A nonparametric Bayesian approach to the rare type match problem

The "rare type match problem" is the situation in which the suspect's DNA profile, matching the DNA profile of the crime stain, is not in the database of reference. The evaluation of this match in the light of the two competing hypotheses (the crime stain has been left by the suspect or by another person) is based on the calculation of the likelihood ratio and depends on the population proportions of the DNA profiles, that are unknown. We propose a Bayesian nonparametric method that uses a two-parameter Poisson Dirichlet distribution as a prior over the ranked population proportions, and discards the information about the names of the different DNA profiles. This fits very well the data coming from European Y-STR DNA profiles, and the calculation of the likelihood ratio becomes quite simple thanks to a justified Empirical Bayes approach.Comment: arXiv admin note: text overlap with arXiv:1506.0844

Bayesian nonparametric dependent model for partially replicated data: the influence of fuel spills on species diversity

We introduce a dependent Bayesian nonparametric model for the probabilistic modeling of membership of subgroups in a community based on partially replicated data. The focus here is on species-by-site data, i.e. community data where observations at different sites are classified in distinct species. Our aim is to study the impact of additional covariates, for instance environmental variables, on the data structure, and in particular on the community diversity. To that purpose, we introduce dependence a priori across the covariates, and show that it improves posterior inference. We use a dependent version of the Griffiths-Engen-McCloskey distribution defined via the stick-breaking construction. This distribution is obtained by transforming a Gaussian process whose covariance function controls the desired dependence. The resulting posterior distribution is sampled by Markov chain Monte Carlo. We illustrate the application of our model to a soil microbial dataset acquired across a hydrocarbon contamination gradient at the site of a fuel spill in Antarctica. This method allows for inference on a number of quantities of interest in ecotoxicology, such as diversity or effective concentrations, and is broadly applicable to the general problem of communities response to environmental variables.Comment: Main Paper: 22 pages, 6 figures. Supplementary Material: 11 pages, 1 figur

Philosophy and the practice of Bayesian statistics

A substantial school in the philosophy of science identifies Bayesian inference with inductive inference and even rationality as such, and seems to be strengthened by the rise and practical success of Bayesian statistics. We argue that the most successful forms of Bayesian statistics do not actually support that particular philosophy but rather accord much better with sophisticated forms of hypothetico-deductivism. We examine the actual role played by prior distributions in Bayesian models, and the crucial aspects of model checking and model revision, which fall outside the scope of Bayesian confirmation theory. We draw on the literature on the consistency of Bayesian updating and also on our experience of applied work in social science. Clarity about these matters should benefit not just philosophy of science, but also statistical practice. At best, the inductivist view has encouraged researchers to fit and compare models without checking them; at worst, theorists have actively discouraged practitioners from performing model checking because it does not fit into their framework.Comment: 36 pages, 5 figures. v2: Fixed typo in caption of figure 1. v3: Further typo fixes. v4: Revised in response to referee