Outlier Detection from Network Data with Subnetwork Interpretation

Detecting a small number of outliers from a set of data observations is always challenging. This problem is more difficult in the setting of multiple network samples, where computing the anomalous degree of a network sample is generally not sufficient. In fact, explaining why the network is exceptional, expressed in the form of subnetwork, is also equally important. In this paper, we develop a novel algorithm to address these two key problems. We treat each network sample as a potential outlier and identify subnetworks that mostly discriminate it from nearby regular samples. The algorithm is developed in the framework of network regression combined with the constraints on both network topology and L1-norm shrinkage to perform subnetwork discovery. Our method thus goes beyond subspace/subgraph discovery and we show that it converges to a global optimum. Evaluation on various real-world network datasets demonstrates that our algorithm not only outperforms baselines in both network and high dimensional setting, but also discovers highly relevant and interpretable local subnetworks, further enhancing our understanding of anomalous networks

Mining Mid-level Features for Action Recognition Based on Effective Skeleton Representation

Recently, mid-level features have shown promising performance in computer vision. Mid-level features learned by incorporating class-level information are potentially more discriminative than traditional low-level local features. In this paper, an effective method is proposed to extract mid-level features from Kinect skeletons for 3D human action recognition. Firstly, the orientations of limbs connected by two skeleton joints are computed and each orientation is encoded into one of the 27 states indicating the spatial relationship of the joints. Secondly, limbs are combined into parts and the limb's states are mapped into part states. Finally, frequent pattern mining is employed to mine the most frequent and relevant (discriminative, representative and non-redundant) states of parts in continuous several frames. These parts are referred to as Frequent Local Parts or FLPs. The FLPs allow us to build powerful bag-of-FLP-based action representation. This new representation yields state-of-the-art results on MSR DailyActivity3D and MSR ActionPairs3D

ProtNN: Fast and Accurate Nearest Neighbor Protein Function Prediction based on Graph Embedding in Structural and Topological Space

Studying the function of proteins is important for understanding the molecular mechanisms of life. The number of publicly available protein structures has increasingly become extremely large. Still, the determination of the function of a protein structure remains a difficult, costly, and time consuming task. The difficulties are often due to the essential role of spatial and topological structures in the determination of protein functions in living cells. In this paper, we propose ProtNN, a novel approach for protein function prediction. Given an unannotated protein structure and a set of annotated proteins, ProtNN finds the nearest neighbor annotated structures based on protein-graph pairwise similarities. Given a query protein, ProtNN finds the nearest neighbor reference proteins based on a graph representation model and a pairwise similarity between vector embedding of both query and reference protein-graphs in structural and topological spaces. ProtNN assigns to the query protein the function with the highest number of votes across the set of k nearest neighbor reference proteins, where k is a user-defined parameter. Experimental evaluation demonstrates that ProtNN is able to accurately classify several datasets in an extremely fast runtime compared to state-of-the-art approaches. We further show that ProtNN is able to scale up to a whole PDB dataset in a single-process mode with no parallelization, with a gain of thousands order of magnitude of runtime compared to state-of-the-art approaches

Multi-graph-view subgraph mining for graph classification

© 2015, Springer-Verlag London. In this paper, we formulate a new multi-graph-view learning task, where each object to be classified contains graphs from multiple graph-views. This problem setting is essentially different from traditional single-graph-view graph classification, where graphs are collected from one single-feature view. To solve the problem, we propose a cross graph-view subgraph feature-based learning algorithm that explores an optimal set of subgraphs, across multiple graph-views, as features to represent graphs. Specifically, we derive an evaluation criterion to estimate the discriminative power and redundancy of subgraph features across all views, with a branch-and-bound algorithm being proposed to prune subgraph search space. Because graph-views may complement each other and play different roles in a learning task, we assign each view with a weight value indicating its importance to the learning task and further use an optimization process to find optimal weight values for each graph-view. The iteration between cross graph-view subgraph scoring and graph-view weight updating forms a closed loop to find optimal subgraphs to represent graphs for multi-graph-view learning. Experiments and comparisons on real-world tasks demonstrate the algorithm’s superior performance

Spiking neurons with short-term synaptic plasticity form superior generative networks

Spiking networks that perform probabilistic inference have been proposed both as models of cortical computation and as candidates for solving problems in machine learning. However, the evidence for spike-based computation being in any way superior to non-spiking alternatives remains scarce. We propose that short-term plasticity can provide spiking networks with distinct computational advantages compared to their classical counterparts. In this work, we use networks of leaky integrate-and-fire neurons that are trained to perform both discriminative and generative tasks in their forward and backward information processing paths, respectively. During training, the energy landscape associated with their dynamics becomes highly diverse, with deep attractor basins separated by high barriers. Classical algorithms solve this problem by employing various tempering techniques, which are both computationally demanding and require global state updates. We demonstrate how similar results can be achieved in spiking networks endowed with local short-term synaptic plasticity. Additionally, we discuss how these networks can even outperform tempering-based approaches when the training data is imbalanced. We thereby show how biologically inspired, local, spike-triggered synaptic dynamics based simply on a limited pool of synaptic resources can allow spiking networks to outperform their non-spiking relatives.Comment: corrected typo in abstrac