Closed-loop control of anesthesia : survey on actual trends, challenges and perspectives

Automation empowers self-sustainable adaptive processes and personalized services in many industries. The implementation of the integrated healthcare paradigm built on Health 4.0 is expected to transform any area in medicine due to the lightning-speed advances in control, robotics, artificial intelligence, sensors etc. The two objectives of this article, as addressed to different entities, are: i) to raise awareness throughout the anesthesiologists about the usefulness of integrating automation and data exchange in their clinical practice for providing increased attention to alarming situations, ii) to provide the actualized insights of drug-delivery research in order to create an opening horizon towards precision medicine with significantly improved human outcomes. This article presents a concise overview on the recent evolution of closed-loop anesthesia delivery control systems by means of control strategies, depth of anesthesia monitors, patient modelling, safety systems, and validation in clinical trials. For decades, anesthesia control has been in the midst of transformative changes, going from simple controllers to integrative strategies of two or more components, but not achieving yet the breakthrough of an integrated system. However, the scientific advances that happen at high speed need a modern review to identify the current technological gaps, societal implications, and implementation barriers. This article provides a good basis for control research in clinical anesthesia to endorse new challenges for intelligent systems towards individualized patient care. At this connection point of clinical and engineering frameworks through (semi-) automation, the following can be granted: patient safety, economical efficiency, and clinicians' efficacy

A Cyber-physical system to improve the management of a large suite of operating rooms

© 2018 ACM Cyber-physical systems have been deployed with considerable success in many industries. However, the implementation of cyber-physical systems in hospitals has been limited. By nature, in clinical operations, patient safety and consideration for health outcomes are of the utmost importance, thus possibly slowing the implementation of innovative solutions with limited history. Revenues from operating room (OR) time and surgery account for about 50% of the income of major hospitals (Erdogan et al. 2011; Cuschieri 2006), but the efficiency of OR utilization is often reported to be relatively low. Therefore, improving OR management with a cyber-physical system should be a priority. In this article, we will report on our experience implementing a cyber-physical system at Houston Methodist Hospital and discuss some of the difficulties and potential drivers for success. Our pilot study was done in the context of the management of a large suite of ORs. It uses the agile codevelopment of a cyber-physical system through an intense collaboration of clinicians and computational scientists. While technology remains the foundation of a cyber-physical system, this experience reinforced that the human factor is an important driving force behind the design that promotes user acceptance