling system organize signaling units into a hierarchy based on their relationships. Applying this framework to a compendium of yeast perturbation-response data, we have successfully recovered many well-known signal transduction pathways; in addition, our analysis have led to many hypotheses regarding the yeast signal transduction system; finally, our analysis automatically organized perturbed genes as a graph reflecting the architect of the yeast signaling system. Importantly, this framework transformed molecular findings from a gene level to a conceptual level, which readily can be translated into computable knowledge in the form of rules regarding the yeast signaling system, such as "if genes involved in MAPK signaling are perturbed, genes involved in pheromone responses will be differentially expressed"

The Ouroboros Model

At the core of the Ouroboros Model lies a self-referential recursive process with alternating phases of data acquisition and evaluation. Memory entries are organized in schemata. Activation at a time of part of a schema biases the whole structure and, in particular, missing features, thus triggering expectations. An iterative recursive monitor process termed ‘consumption analysis’ is then checking how well such expectations fit with successive activations. A measure for the goodness of fit, “emotion”, provides feedback as (self-) monitoring signal. Contradictions between anticipations based on previous experience and actual current data are highlighted as well as minor gaps and deficits. The basic algorithm can be applied to goal directed movements as well as to abstract rational reasoning when weighing evidence for and against some remote theories. A sketch is provided how the Ouroboros Model can shed light on rather different characteristics of human behavior including learning and meta-learning. Partial implementations proved effective in dedicated safety systems

Backwards is the way forward: feedback in the cortical hierarchy predicts the expected future

Clark offers a powerful description of the brain as a prediction machine, which offers progress on two distinct levels. First, on an abstract conceptual level, it provides a unifying framework for perception, action, and cognition (including subdivisions such as attention, expectation, and imagination). Second, hierarchical prediction offers progress on a concrete descriptive level for testing and constraining conceptual elements and mechanisms of predictive coding models (estimation of predictions, prediction errors, and internal models)

A Convolutional Neural Network model based on Neutrosophy for Noisy Speech Recognition

Convolutional neural networks are sensitive to unknown noisy condition in the test phase and so their performance degrades for the noisy data classification task including noisy speech recognition. In this research, a new convolutional neural network (CNN) model with data uncertainty handling; referred as NCNN (Neutrosophic Convolutional Neural Network); is proposed for classification task. Here, speech signals are used as input data and their noise is modeled as uncertainty. In this task, using speech spectrogram, a definition of uncertainty is proposed in neutrosophic (NS) domain. Uncertainty is computed for each Time-frequency point of speech spectrogram as like a pixel. Therefore, uncertainty matrix with the same size of spectrogram is created in NS domain. In the next step, a two parallel paths CNN classification model is proposed. Speech spectrogram is used as input of the first path and uncertainty matrix for the second path. The outputs of two paths are combined to compute the final output of the classifier. To show the effectiveness of the proposed method, it has been compared with conventional CNN on the isolated words of Aurora2 dataset. The proposed method achieves the average accuracy of 85.96 in noisy train data. It is more robust against Car, Airport and Subway noises with accuracies 90, 88 and 81 in test sets A, B and C, respectively. Results show that the proposed method outperforms conventional CNN with the improvement of 6, 5 and 2 percentage in test set A, test set B and test sets C, respectively. It means that the proposed method is more robust against noisy data and handle these data effectively.Comment: International conference on Pattern Recognition and Image Analysis (IPRIA 2019