A brief history of the Open Discovery Initiative

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135969/1/leap1078.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/135969/2/leap1078_am.pd

Bringing the Canadian Archive of Women in STEM to Wikidata: How Wikidata can be used in an archival context

Wikidata workshop as part of the 2020 Association of Canadian Archivists (ACA) conferenceLibraries and archives can play a critical role in the creation and curation of data in Wikidata to ensure underrepresented communities are not only included, but also properly described in the knowledge base. This workshop will provide a brief overview of Wikidata in the archival context and its possible uses. We will also share our experiences using Wikidata for the the Canadian Archive of Women in STEM initiative (https://biblio.uottawa.ca/en/women-in-stem/about) based on the WikiProject Archival Description initiative (https://www.wikidata.org/wiki/Wikidata:WikiProject_Archival_Description). The goal of the Canadian Archive of Women in STEM is to bring attention to and promote the discovery of the archival records of women in STEM held by Canadian institutions–a bilingual portal containing descriptive metadata, a biographical sketch/admin history about the women/organizations and information about the host institution–in order to provide a simplified avenue for researchers to discover all available holdings. Contributing the archival metadata and the biographical sketch, as well as links to the host institutions to Wikidata could further increase the visibility of collections, finding aids, as well as the institutions themselves, beyond archival or library systems. This workshop is designed to be interactive with a series of hands-on activities which includes a demonstration of how to contribute content from archival finding aids to Wikidata as well as an introduction on efficient workflows and useful tools for contributing, visualizing and querying the data. This workshop aims to encourage archivists to participate in the open knowledge movement and contribute their unique collections to Wikidata to expand their findability and reach

DeWitt Wallace Library Annual Report 2014-2015

Summary of library and media services activities for 2014-201

Integrative biological simulation praxis: Considerations from physics, philosophy, and data/model curation practices

Integrative biological simulations have a varied and controversial history in the biological sciences. From computational models of organelles, cells, and simple organisms, to physiological models of tissues, organ systems, and ecosystems, a diverse array of biological systems have been the target of large-scale computational modeling efforts. Nonetheless, these research agendas have yet to prove decisively their value among the broader community of theoretical and experimental biologists. In this commentary, we examine a range of philosophical and practical issues relevant to understanding the potential of integrative simulations. We discuss the role of theory and modeling in different areas of physics and suggest that certain sub-disciplines of physics provide useful cultural analogies for imagining the future role of simulations in biological research. We examine philosophical issues related to modeling which consistently arise in discussions about integrative simulations and suggest a pragmatic viewpoint that balances a belief in philosophy with the recognition of the relative infancy of our state of philosophical understanding. Finally, we discuss community workflow and publication practices to allow research to be readily discoverable and amenable to incorporation into simulations. We argue that there are aligned incentives in widespread adoption of practices which will both advance the needs of integrative simulation efforts as well as other contemporary trends in the biological sciences, ranging from open science and data sharing to improving reproducibility.Comment: 10 page

Report of the Stanford Linked Data Workshop

The Stanford University Libraries and Academic Information Resources (SULAIR) with the Council on Library and Information Resources (CLIR) conducted at week-long workshop on the prospects for a large scale, multi-national, multi-institutional prototype of a Linked Data environment for discovery of and navigation among the rapidly, chaotically expanding array of academic information resources. As preparation for the workshop, CLIR sponsored a survey by Jerry Persons, Chief Information Architect emeritus of SULAIR that was published originally for workshop participants as background to the workshop and is now publicly available. The original intention of the workshop was to devise a plan for such a prototype. However, such was the diversity of knowledge, experience, and views of the potential of Linked Data approaches that the workshop participants turned to two more fundamental goals: building common understanding and enthusiasm on the one hand and identifying opportunities and challenges to be confronted in the preparation of the intended prototype and its operation on the other. In pursuit of those objectives, the workshop participants produced:1. a value statement addressing the question of why a Linked Data approach is worth prototyping;2. a manifesto for Linked Libraries (and Museums and Archives and …);3. an outline of the phases in a life cycle of Linked Data approaches;4. a prioritized list of known issues in generating, harvesting & using Linked Data;5. a workflow with notes for converting library bibliographic records and other academic metadata to URIs;6. examples of potential “killer apps” using Linked Data: and7. a list of next steps and potential projects.This report includes a summary of the workshop agenda, a chart showing the use of Linked Data in cultural heritage venues, and short biographies and statements from each of the participants

DeWitt Wallace Library Annual Report 2015-2016

Summary of library and media services activities for 2015-201

Evaluating duration of response to treatment in systemic lupus erythematosus clinical trials.

ObjectiveTo evaluate response duration and identify predictors of transitioning into and out of the response state in patients with SLE receiving standard of care (SoC) in 52-week clinical trials.MethodsA multistate model (MSM) allowing for bidirectional transitions between response and non-response states was fit to data on 759 patients with SLE with active disease randomised to SoC. The probability of being in response at 52 weeks, average duration of response (sojourn time) and mean total time in response for SLE Responder Index (SRI-4, SRI-5, SRI-6) and BILAG-based Composite Lupus Assessment (BICLA) were estimated. Predictors of attainment and loss of SRI-5 response were also assessed.ResultsThe MSM estimated probability of being in response at 52 weeks ranged from 42% (SRI-6) to 61% (SRI-4). Mean duration of response ranged from 20.4 weeks (BICLA) to 31.5 weeks (SRI-4). Mean total time in response was 16.4-24.8 weeks. Baseline characteristics predictive of shorter SRI-5 response duration were African descent (p=0.005), longer history of disease (p=0.03), higher anti-dsDNA antibody titres (p=0.039), lower lymphocyte count (p=0.008) and lower haemoglobin (p=0.006). Younger age (p<0.001) and higher protein/creatinine ratio (p<0.001) were associated with higher likelihood of achieving SRI-5 but also shorter response duration.ConclusionFactors associated with disease severity were more predictive of shorter response duration than of 52-week response status. Analysing landmark response rates and response duration using MSM may be a more powerful way to distinguish effective investigational treatments from background SoC, although this remains to be evaluated in future trials