Burn wound classification model using spatial frequency-domain imaging and machine learning.

Accurate assessment of burn severity is critical for wound care and the course of treatment. Delays in classification translate to delays in burn management, increasing the risk of scarring and infection. To this end, numerous imaging techniques have been used to examine tissue properties to infer burn severity. Spatial frequency-domain imaging (SFDI) has also been used to characterize burns based on the relationships between histologic observations and changes in tissue properties. Recently, machine learning has been used to classify burns by combining optical features from multispectral or hyperspectral imaging. Rather than employ models of light propagation to deduce tissue optical properties, we investigated the feasibility of using SFDI reflectance data at multiple spatial frequencies, with a support vector machine (SVM) classifier, to predict severity in a porcine model of graded burns. Calibrated reflectance images were collected using SFDI at eight wavelengths (471 to 851 nm) and five spatial frequencies (0 to 0.2  mm  -  1). Three models were built from subsets of this initial dataset. The first subset included data taken at all wavelengths with the planar (0  mm  -  1) spatial frequency, the second comprised data at all wavelengths and spatial frequencies, and the third used all collected data at values relative to unburned tissue. These data subsets were used to train and test cubic SVM models, and compared against burn status 28 days after injury. Model accuracy was established through leave-one-out cross-validation testing. The model based on images obtained at all wavelengths and spatial frequencies predicted burn severity at 24 h with 92.5% accuracy. The model composed of all values relative to unburned skin was 94.4% accurate. By comparison, the model that employed only planar illumination was 88.8% accurate. This investigation suggests that the combination of SFDI with machine learning has potential for accurately predicting burn severity

Generic Black-Box End-to-End Attack Against State of the Art API Call Based Malware Classifiers

In this paper, we present a black-box attack against API call based machine learning malware classifiers, focusing on generating adversarial sequences combining API calls and static features (e.g., printable strings) that will be misclassified by the classifier without affecting the malware functionality. We show that this attack is effective against many classifiers due to the transferability principle between RNN variants, feed forward DNNs, and traditional machine learning classifiers such as SVM. We also implement GADGET, a software framework to convert any malware binary to a binary undetected by malware classifiers, using the proposed attack, without access to the malware source code.Comment: Accepted as a conference paper at RAID 201

KISS: Stochastic Packet Inspection Classifier for UDP Traffic

This paper proposes KISS, a novel Internet classifica- tion engine. Motivated by the expected raise of UDP traffic, which stems from the momentum of Peer-to-Peer (P2P) streaming appli- cations, we propose a novel classification framework that leverages on statistical characterization of payload. Statistical signatures are derived by the means of a Chi-Square-like test, which extracts the protocol "format," but ignores the protocol "semantic" and "synchronization" rules. The signatures feed a decision process based either on the geometric distance among samples, or on Sup- port Vector Machines. KISS is very accurate, and its signatures are intrinsically robust to packet sampling, reordering, and flow asym- metry, so that it can be used on almost any network. KISS is tested in different scenarios, considering traditional client-server proto- cols, VoIP, and both traditional and new P2P Internet applications. Results are astonishing. The average True Positive percentage is 99.6%, with the worst case equal to 98.1,% while results are al- most perfect when dealing with new P2P streaming applications

Elephant Search with Deep Learning for Microarray Data Analysis

Even though there is a plethora of research in Microarray gene expression data analysis, still, it poses challenges for researchers to effectively and efficiently analyze the large yet complex expression of genes. The feature (gene) selection method is of paramount importance for understanding the differences in biological and non-biological variation between samples. In order to address this problem, a novel elephant search (ES) based optimization is proposed to select best gene expressions from the large volume of microarray data. Further, a promising machine learning method is envisioned to leverage such high dimensional and complex microarray dataset for extracting hidden patterns inside to make a meaningful prediction and most accurate classification. In particular, stochastic gradient descent based Deep learning (DL) with softmax activation function is then used on the reduced features (genes) for better classification of different samples according to their gene expression levels. The experiments are carried out on nine most popular Cancer microarray gene selection datasets, obtained from UCI machine learning repository. The empirical results obtained by the proposed elephant search based deep learning (ESDL) approach are compared with most recent published article for its suitability in future Bioinformatics research.Comment: 12 pages, 5 Tabl

Automatic multi-label subject indexing in a multilingual environment

This paper presents an approach to automatically subject index fulltext documents with multiple labels based on binary support vector machines(SVM). The aim was to test the applicability of SVMs with a real world dataset. We have also explored the feasibility of incorporating multilingual background knowledge, as represented in thesauri or ontologies, into our text document representation for indexing purposes. The test set for our evaluations has been compiled from an extensive document base maintained by the Food and Agriculture Organization (FAO) of the United Nations (UN). Empirical results show that SVMs are a good method for automatic multi- label classification of documents in multiple languages