18,494 research outputs found
Blockout: Dynamic Model Selection for Hierarchical Deep Networks
Most deep architectures for image classification--even those that are trained
to classify a large number of diverse categories--learn shared image
representations with a single model. Intuitively, however, categories that are
more similar should share more information than those that are very different.
While hierarchical deep networks address this problem by learning separate
features for subsets of related categories, current implementations require
simplified models using fixed architectures specified via heuristic clustering
methods. Instead, we propose Blockout, a method for regularization and model
selection that simultaneously learns both the model architecture and
parameters. A generalization of Dropout, our approach gives a novel
parametrization of hierarchical architectures that allows for structure
learning via back-propagation. To demonstrate its utility, we evaluate Blockout
on the CIFAR and ImageNet datasets, demonstrating improved classification
accuracy, better regularization performance, faster training, and the clear
emergence of hierarchical network structures
Machine Learning and Integrative Analysis of Biomedical Big Data.
Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues
EC3: Combining Clustering and Classification for Ensemble Learning
Classification and clustering algorithms have been proved to be successful
individually in different contexts. Both of them have their own advantages and
limitations. For instance, although classification algorithms are more powerful
than clustering methods in predicting class labels of objects, they do not
perform well when there is a lack of sufficient manually labeled reliable data.
On the other hand, although clustering algorithms do not produce label
information for objects, they provide supplementary constraints (e.g., if two
objects are clustered together, it is more likely that the same label is
assigned to both of them) that one can leverage for label prediction of a set
of unknown objects. Therefore, systematic utilization of both these types of
algorithms together can lead to better prediction performance. In this paper,
We propose a novel algorithm, called EC3 that merges classification and
clustering together in order to support both binary and multi-class
classification. EC3 is based on a principled combination of multiple
classification and multiple clustering methods using an optimization function.
We theoretically show the convexity and optimality of the problem and solve it
by block coordinate descent method. We additionally propose iEC3, a variant of
EC3 that handles imbalanced training data. We perform an extensive experimental
analysis by comparing EC3 and iEC3 with 14 baseline methods (7 well-known
standalone classifiers, 5 ensemble classifiers, and 2 existing methods that
merge classification and clustering) on 13 standard benchmark datasets. We show
that our methods outperform other baselines for every single dataset, achieving
at most 10% higher AUC. Moreover our methods are faster (1.21 times faster than
the best baseline), more resilient to noise and class imbalance than the best
baseline method.Comment: 14 pages, 7 figures, 11 table
A General Spatio-Temporal Clustering-Based Non-local Formulation for Multiscale Modeling of Compartmentalized Reservoirs
Representing the reservoir as a network of discrete compartments with
neighbor and non-neighbor connections is a fast, yet accurate method for
analyzing oil and gas reservoirs. Automatic and rapid detection of coarse-scale
compartments with distinct static and dynamic properties is an integral part of
such high-level reservoir analysis. In this work, we present a hybrid framework
specific to reservoir analysis for an automatic detection of clusters in space
using spatial and temporal field data, coupled with a physics-based multiscale
modeling approach. In this work a novel hybrid approach is presented in which
we couple a physics-based non-local modeling framework with data-driven
clustering techniques to provide a fast and accurate multiscale modeling of
compartmentalized reservoirs. This research also adds to the literature by
presenting a comprehensive work on spatio-temporal clustering for reservoir
studies applications that well considers the clustering complexities, the
intrinsic sparse and noisy nature of the data, and the interpretability of the
outcome.
Keywords: Artificial Intelligence; Machine Learning; Spatio-Temporal
Clustering; Physics-Based Data-Driven Formulation; Multiscale Modelin
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