Deformed Jarzynski Equality

The well-known Jarzynski equality, often written in the form $e^{-\beta\Delta F}=\langle e^{-\beta W}\rangle$, provides a non-equilibrium means to measure the free energy difference $\Delta F$ of a system at the same inverse temperature $\beta$ based on an ensemble average of non-equilibrium work $W$. The accuracy of Jarzynski's measurement scheme was known to be determined by the variance of exponential work, denoted as ${\rm var}\left(e^{-\beta W}\right)$. However, it was recently found that ${\rm var}\left(e^{-\beta W}\right)$ can systematically diverge in both classical and quantum cases. Such divergence will necessarily pose a challenge in the applications of Jarzynski equality because it may dramatically reduce the efficiency in determining $\Delta F$. In this work, we present a deformed Jarzynski equality for both classical and quantum non-equilibrium statistics, in efforts to reuse experimental data that already suffers from a diverging ${\rm var}\left(e^{-\beta W}\right)$. The main feature of our deformed Jarzynski equality is that it connects free energies at different temperatures and it may still work efficiently subject to a diverging ${\rm var}\left(e^{-\beta W}\right)$. The conditions for applying our deformed Jarzynski equality may be met in experimental and computational situations. If so, then there is no need to redesign experimental or simulation methods. Furthermore, using the deformed Jarzynski equality, we exemplify the distinct behaviors of classical and quantum work fluctuations for the case of a time-dependent driven harmonic oscillator dynamics and provide insights into the essential performance differences between classical and quantum Jarzynski equalities.Comment: 24 pages, 1 figure, accepted version to appear in Entropy (Special Issue on "Quantum Thermodynamics"

Developments in Random Matrix Theory

In this preface to the Journal of Physics A, Special Edition on Random Matrix Theory, we give a review of the main historical developments of random matrix theory. A short summary of the papers that appear in this special edition is also given.Comment: 22 pages, Late

On Random Matrix Averages Involving Half-Integer Powers of GOE Characteristic Polynomials

Correlation functions involving products and ratios of half-integer powers of characteristic polynomials of random matrices from the Gaussian Orthogonal Ensemble (GOE) frequently arise in applications of Random Matrix Theory (RMT) to physics of quantum chaotic systems, and beyond. We provide an explicit evaluation of the large-$N$ limits of a few non-trivial objects of that sort within a variant of the supersymmetry formalism, and via a related but different method. As one of the applications we derive the distribution of an off-diagonal entry $K_{ab}$ of the resolvent (or Wigner $K$-matrix) of GOE matrices which, among other things, is of relevance for experiments on chaotic wave scattering in electromagnetic resonators.Comment: 25 pages (2 figures); published version (conclusion added, minor changes

Stable Feature Selection for Biomarker Discovery

Feature selection techniques have been used as the workhorse in biomarker discovery applications for a long time. Surprisingly, the stability of feature selection with respect to sampling variations has long been under-considered. It is only until recently that this issue has received more and more attention. In this article, we review existing stable feature selection methods for biomarker discovery using a generic hierarchal framework. We have two objectives: (1) providing an overview on this new yet fast growing topic for a convenient reference; (2) categorizing existing methods under an expandable framework for future research and development

Generalized Quantum Dynamics as Pre-Quantum Mechanics

We address the issue of when generalized quantum dynamics, which is a classical symplectic dynamics for noncommuting operator phase space variables based on a graded total trace Hamiltonian ${\bf H}$, reduces to Heisenberg picture complex quantum mechanics. We begin by showing that when ${\bf H}={\bf Tr} H$, with $H$ a Weyl ordered operator Hamiltonian, then the generalized quantum dynamics operator equations of motion agree with those obtained from $H$ in the Heisenberg picture by using canonical commutation relations. The remainder of the paper is devoted to a study of how an effective canonical algebra can arise, without this condition simply being imposed by fiat on the operator initial values. We first show that for any total trace Hamiltonian which involves no noncommutative constants, there is a conserved anti--self--adjoint operator $\tilde C$ with a structure which is closely related to the canonical commutator algebra. We study the canonical transformations of generalized quantum dynamics, and show that $\tilde C$ is a canonical invariant, as is the operator phase space volume element. The latter result is a generalization of Liouville's theorem, and permits the application of statistical mechanical methods to determine the canonical ensemble governing the equilibrium distribution of operator initial values. We give arguments based on a Ward identity analogous to the equipartition theorem of classical statistical mechanics, suggesting that statistical ensemble averages of Weyl ordered polynomials in the operator phase space variables correspond to the Wightman functions of a unitary complex quantum mechanics, with a conserved operator Hamiltonian and with the standard canonical commutation relations obeyed by Weyl ordered operator strings. Thus there is a well--defined sense inComment: 79 pages, no figures, plain te