A Speculative Study on 6G

While 5G is being tested worldwide and anticipated to be rolled out gradually in 2019, researchers around the world are beginning to turn their attention to what 6G might be in 10+ years time, and there are already initiatives in various countries focusing on the research of possible 6G technologies. This article aims to extend the vision of 5G to more ambitious scenarios in a more distant future and speculates on the visionary technologies that could provide the step changes needed for enabling 6G

A Speculative Study on 6G

While 5G is being tested worldwide and anticipated to be rolled out gradually in 2019, researchers around the world are beginning to turn their attention to what 6G might be in 10+ years time, and there are already initiatives in various countries focusing on the research of possible 6G technologies. This article aims to extend the vision of 5G to more ambitious scenarios in a more distant future and speculates on the visionary technologies that could provide the step changes needed for enabling 6G.Comment: This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version mayno longer be accessibl

Staining and peeling of the internal limiting membrane using a fluorescent dye (Rhodamine 6 G)

Aim: To assess whether low concentrations of a fluorescent dye such as Rhodamine 6G would help the unaided human eye visualise the vitreous and the internal limiting membrane (ILM) under standard halogen illumination.Material/methods: The UV/Vis absorption (E) and fluorescence (I) spectra of Rhodamine 6G in water were measured and compared with Indocyanine Green (ICG). Surgery was performed in two rhesus monkeys and consisted of standard pars plana vitrectomy with halogen light source used for illumination. Rhodamine 6G was diluted in balanced salt solution (BSS). A few drops of the dye in a concentration of 0.1% (307 mOsm) were applied over the posterior pole in the air-filled globe and washed out by irrigation after 1 min. Immediately after surgery, the globes were enucleated, fixated and prepared for histological evaluation.Results: In contrast to ICG, both the maximum of the absorption and emission of Rhodamin 6G are very much within the spectral sensitivity of the human eye. The Rhodamine 6G--BSS itself appears red in colour. Using a dye concentration of 0.1%, there was no visible red-staining of the ILM as such. As the dye was irrigated out with BSS, a marked green fluorescence of the fluid within the vitreous cavity was noted. With halogen illumination through a standard 20-gauge light pipe, the dye provided a sufficient green fluorescence to identify and safely remove the ILM and to clearly differentiate areas of peeled from non-peeled ILM. During light microscopy, eyes revealed a peeled ILM demarcation with no signs of acute retinal toxicity.Conclusion: The findings indicate that a fluorescent dye can be used for ILM peeling. Assuming that the fluorophore provides a high enough fluorescence quantum yield after adsorption to the ILM, much lower dye concentrations could be used compared with absorbent dyes, thereby minimising toxic effects

Leukocyte margination in alveolar capillaries: Interrelationship with functional capillary geometry and microhemodynamics

The pulmonary capillary microvasculature harbors a large pool of intravascularly marginated leukocytes. In this study, we investigated the interrelationship of leukocyte margination with characteristics of functional capillary geometry and microhemodynamics in alveolar capillary networks. In 22 anesthetized rabbits we assessed functional capillary density, average capillary length, red blood cell velocity and leukocyte kinetics in alveolar capillary networks in vivo by intravital fluorescence microscopy. In alveolar wall areas of 12,800 +/- 1,800 mu m(2), we detected 3.6 +/- 0.5 sticking leukocytes and 21.0 +/- 1.9 functional capillary segments with an average capillary length of 35.7 +/- 2.1 mu m. We calculated that approximately 15% of functional capillary segments are blocked by marginated leukocytes. Leukocyte margination was predominantly observed in capillary networks characterized by a high functional capillary density, short capillary segments and low red blood cell velocities. The multitude of interconnected capillary channels in these networks may allow alveolar blood flow to bypass marginated leukocytes. Hence, this interrelationship may be relevant for maintenance of adequate alveolar perfusion and low capillary network resistance despite excessive leukocyte margination in the pulmonary microvasculature. Local microhemodynamic factors may play a regulatory role in the spatial distribution of leukocyte margination

The Possibility of Inflation in Asymptotically Safe Gravity

We examine the inflationary modes in the cubic curvature theories in the context of asymptotically safe gravity. On the phase space of the Hubble parameter, there exists a critical point which corresponds to the slow-roll inflation in Einstein frame. Most of the e-foldings are attained around the critical point for each inflationary trajectories. If the coupling constants $g_i$ have the parametric relations generated as the power of the relative energy scale of inflation $H_0$ to the ultraviolet cutoff $\Lambda$, a successful inflation with more than 60 e-foldings occurs near the critical point.Comment: 14 pages, 4 figure