20,976 research outputs found
PCA-RECT: An Energy-efficient Object Detection Approach for Event Cameras
We present the first purely event-based, energy-efficient approach for object
detection and categorization using an event camera. Compared to traditional
frame-based cameras, choosing event cameras results in high temporal resolution
(order of microseconds), low power consumption (few hundred mW) and wide
dynamic range (120 dB) as attractive properties. However, event-based object
recognition systems are far behind their frame-based counterparts in terms of
accuracy. To this end, this paper presents an event-based feature extraction
method devised by accumulating local activity across the image frame and then
applying principal component analysis (PCA) to the normalized neighborhood
region. Subsequently, we propose a backtracking-free k-d tree mechanism for
efficient feature matching by taking advantage of the low-dimensionality of the
feature representation. Additionally, the proposed k-d tree mechanism allows
for feature selection to obtain a lower-dimensional dictionary representation
when hardware resources are limited to implement dimensionality reduction.
Consequently, the proposed system can be realized on a field-programmable gate
array (FPGA) device leading to high performance over resource ratio. The
proposed system is tested on real-world event-based datasets for object
categorization, showing superior classification performance and relevance to
state-of-the-art algorithms. Additionally, we verified the object detection
method and real-time FPGA performance in lab settings under non-controlled
illumination conditions with limited training data and ground truth
annotations.Comment: Accepted in ACCV 2018 Workshops, to appea
Computational intelligence approaches to robotics, automation, and control [Volume guest editors]
No abstract available
Spherical harmonics coeffcients for ligand-based virtual screening of cyclooxygenase inhibitors
Background: Molecular descriptors are essential for many applications in computational chemistry, such as ligand-based similarity searching. Spherical harmonics have previously been suggested as comprehensive descriptors of molecular structure and properties. We investigate a spherical harmonics descriptor for shape-based virtual screening. Methodology/Principal Findings: We introduce and validate a partially rotation-invariant three-dimensional molecular shape descriptor based on the norm of spherical harmonics expansion coefficients. Using this molecular representation, we parameterize molecular surfaces, i.e., isosurfaces of spatial molecular property distributions. We validate the shape descriptor in a comprehensive retrospective virtual screening experiment. In a prospective study, we virtually screen a large compound library for cyclooxygenase inhibitors, using a self-organizing map as a pre-filter and the shape descriptor for candidate prioritization. Conclusions/Significance: 12 compounds were tested in vitro for direct enzyme inhibition and in a whole blood assay. Active compounds containing a triazole scaffold were identified as direct cyclooxygenase-1 inhibitors. This outcome corroborates the usefulness of spherical harmonics for representation of molecular shape in virtual screening of large compound collections. The combination of pharmacophore and shape-based filtering of screening candidates proved to be a straightforward approach to finding novel bioactive chemotypes with minimal experimental effort
On the Collaboration of an Automatic Path-Planner and a Human User for Path-Finding in Virtual Industrial Scenes
This paper describes a global interactive framework enabling an automatic path-planner and a user to collaborate for finding a path in cluttered virtual environments. First, a collaborative architecture including the user and the planner is described. Then, for real time purpose, a motion planner divided into different steps is presented. First, a preliminary workspace discretization is done without time limitations at the beginning of the simulation. Then, using these pre-computed data, a second algorithm finds a collision free path in real time. Once the path is found, an haptic artificial guidance on the path is provided to the user. The user can then influence the planner by not following the path and automatically order a new path research. The performances are measured on tests based on assembly simulation in CAD scenes
- …