514,307 research outputs found
The nonlinear viscoelastic response of resin matrix composite laminates
Possible treatments of the nonlinear viscoelastic behavior of materials are reviewed. A thermodynamic based approach, developed by Schapery, is discussed and used to interpret the nonlinear viscoelastic response of a graphite epoxy laminate, T300/934. Test data to verify the analysis for Fiberite 934 neat resin as well as transverse and shear properties of the unidirectional T300/934 composited are presented. Long time creep characteristics as a function of stress level and temperature are generated. Favorable comparisons between the traditional, graphical, and the current analytical approaches are shown. A free energy based rupture criterion is proposed as a way to estimate the life that remains in a structure at any time
Volunteer Management Practices and Retention of Volunteers
This report is the second in a series of briefs on a 2003 survey of volunteer management capacity among public charities in the United States. It focuses on charities' adoption of nine volunteer management practices: supervision and communication, liability coverage, screening and matching, regular collection of volunteer numbers and hours written policies and job descriptions, recognition activities, measurement of volunteer impacts, training and professional development, and training for paid staff in working with volunteers. We report on the extent of adoption of these practices by charities with different characteristics, and the relationship between volunteer management practices and retention of volunteers
On the existence of weak solutions to the Cauchy problem for a class of quasilinear hyperbolic equations with a source term.
Following the ideas of D. Serre and J. Shearer in [16], we prove in this paper the existence of a weak solution of the Cauchy problem for the second order quasilinear hyperbolic equation Φtt − σ'(Φx) Φ xx + F(Φ) = 0, (x, t) E R x [0,+1[, where F(Φ) is a suitable source term
Evaluation of energy absorption of new concepts of aircraft composite subfloor intersections
Forty-one composite aircraft subfloor intersection specimens were tested to determine the effects of geometry and material on the energy absorbing behavior, failure characteristics, and post-crush structural integrity of the specimens. The intersections were constructed of twelve ply + or - 45 sub 6 laminates of either Kevlar 49/934 or AS-4/934 graphite-epoxy in heights of 4, 8, and 12 inches. The geometry of the specimens varied in the designs of the intersection attachment angle. Four different geometries were tested
Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma.
BackgroundAlcohol consumption is a well-established risk factor for head and neck squamous cell carcinoma (HNSCC); however, the molecular mechanisms by which alcohol promotes HNSCC pathogenesis and progression remain poorly understood. Our study sought to identify microRNAs that are dysregulated in alcohol-associated HNSCC and investigate their contribution to the malignant phenotype.MethodUsing RNA-sequencing data from 136 HNSCC patients, we compared the expression levels of 1,046 microRNAs between drinking and non-drinking cohorts. Dysregulated microRNAs were verified by qRT-PCR in normal oral keratinocytes treated with biologically relevant doses of ethanol and acetaldehyde. The most promising microRNA candidates were investigated for their effects on cellular proliferation and invasion, sensitivity to cisplatin, and expression of cancer stem cell genes. Finally, putative target genes were identified and evaluated in vitro to further establish roles for these miRNAs in alcohol-associated HNSCC.ResultsFrom RNA-sequencing analysis we identified 8 miRNAs to be significantly upregulated in alcohol-associated HNSCCs. qRT-PCR experiments determined that among these candidates, miR-30a and miR-934 were the most highly upregulated in vitro by alcohol and acetaldehyde. Overexpression of miR-30a and miR-934 in normal and HNSCC cell lines produced up to a 2-fold increase in cellular proliferation, as well as induction of the anti-apoptotic gene BCL-2. Upon inhibition of these miRNAs, HNSCC cell lines exhibited increased sensitivity to cisplatin and reduced matrigel invasion. miRNA knockdown also indicated direct targeting of several tumor suppressor genes by miR-30a and miR-934.ConclusionsAlcohol induces the dysregulation of miR-30a and miR-934, which may play crucial roles in HNSCC pathogenesis and progression. Future investigation of the alcohol-mediated pathways effecting these transformations will prove valuable for furthering the understanding and treatment of alcohol-associated HNSCC
The interlaminar fracture toughness of woven graphite/epoxy composites
The interlaminar fracture toughness of 2-D graphite/epoxy woven composites was determined as a function of stacking sequence, thickness, and weave pattern. Plain, oxford, 5-harness satin, and 8-harness satin weaves of T300/934 material were evaluated by the double cantilever beam test. The fabric material had a G (sub Ic) ranging from 2 to 8 times greater than 0 degrees unidirectional T300/934 tape material. The interlaminar fracture toughness of a particular weave style was dependent on whether the stacking sequence was symmetric or asymmetric and, in some cases, on the fabric orientation
Wilderness attribute mapping in the United Kingdom
A wilderness continuum concept can identify the wilder areas of Britain. Geographical Information Systems are used to present information on these areas and solicit public opinion as to which factors are perceived to be important wilderness quality indicators. Consensus maps are compiled from a composite of individual responses and the results compared to Britain’s network of protected areas
The accelerated characterization of viscoelastic composite materials
Necessary fundamentals relative to composite materials and viscoelasticity are reviewed. The accelerated characterization techniques of time temperature superposition and time temperature stress superposition are described. An experimental procedure for applying the latter to composites is given along with results obtained on a particular T300/934 graphite/epoxy. The accelerated characterization predictions are found in good agreement with actual long term tests. A postcuring phenomenon is discussed that necessitates thermal conditioning of the specimen prior to testing. A closely related phenomenon of physical aging is described as well as the effect of each on the glass transition temperature and strength. Creep rupture results are provided for a variety of geometries and temperatures for T300/934 graphite/epoxy. The results are found to compare reasonably with a modified kinetic rate theory
Space environmental effects on graphite-epoxy compressive properties and epoxy tensile properties
This study characterizes the effects of electron radiation and temperature on a graphite-epoxy composite material. Compressive properties of the T300/934 material system were obtained at -250 F (-157 C), room temperature, and 250 F (121 C). Tensile specimens of the Fiberite 934 epoxy resin were fabricated and tested at room temperature and 250 F (121 C). Testing was conducted in the baseline (nonirradiated) and irradiated conditions. The radiation exposure was designed to simulate 30 year, worst-case exposure in geosynchronous Earth orbit. Mechanical properties tended to degrade at elevated temperature and improve at cryogenic temperature. Irradiation generally degraded properties at all temperatures
On Φ-recurrent N(k)-contact Metric Manifolds
In this paper we prove that a Φ-recurrent N(k)-contact metric manifold is an η-Einstein manifold with constant coefficients. Next, we prove that a 3-dimensional Φ-recurrent N(k)-contact metric manifold
is of constant curvature. The existence of a Φ-recurrent N(k)-contact metric manifold is also proved.</p
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