14,051 research outputs found
A Deep Learning Reconstruction Framework for Differential Phase-Contrast Computed Tomography with Incomplete Data
Differential phase-contrast computed tomography (DPC-CT) is a powerful
analysis tool for soft-tissue and low-atomic-number samples. Limited by the
implementation conditions, DPC-CT with incomplete projections happens quite
often. Conventional reconstruction algorithms are not easy to deal with
incomplete data. They are usually involved with complicated parameter selection
operations, also sensitive to noise and time-consuming. In this paper, we
reported a new deep learning reconstruction framework for incomplete data
DPC-CT. It is the tight coupling of the deep learning neural network and DPC-CT
reconstruction algorithm in the phase-contrast projection sinogram domain. The
estimated result is the complete phase-contrast projection sinogram not the
artifacts caused by the incomplete data. After training, this framework is
determined and can reconstruct the final DPC-CT images for a given incomplete
phase-contrast projection sinogram. Taking the sparse-view DPC-CT as an
example, this framework has been validated and demonstrated with synthetic and
experimental data sets. Embedded with DPC-CT reconstruction, this framework
naturally encapsulates the physical imaging model of DPC-CT systems and is easy
to be extended to deal with other challengs. This work is helpful to push the
application of the state-of-the-art deep learning theory in the field of
DPC-CT
Quantifying admissible undersampling for sparsity-exploiting iterative image reconstruction in X-ray CT
Iterative image reconstruction (IIR) with sparsity-exploiting methods, such
as total variation (TV) minimization, investigated in compressive sensing (CS)
claim potentially large reductions in sampling requirements. Quantifying this
claim for computed tomography (CT) is non-trivial, because both full sampling
in the discrete-to-discrete imaging model and the reduction in sampling
admitted by sparsity-exploiting methods are ill-defined. The present article
proposes definitions of full sampling by introducing four sufficient-sampling
conditions (SSCs). The SSCs are based on the condition number of the system
matrix of a linear imaging model and address invertibility and stability. In
the example application of breast CT, the SSCs are used as reference points of
full sampling for quantifying the undersampling admitted by reconstruction
through TV-minimization. In numerical simulations, factors affecting admissible
undersampling are studied. Differences between few-view and few-detector bin
reconstruction as well as a relation between object sparsity and admitted
undersampling are quantified.Comment: Revised version that was submitted to IEEE Transactions on Medical
Imaging on 8/16/201
GENFIRE: A generalized Fourier iterative reconstruction algorithm for high-resolution 3D imaging
Tomography has made a radical impact on diverse fields ranging from the study
of 3D atomic arrangements in matter to the study of human health in medicine.
Despite its very diverse applications, the core of tomography remains the same,
that is, a mathematical method must be implemented to reconstruct the 3D
structure of an object from a number of 2D projections. In many scientific
applications, however, the number of projections that can be measured is
limited due to geometric constraints, tolerable radiation dose and/or
acquisition speed. Thus it becomes an important problem to obtain the
best-possible reconstruction from a limited number of projections. Here, we
present the mathematical implementation of a tomographic algorithm, termed
GENeralized Fourier Iterative REconstruction (GENFIRE). By iterating between
real and reciprocal space, GENFIRE searches for a global solution that is
concurrently consistent with the measured data and general physical
constraints. The algorithm requires minimal human intervention and also
incorporates angular refinement to reduce the tilt angle error. We demonstrate
that GENFIRE can produce superior results relative to several other popular
tomographic reconstruction techniques by numerical simulations, and by
experimentally by reconstructing the 3D structure of a porous material and a
frozen-hydrated marine cyanobacterium. Equipped with a graphical user
interface, GENFIRE is freely available from our website and is expected to find
broad applications across different disciplines.Comment: 18 pages, 6 figure
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